ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count	geneSymbol	ErichmentScore	-log10(P.adj)	type
hsa04110	Cell cycle	24/197	124/8081	1.49782446617292e-15	3.32517031490388e-13	2.91681606570516e-13	4175/991/994/4171/23594/4085/699/7272/1111/4174/983/9133/4173/4176/701/8318/5111/990/10926/4172/1019/891/1021/5347	24	MCM6/CDC20/CDC25B/MCM2/ORC6/MAD2L1/BUB1/TTK/CHEK1/MCM5/CDK1/CCNB2/MCM4/MCM7/BUB1B/CDC45/PCNA/CDC6/DBF4/MCM3/CDK4/CCNB1/CDK6/PLK1	7.93941378745702	12.478	KEGG
hsa03030	DNA replication	11/197	36/8081	4.82509738609155e-10	5.35585809856162e-08	4.69812113908915e-08	4175/4171/4174/5984/4173/4176/2237/5111/10535/4172/5558	11	MCM6/MCM2/MCM5/RFC4/MCM4/MCM7/FEN1/PCNA/RNASEH2A/MCM3/PRIM2	12.5339819514946	7.271	KEGG
hsa04512	ECM-receptor interaction	13/197	88/8081	1.74509138839098e-07	1.29136762740933e-05	1.1327786205345e-05	3918/3914/3691/375790/3655/6696/3161/1287/1284/3685/3909/3371/3675	13	LAMC2/LAMB3/ITGB4/AGRN/ITGA6/SPP1/HMMR/COL4A5/COL4A2/ITGAV/LAMA3/TNC/ITGA3	6.05981772035072	4.889	KEGG
hsa05222	Small cell lung cancer	12/197	92/8081	2.07202695835879e-06	0.000114997496188913	0.000100874996656941	1163/3918/3914/3655/1164/1287/1019/1284/3685/3909/3675/1021	12	CKS1B/LAMC2/LAMB3/ITGA6/CKS2/COL4A5/CDK4/COL4A2/ITGAV/LAMA3/ITGA3/CDK6	5.35047450893842	3.939	KEGG
hsa04115	p53 signaling pathway	10/197	73/8081	9.63623091952774e-06	0.000427848652827032	0.000375305835813186	637/1111/983/9133/1019/891/3486/5054/6241/1021	10	BID/CHEK1/CDK1/CCNB2/CDK4/CCNB1/IGFBP3/SERPINE1/RRM2/CDK6	5.61921980390793	3.369	KEGG
hsa05165	Human papillomavirus infection	21/197	331/8081	5.25906519438619e-05	0.00194585412192289	0.00170688958063412	3918/3914/3691/8323/3655/528/6696/2535/23462/9636/5610/1287/1019/1284/3685/3909/8772/3371/3675/1021/7477	21	LAMC2/LAMB3/ITGB4/FZD6/ITGA6/ATP6V1C1/SPP1/FZD2/HEY1/ISG15/EIF2AK2/COL4A5/CDK4/COL4A2/ITGAV/LAMA3/FADD/TNC/ITGA3/CDK6/WNT7B	2.60249666446854	2.711	KEGG
hsa05202	Transcriptional misregulation in cancer	14/197	192/8081	0.000238815781937603	0.0075738719414497	0.00664374731706114	5328/51804/3206/4291/6929/3576/4233/4318/6495/8091/3486/2119/860/597	14	PLAU/SIX4/HOXA10/MLF1/TCF3/CXCL8/MET/MMP9/SIX1/HMGA2/IGFBP3/ETV5/RUNX2/BCL2A1	2.99106387478849	2.121	KEGG
hsa04218	Cellular senescence	12/197	156/8081	0.000410740936087589	0.0113980609764306	0.00999829910213211	4605/3710/2305/1111/983/9133/3576/1019/891/3486/5054/1021	12	MYBL2/ITPR3/FOXM1/CHEK1/CDK1/CCNB2/CXCL8/CDK4/CCNB1/IGFBP3/SERPINE1/CDK6	3.15540804373292	1.943	KEGG
hsa04114	Oocyte meiosis	10/197	129/8081	0.0011703195243287	0.0288678816001079	0.0253227031579894	3710/991/6790/4085/699/983/9133/26271/891/5347	10	ITPR3/CDC20/AURKA/MAD2L1/BUB1/CDK1/CCNB2/FBXO5/CCNB1/PLK1	3.17986857120371	1.54	KEGG
hsa05206	MicroRNAs in cancer	17/197	310/8081	0.00145288555126047	0.0322540592379825	0.0282930344192829	5328/994/1789/113130/9493/1786/6624/4233/4318/3925/8091/3371/1942/8626/3236/672/1021	17	PLAU/CDC25B/DNMT3B/CDCA5/KIF23/DNMT1/FSCN1/MET/MMP9/STMN1/HMGA2/TNC/EFNA1/TP63/HOXD10/BRCA1/CDK6	2.24950057311282	1.491	KEGG
hsa04657	IL-17 signaling pathway	8/197	94/8081	0.00200621196841219	0.0390098428171386	0.034219160365911	4322/4312/3576/4318/8772/2919/3627/6364	8	MMP13/MMP1/CXCL8/MMP9/FADD/CXCL1/CXCL10/CCL20	3.49108975051301	1.409	KEGG
hsa03430	Mismatch repair	4/197	23/8081	0.00210864015227776	0.0390098428171386	0.034219160365911	9156/5984/2956/5111	4	EXO1/RFC4/MSH6/PCNA	7.1339660119179	1.409	KEGG
hsa04914	Progesterone-mediated oocyte maturation	8/197	100/8081	0.00296313086073136	0.0476633850943711	0.0418099869248869	994/6790/4085/699/983/9133/891/5347	8	CDC25B/AURKA/MAD2L1/BUB1/CDK1/CCNB2/CCNB1/PLK1	3.28162436548223	1.322	KEGG
hsa03440	Homologous recombination	5/197	41/8081	0.00300579906000538	0.0476633850943711	0.0418099869248869	641/8438/11073/5888/672	5	BLM/RAD54L/TOPBP1/RAD51/BRCA1	5.00247616689365	1.322	KEGG
hsa05146	Amoebiasis	8/197	102/8081	0.00335082082625926	0.049592148228637	0.0435018844110851	3918/3914/3576/1287/1284/3909/2919/7097	8	LAMC2/LAMB3/CXCL8/COL4A5/COL4A2/LAMA3/CXCL1/TLR2	3.21727878968846	1.305	KEGG
R-HSA-69620	Cell Cycle Checkpoints	42/269	293/10554	2.54644404141471e-20	1.73412839220342e-17	1.39652352166007e-17	11065/4175/9212/991/4171/57405/55839/9156/81930/23594/1062/1063/4085/699/2491/641/55388/84515/1111/1058/4174/5984/83540/55143/11004/983/9133/4173/57122/11073/4176/10403/701/8318/332/990/9735/10926/4172/891/672/5347	42	UBE2C/MCM6/AURKB/CDC20/MCM2/SPC25/CENPN/EXO1/KIF18A/ORC6/CENPE/CENPF/MAD2L1/BUB1/CENPI/BLM/MCM10/MCM8/CHEK1/CENPA/MCM5/RFC4/NUF2/CDCA8/KIF2C/CDK1/CCNB2/MCM4/NUP107/TOPBP1/MCM7/NDC80/BUB1B/CDC45/BIRC5/CDC6/KNTC1/DBF4/MCM3/CCNB1/BRCA1/PLK1	5.62401512364084	16.761	Reactome
R-HSA-176974	Unwinding of DNA	11/269	12/10554	2.82686245759495e-17	9.62546666811079e-15	7.75155442319457e-15	4175/4171/84515/4174/51659/9837/4173/4176/8318/4172/84296	11	MCM6/MCM2/MCM8/MCM5/GINS2/GINS1/MCM4/MCM7/CDC45/MCM3/GINS4	35.9646840148699	14.017	Reactome
R-HSA-69190	DNA strand elongation	15/269	32/10554	3.24024038501163e-16	7.35534567397639e-14	5.92338680909143e-14	4175/4171/84515/4174/5984/51659/9837/4173/4176/2237/8318/5111/4172/84296/5558	15	MCM6/MCM2/MCM8/MCM5/RFC4/GINS2/GINS1/MCM4/MCM7/FEN1/CDC45/PCNA/MCM3/GINS4/PRIM2	18.391031598513	13.133	Reactome
R-HSA-453279	Mitotic G1-G1/S phases	27/269	149/10554	5.70640220710144e-16	7.90808051496453e-14	6.36851371558316e-14	4605/1163/51053/4175/4171/23594/55388/84515/4174/7153/983/4173/4176/7083/8318/5111/990/26271/10926/4172/1019/891/6241/7298/5558/81620/1021	27	MYBL2/CKS1B/GMNN/MCM6/MCM2/ORC6/MCM10/MCM8/MCM5/TOP2A/CDK1/MCM4/MCM7/TK1/CDC45/PCNA/CDC6/FBXO5/DBF4/MCM3/CDK4/CCNB1/RRM2/TYMS/PRIM2/CDT1/CDK6	7.10955315486141	13.102	Reactome
R-HSA-68962	Activation of the pre-replicative complex	15/269	33/10554	5.80622651612668e-16	7.90808051496453e-14	6.36851371558316e-14	51053/4175/4171/23594/55388/84515/4174/4173/4176/8318/990/10926/4172/5558/81620	15	GMNN/MCM6/MCM2/ORC6/MCM10/MCM8/MCM5/MCM4/MCM7/CDC45/CDC6/DBF4/MCM3/PRIM2/CDT1	17.8337276106793	13.102	Reactome
R-HSA-2500257	Resolution of Sister Chromatid Cohesion	24/269	124/10554	5.44222751031732e-15	6.17692822421016e-13	4.97438689978127e-13	9212/991/57405/55839/81930/1062/113130/1063/4085/699/2491/1058/83540/55143/11004/983/9133/57122/10403/701/332/9735/891/5347	24	AURKB/CDC20/SPC25/CENPN/KIF18A/CENPE/CDCA5/CENPF/MAD2L1/BUB1/CENPI/CENPA/NUF2/CDCA8/KIF2C/CDK1/CCNB2/NUP107/NDC80/BUB1B/BIRC5/KNTC1/CCNB1/PLK1	7.5937162729344	12.209	Reactome
R-HSA-69206	G1/S Transition	24/269	131/10554	1.98685260699411e-14	1.93292375051856e-12	1.55661685450216e-12	1163/51053/4175/4171/23594/55388/84515/4174/983/4173/4176/7083/8318/5111/990/26271/10926/4172/1019/891/6241/7298/5558/81620	24	CKS1B/GMNN/MCM6/MCM2/ORC6/MCM10/MCM8/MCM5/CDK1/MCM4/MCM7/TK1/CDC45/PCNA/CDC6/FBXO5/DBF4/MCM3/CDK4/CCNB1/RRM2/TYMS/PRIM2/CDT1	7.18794517438066	11.714	Reactome
R-HSA-68877	Mitotic Prometaphase	28/269	198/10554	1.13135699314161e-13	9.5420595719346e-12	7.68438524921235e-12	9212/991/57405/4751/55839/81930/1062/113130/1063/4085/699/2491/1058/83540/23397/55143/64151/11004/983/9133/57122/10403/701/332/9735/891/9918/5347	28	AURKB/CDC20/SPC25/NEK2/CENPN/KIF18A/CENPE/CDCA5/CENPF/MAD2L1/BUB1/CENPI/CENPA/NUF2/NCAPH/CDCA8/NCAPG/KIF2C/CDK1/CCNB2/NUP107/NDC80/BUB1B/BIRC5/KNTC1/CCNB1/NCAPD2/PLK1	5.54827081221133	11.02	Reactome
R-HSA-176187	Activation of ATR in response to replication stress	14/269	37/10554	1.26106514166537e-13	9.5420595719346e-12	7.68438524921235e-12	4175/4171/23594/55388/84515/1111/4174/5984/4173/4176/8318/990/10926/4172	14	MCM6/MCM2/ORC6/MCM10/MCM8/CHEK1/MCM5/RFC4/MCM4/MCM7/CDC45/CDC6/DBF4/MCM3	14.8453732542952	11.02	Reactome
R-HSA-141424	Amplification of signal from the kinetochores	20/269	96/10554	2.52559059981376e-13	1.56357018043016e-11	1.25917005024208e-11	9212/991/57405/55839/81930/1062/1063/4085/699/2491/1058/83540/55143/11004/57122/10403/701/332/9735/5347	20	AURKB/CDC20/SPC25/CENPN/KIF18A/CENPE/CENPF/MAD2L1/BUB1/CENPI/CENPA/NUF2/CDCA8/KIF2C/NUP107/NDC80/BUB1B/BIRC5/KNTC1/PLK1	8.17379182156134	10.806	Reactome
R-HSA-141444	Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal	20/269	96/10554	2.52559059981376e-13	1.56357018043016e-11	1.25917005024208e-11	9212/991/57405/55839/81930/1062/1063/4085/699/2491/1058/83540/55143/11004/57122/10403/701/332/9735/5347	20	AURKB/CDC20/SPC25/CENPN/KIF18A/CENPE/CENPF/MAD2L1/BUB1/CENPI/CENPA/NUF2/CDCA8/KIF2C/NUP107/NDC80/BUB1B/BIRC5/KNTC1/PLK1	8.17379182156134	10.806	Reactome
R-HSA-69618	Mitotic Spindle Checkpoint	21/269	112/10554	5.62124202844785e-13	3.19005485114415e-11	2.56900622528187e-11	11065/9212/991/57405/55839/81930/1062/1063/4085/699/2491/1058/83540/55143/11004/57122/10403/701/332/9735/5347	21	UBE2C/AURKB/CDC20/SPC25/CENPN/KIF18A/CENPE/CENPF/MAD2L1/BUB1/CENPI/CENPA/NUF2/CDCA8/KIF2C/NUP107/NDC80/BUB1B/BIRC5/KNTC1/PLK1	7.3564126394052	10.496	Reactome
R-HSA-1474290	Collagen formation	19/269	90/10554	7.90916155887544e-13	4.07187291816724e-11	3.27914953298575e-11	4322/3918/871/5351/3914/1300/3691/85301/3655/1294/4017/4318/8985/5033/1287/1284/3909/79709/9509	19	MMP13/LAMC2/SERPINH1/PLOD1/LAMB3/COL10A1/ITGB4/COL27A1/ITGA6/COL7A1/LOXL2/MMP9/PLOD3/P4HA1/COL4A5/COL4A2/LAMA3/COLGALT1/ADAMTS2	8.28277571251549	10.39	Reactome
R-HSA-69306	DNA Replication	22/269	127/10554	8.37095754101929e-13	4.07187291816724e-11	3.27914953298575e-11	11065/51053/4175/4171/23594/55388/84515/4174/5984/51659/9837/4173/4176/2237/8318/5111/990/10926/4172/84296/5558/81620	22	UBE2C/GMNN/MCM6/MCM2/ORC6/MCM10/MCM8/MCM5/RFC4/GINS2/GINS1/MCM4/MCM7/FEN1/CDC45/PCNA/CDC6/DBF4/MCM3/GINS4/PRIM2/CDT1	6.79647571934549	10.39	Reactome
R-HSA-69242	S Phase	23/269	161/10554	1.59295748877974e-11	7.23202699906001e-10	5.8240761519596e-10	1163/11065/4175/994/4171/23594/113130/84515/4174/5984/51659/9837/4173/4176/2237/8318/5111/990/4172/1019/84296/5558/81620	23	CKS1B/UBE2C/MCM6/CDC25B/MCM2/ORC6/CDCA5/MCM8/MCM5/RFC4/GINS2/GINS1/MCM4/MCM7/FEN1/CDC45/PCNA/CDC6/MCM3/CDK4/GINS4/PRIM2/CDT1	5.6048858204992	9.141	Reactome
R-HSA-5663220	RHO GTPases Activate Formins	21/269	138/10554	3.70553436923752e-11	1.57716806590672e-09	1.27012066208733e-09	9212/991/57405/55839/81930/1062/1063/4085/699/2491/1058/83540/55143/11004/57122/10403/701/332/5217/9735/5347	21	AURKB/CDC20/SPC25/CENPN/KIF18A/CENPE/CENPF/MAD2L1/BUB1/CENPI/CENPA/NUF2/CDCA8/KIF2C/NUP107/NDC80/BUB1B/BIRC5/PFN2/KNTC1/PLK1	5.97042185227089	8.802	Reactome
R-HSA-1474244	Extracellular matrix organization	30/269	301/10554	1.32972525138959e-10	5.27361444994298e-09	4.2469327280629e-09	4319/4322/3918/871/5351/3914/1300/3691/375790/4320/85301/4237/3655/1294/6696/4017/4321/4312/4318/8985/5033/1287/1284/5054/3685/3909/3371/3675/79709/9509	30	MMP10/MMP13/LAMC2/SERPINH1/PLOD1/LAMB3/COL10A1/ITGB4/AGRN/MMP11/COL27A1/MFAP2/ITGA6/COL7A1/SPP1/LOXL2/MMP12/MMP1/MMP9/PLOD3/P4HA1/COL4A5/COL4A2/SERPINE1/ITGAV/LAMA3/TNC/ITGA3/COLGALT1/ADAMTS2	3.91038545616223	8.278	Reactome
R-HSA-69239	Synthesis of DNA	19/269	119/10554	1.39390690306863e-10	5.27361444994298e-09	4.2469327280629e-09	11065/4175/4171/23594/84515/4174/5984/51659/9837/4173/4176/2237/8318/5111/990/4172/84296/5558/81620	19	UBE2C/MCM6/MCM2/ORC6/MCM8/MCM5/RFC4/GINS2/GINS1/MCM4/MCM7/FEN1/CDC45/PCNA/CDC6/MCM3/GINS4/PRIM2/CDT1	6.26428415232264	8.278	Reactome
R-HSA-2555396	Mitotic Metaphase and Anaphase	24/269	200/10554	2.38572906257892e-10	8.55095521903286e-09	6.88623180943832e-09	11065/9212/991/57405/55839/81930/1062/113130/1063/4085/699/2491/1058/4001/83540/55143/11004/57122/10403/701/332/26271/9735/5347	24	UBE2C/AURKB/CDC20/SPC25/CENPN/KIF18A/CENPE/CDCA5/CENPF/MAD2L1/BUB1/CENPI/CENPA/LMNB1/NUF2/CDCA8/KIF2C/NUP107/NDC80/BUB1B/BIRC5/FBXO5/KNTC1/PLK1	4.70810408921933	8.068	Reactome
R-HSA-68886	M Phase	34/269	393/10554	3.37634507160703e-10	1.14964549688219e-08	9.25829359109084e-09	11065/9212/991/57405/4751/55839/81930/9631/1062/113130/9493/1063/4085/699/2491/10112/1058/4001/83540/23397/55143/64151/11004/983/9133/57122/10403/701/332/26271/9735/891/9918/5347	34	UBE2C/AURKB/CDC20/SPC25/NEK2/CENPN/KIF18A/NUP155/CENPE/CDCA5/KIF23/CENPF/MAD2L1/BUB1/CENPI/KIF20A/CENPA/LMNB1/NUF2/NCAPH/CDCA8/NCAPG/KIF2C/CDK1/CCNB2/NUP107/NDC80/BUB1B/BIRC5/FBXO5/KNTC1/CCNB1/NCAPD2/PLK1	3.39430744345753	7.939	Reactome
R-HSA-68882	Mitotic Anaphase	23/269	199/10554	1.21622829562693e-09	3.94405461581876e-08	3.17621524822872e-08	11065/9212/991/57405/55839/81930/1062/113130/1063/4085/699/2491/1058/4001/83540/55143/11004/57122/10403/701/332/9735/5347	23	UBE2C/AURKB/CDC20/SPC25/CENPN/KIF18A/CENPE/CDCA5/CENPF/MAD2L1/BUB1/CENPI/CENPA/LMNB1/NUF2/CDCA8/KIF2C/NUP107/NDC80/BUB1B/BIRC5/KNTC1/PLK1	4.53460611608227	7.404	Reactome
R-HSA-69481	G2/M Checkpoints	21/269	168/10554	1.56742021897555e-09	4.85187804146523e-08	3.90730112002997e-08	4175/4171/9156/23594/641/55388/84515/1111/4174/5984/983/9133/4173/11073/4176/8318/990/10926/4172/891/672	21	MCM6/MCM2/EXO1/ORC6/BLM/MCM10/MCM8/CHEK1/MCM5/RFC4/CDK1/CCNB2/MCM4/TOPBP1/MCM7/CDC45/CDC6/DBF4/MCM3/CCNB1/BRCA1	4.9042750929368	7.314	Reactome
R-HSA-3000157	Laminin interactions	10/269	30/10554	1.87714316575333e-09	5.4794000533493e-08	4.41265542591388e-08	3918/3914/3691/3655/1294/1287/1284/3685/3909/3675	10	LAMC2/LAMB3/ITGB4/ITGA6/COL7A1/COL4A5/COL4A2/ITGAV/LAMA3/ITGA3	13.0780669144981	7.261	Reactome
R-HSA-195258	RHO GTPase Effectors	29/269	316/10554	1.93106609809667e-09	5.4794000533493e-08	4.41265542591388e-08	9212/9928/991/57405/55839/81930/10095/3984/1062/1063/4085/699/2491/1058/6242/83540/55143/11004/57122/10403/701/332/5217/9055/9735/4688/4628/128239/5347	29	AURKB/KIF14/CDC20/SPC25/CENPN/KIF18A/ARPC1B/LIMK1/CENPE/CENPF/MAD2L1/BUB1/CENPI/CENPA/RTKN/NUF2/CDCA8/KIF2C/NUP107/NDC80/BUB1B/BIRC5/PFN2/PRC1/KNTC1/NCF2/MYH10/IQGAP3/PLK1	3.6006070302574	7.261	Reactome
R-HSA-2467813	Separation of Sister Chromatids	22/269	188/10554	2.23695335935255e-09	6.09346095087634e-08	4.90716926409549e-08	11065/9212/991/57405/55839/81930/1062/113130/1063/4085/699/2491/1058/83540/55143/11004/57122/10403/701/332/9735/5347	22	UBE2C/AURKB/CDC20/SPC25/CENPN/KIF18A/CENPE/CDCA5/CENPF/MAD2L1/BUB1/CENPI/CENPA/NUF2/CDCA8/KIF2C/NUP107/NDC80/BUB1B/BIRC5/KNTC1/PLK1	4.59123625721743	7.215	Reactome
R-HSA-69002	DNA Replication Pre-Initiation	15/269	85/10554	3.06908293168575e-09	7.97356814657929e-08	6.42125203550168e-08	51053/4175/4171/23594/55388/84515/4174/4173/4176/8318/990/10926/4172/5558/81620	15	GMNN/MCM6/MCM2/ORC6/MCM10/MCM8/MCM5/MCM4/MCM7/CDC45/CDC6/DBF4/MCM3/PRIM2/CDT1	6.92368248414607	7.098	Reactome
R-HSA-2022090	Assembly of collagen fibrils and other multimeric structures	13/269	61/10554	3.16132657793893e-09	7.97356814657929e-08	6.42125203550168e-08	4322/3918/3914/1300/3691/85301/3655/1294/4017/4318/1287/1284/3909	13	MMP13/LAMC2/LAMB3/COL10A1/ITGB4/COL27A1/ITGA6/COL7A1/LOXL2/MMP9/COL4A5/COL4A2/LAMA3	8.36138704369553	7.098	Reactome
R-HSA-539107	Activation of E2F1 target genes at G1/S	9/269	28/10554	1.79522178334794e-08	4.21567598089637e-07	3.39495662114075e-07	983/7083/8318/5111/990/26271/6241/7298/81620	9	CDK1/TK1/CDC45/PCNA/CDC6/FBXO5/RRM2/TYMS/CDT1	12.6109930961232	6.375	Reactome
R-HSA-69205	G1/S-Specific Transcription	9/269	28/10554	1.79522178334794e-08	4.21567598089637e-07	3.39495662114075e-07	983/7083/8318/5111/990/26271/6241/7298/81620	9	CDK1/TK1/CDC45/PCNA/CDC6/FBXO5/RRM2/TYMS/CDT1	12.6109930961232	6.375	Reactome
R-HSA-2514853	Condensation of Prometaphase Chromosomes	6/269	11/10554	1.07649233845235e-07	2.36481058866467e-06	1.90442277872215e-06	23397/64151/983/9133/891/9918	6	NCAPH/NCAPG/CDK1/CCNB2/CCNB1/NCAPD2	21.4004731328151	5.626	Reactome
R-HSA-446107	Type I hemidesmosome assembly	6/269	11/10554	1.07649233845235e-07	2.36481058866467e-06	1.90442277872215e-06	3918/3914/3691/3655/3909/3861	6	LAMC2/LAMB3/ITGB4/ITGA6/LAMA3/KRT14	21.4004731328151	5.626	Reactome
R-HSA-3000171	Non-integrin membrane-ECM interactions	11/269	59/10554	2.2746305030545e-07	4.84069803931286e-06	3.89829767135327e-06	3918/3914/1300/3691/375790/3655/1287/1284/3685/3909/3371	11	LAMC2/LAMB3/COL10A1/ITGB4/AGRN/ITGA6/COL4A5/COL4A2/ITGAV/LAMA3/TNC	7.31485098607523	5.315	Reactome
R-HSA-194315	Signaling by Rho GTPases	31/269	444/10554	3.12625078095932e-07	6.45144479343423e-06	5.19545983055759e-06	9212/9928/991/1894/57405/55839/81930/10095/3984/1062/1063/4085/699/2491/1058/6242/83540/55143/55789/11004/57122/10403/701/332/5217/9055/9735/4688/4628/128239/5347	31	AURKB/KIF14/CDC20/ECT2/SPC25/CENPN/KIF18A/ARPC1B/LIMK1/CENPE/CENPF/MAD2L1/BUB1/CENPI/CENPA/RTKN/NUF2/CDCA8/DEPDC1B/KIF2C/NUP107/NDC80/BUB1B/BIRC5/PFN2/PRC1/KNTC1/NCF2/MYH10/IQGAP3/PLK1	2.73932482668542	5.19	Reactome
R-HSA-1650814	Collagen biosynthesis and modifying enzymes	11/269	67/10554	8.71791433106877e-07	1.74614695866407e-05	1.40620228064608e-05	871/5351/1300/85301/1294/8985/5033/1287/1284/79709/9509	11	SERPINH1/PLOD1/COL10A1/COL27A1/COL7A1/PLOD3/P4HA1/COL4A5/COL4A2/COLGALT1/ADAMTS2	6.44143594296177	4.758	Reactome
R-HSA-68867	Assembly of the pre-replicative complex	11/269	68/10554	1.01681838766881e-06	1.97843806286417e-05	1.59327031571564e-05	51053/4175/4171/23594/84515/4174/4173/4176/990/4172/81620	11	GMNN/MCM6/MCM2/ORC6/MCM8/MCM5/MCM4/MCM7/CDC6/MCM3/CDT1	6.34670894380057	4.704	Reactome
R-HSA-2214320	Anchoring fibril formation	6/269	15/10554	1.06988570668657e-06	2.0238671284821e-05	1.62985512626814e-05	3918/3914/1294/1287/1284/3909	6	LAMC2/LAMB3/COL7A1/COL4A5/COL4A2/LAMA3	15.6936802973978	4.694	Reactome
R-HSA-156711	Polo-like kinase mediated events	6/269	16/10554	1.67535798215396e-06	3.08356428607256e-05	2.48324753542593e-05	4605/1063/2305/9133/891/5347	6	MYBL2/CENPF/FOXM1/CCNB2/CCNB1/PLK1	14.7128252788104	4.511	Reactome
R-HSA-210991	Basigin interactions	7/269	25/10554	2.09663028170449e-06	3.75738216273883e-05	3.02588470018847e-05	3655/483/4312/6520/6566/23657/3675	7	ITGA6/ATP1B3/MMP1/SLC3A2/SLC16A1/SLC7A11/ITGA3	10.9855762081784	4.425	Reactome
R-HSA-1442490	Collagen degradation	10/269	64/10554	4.40587443635096e-06	7.69333459270514e-05	6.19557511832348e-05	4319/4322/1300/4320/1294/4321/4312/4318/1287/1284	10	MMP10/MMP13/COL10A1/MMP11/COL7A1/MMP12/MMP1/MMP9/COL4A5/COL4A2	6.130343866171	4.114	Reactome
R-HSA-5693579	Homologous DNA Pairing and Strand Exchange	8/269	42/10554	8.93050690551597e-06	0.000152041880066409	0.000122441949941416	9156/641/10635/1111/5984/11073/5888/672	8	EXO1/BLM/RAD51AP1/CHEK1/RFC4/TOPBP1/RAD51/BRCA1	7.47318109399894	3.818	Reactome
R-HSA-174143	APC/C-mediated degradation of cell cycle proteins	11/269	86/10554	1.08130714875228e-05	0.000175326230547691	0.000141193239223042	11065/9212/991/4751/6790/4085/983/701/26271/891/5347	11	UBE2C/AURKB/CDC20/NEK2/AURKA/MAD2L1/CDK1/BUB1B/FBXO5/CCNB1/PLK1	5.01832800207487	3.756	Reactome
R-HSA-453276	Regulation of mitotic cell cycle	11/269	86/10554	1.08130714875228e-05	0.000175326230547691	0.000141193239223042	11065/9212/991/4751/6790/4085/983/701/26271/891/5347	11	UBE2C/AURKB/CDC20/NEK2/AURKA/MAD2L1/CDK1/BUB1B/FBXO5/CCNB1/PLK1	5.01832800207487	3.756	Reactome
R-HSA-68949	Orc1 removal from chromatin	10/269	71/10554	1.14796133068117e-05	0.000181805038649738	0.000146410735198259	4175/4171/23594/84515/4174/4173/4176/990/4172/81620	10	MCM6/MCM2/ORC6/MCM8/MCM5/MCM4/MCM7/CDC6/MCM3/CDT1	5.52594376668936	3.74	Reactome
R-HSA-4615885	SUMOylation of DNA replication proteins	8/269	44/10554	1.28307143725494e-05	0.00019449659055946	0.000156631460980723	9212/9631/6790/55143/7153/57122/332/5111	8	AURKB/NUP155/AURKA/CDCA8/TOP2A/NUP107/BIRC5/PCNA	7.13349104427171	3.711	Reactome
R-HSA-1474228	Degradation of the extracellular matrix	14/269	140/10554	1.28521976140612e-05	0.00019449659055946	0.000156631460980723	4319/4322/3918/3914/1300/4320/1294/6696/4321/4312/4318/1287/1284/3909	14	MMP10/MMP13/LAMC2/LAMB3/COL10A1/MMP11/COL7A1/SPP1/MMP12/MMP1/MMP9/COL4A5/COL4A2/LAMA3	3.92342007434944	3.711	Reactome
R-HSA-69052	Switching of origins to a post-replicative state	11/269	90/10554	1.68049608166288e-05	0.000248786485133135	0.000200352050010609	11065/4175/4171/23594/84515/4174/4173/4176/990/4172/81620	11	UBE2C/MCM6/MCM2/ORC6/MCM8/MCM5/MCM4/MCM7/CDC6/MCM3/CDT1	4.79529120198265	3.604	Reactome
R-HSA-69273	Cyclin A/B1/B2 associated events during G2/M transition	6/269	25/10554	3.05368024597551e-05	0.000442458776065814	0.000356319688276202	994/2305/983/9133/891/5347	6	CDC25B/FOXM1/CDK1/CCNB2/CCNB1/PLK1	9.41620817843866	3.354	Reactome
R-HSA-5685942	HDR through Homologous Recombination (HRR)	9/269	67/10554	4.65720850648942e-05	0.000660741456858187	0.000532106498219515	9156/641/10635/1111/5984/11073/5888/5111/672	9	EXO1/BLM/RAD51AP1/CHEK1/RFC4/TOPBP1/RAD51/PCNA/BRCA1	5.27026577151418	3.18	Reactome
R-HSA-5693616	Presynaptic phase of homologous DNA pairing and strand exchange	7/269	39/10554	4.9427196867683e-05	0.000686937164630452	0.00055320235377149	9156/641/1111/5984/11073/5888/672	7	EXO1/BLM/CHEK1/RFC4/TOPBP1/RAD51/BRCA1	7.04203603088362	3.163	Reactome
R-HSA-216083	Integrin cell surface interactions	10/269	85/10554	5.68658719279886e-05	0.000774513175659205	0.000623728826831202	1300/375790/3655/1294/6696/1287/1284/3685/3371/3675	10	COL10A1/AGRN/ITGA6/COL7A1/SPP1/COL4A5/COL4A2/ITGAV/TNC/ITGA3	4.61578832276405	3.111	Reactome
R-HSA-983189	Kinesins	8/269	57/10554	8.98284348176332e-05	0.00119947380609428	0.000965956956449678	24137/146909/81930/1062/9493/56992/10112/11004	8	KIF4A/KIF18B/KIF18A/CENPE/KIF23/KIF15/KIF20A/KIF2C	5.50655449031501	2.921	Reactome
R-HSA-8874081	MET activates PTK2 signaling	6/269	30/10554	9.19829414911499e-05	0.00120462275298987	0.000970103492244718	3918/3914/85301/4233/3909/3675	6	LAMC2/LAMB3/COL27A1/MET/LAMA3/ITGA3	7.84684014869888	2.919	Reactome
R-HSA-73886	Chromosome Maintenance	11/269	110/10554	0.000109838973917509	0.00141132719316648	0.00113656614520402	8607/55839/2491/1058/5984/55355/2237/5111/11339/5558/387103	11	RUVBL1/CENPN/CENPI/CENPA/RFC4/HJURP/FEN1/PCNA/OIP5/PRIM2/CENPW	3.92342007434944	2.85	Reactome
R-HSA-6804756	Regulation of TP53 Activity through Phosphorylation	10/269	92/10554	0.000112062853612312	0.00141323709833304	0.0011381042247956	22974/9212/9156/6790/641/1111/5984/11073/9891/672	10	TPX2/AURKB/EXO1/AURKA/BLM/CHEK1/RFC4/TOPBP1/NUAK1/BRCA1	4.26458703733635	2.85	Reactome
R-HSA-113510	E2F mediated regulation of DNA replication	5/269	22/10554	0.000191183004903295	0.00236719320616625	0.00190634154171515	23594/84515/983/891/5558	5	ORC6/MCM8/CDK1/CCNB1/PRIM2	8.91686380533964	2.626	Reactome
R-HSA-2980766	Nuclear Envelope Breakdown	7/269	51/10554	0.000286657119120515	0.00348595532359055	0.00280729998236445	9631/4001/983/9133/57122/891/5347	7	NUP155/LMNB1/CDK1/CCNB2/NUP107/CCNB1/PLK1	5.38508637655806	2.458	Reactome
R-HSA-5685938	HDR through Single Strand Annealing (SSA)	6/269	37/10554	0.000310105026466137	0.00370493900041121	0.00298365131650706	9156/641/5984/11073/5888/672	6	EXO1/BLM/RFC4/TOPBP1/RAD51/BRCA1	6.36230282326937	2.431	Reactome
R-HSA-162658	Golgi Cisternae Pericentriolar Stack Reorganization	4/269	14/10554	0.000337635878104437	0.00396431091360554	0.00319252799441764	983/9133/891/5347	4	CDK1/CCNB2/CCNB1/PLK1	11.2097716409984	2.402	Reactome
R-HSA-909733	Interferon alpha/beta signaling	8/269	69/10554	0.000349228791934544	0.00403092893741398	0.00324617663867792	9636/2537/3430/91543/3437/3434/684/11274	8	ISG15/IFI6/IFI35/RSAD2/IFIT3/IFIT1/BST2/USP18	4.54889283982544	2.395	Reactome
R-HSA-179409	APC-Cdc20 mediated degradation of Nek2A	5/269	25/10554	0.000362317265618694	0.00411230096477218	0.00331170693661999	11065/991/4751/4085/701	5	UBE2C/CDC20/NEK2/MAD2L1/BUB1B	7.84684014869888	2.386	Reactome
R-HSA-1169408	ISG15 antiviral mechanism	8/269	71/10554	0.000425297584884675	0.00474799434928629	0.00382364178990364	9631/3838/57122/9636/5610/51191/3434/11274	8	NUP155/KPNA2/NUP107/ISG15/EIF2AK2/HERC5/IFIT1/USP18	4.42075501335148	2.323	Reactome
R-HSA-5693554	Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	5/269	26/10554	0.000439331915730778	0.00482556507439774	0.00388611083354389	9156/641/10635/5888/672	5	EXO1/BLM/RAD51AP1/RAD51/BRCA1	7.54503860451816	2.316	Reactome
R-HSA-73894	DNA Repair	19/269	316/10554	0.000463315441083743	0.00500821929171475	0.00403320542697795	29089/8607/9156/641/10635/1111/51514/5984/8914/2956/86/3838/11073/2237/5888/55215/5111/9636/672	19	UBE2T/RUVBL1/EXO1/BLM/RAD51AP1/CHEK1/DTL/RFC4/TIMELESS/MSH6/ACTL6A/KPNA2/TOPBP1/FEN1/RAD51/FANCI/PCNA/ISG15/BRCA1	2.35901839913416	2.3	Reactome
R-HSA-913531	Interferon Signaling	14/269	197/10554	0.000513500133263259	0.00546396235550437	0.00440022318141707	9631/3838/57122/9636/5610/51191/2537/3430/91543/3437/3434/684/2633/11274	14	NUP155/KPNA2/NUP107/ISG15/EIF2AK2/HERC5/IFI6/IFI35/RSAD2/IFIT3/IFIT1/BST2/GBP1/USP18	2.78821731172042	2.262	Reactome
R-HSA-1538133	G0 and Early G1	5/269	27/10554	0.00052806688044613	0.00553251608590483	0.00445543068360216	4605/7153/983/5111/990	5	MYBL2/TOP2A/CDK1/PCNA/CDC6	7.26559273027675	2.257	Reactome
R-HSA-8875878	MET promotes cell motility	6/269	41/10554	0.00055075833849299	0.00568282467445039	0.00457647678396886	3918/3914/85301/4233/3909/3675	6	LAMC2/LAMB3/COL27A1/MET/LAMA3/ITGA3	5.7415903527065	2.245	Reactome
R-HSA-176814	Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	8/269	76/10554	0.000675581908620503	0.00686673551896362	0.00552990061887325	11065/991/4751/4085/983/701/891/5347	8	UBE2C/CDC20/NEK2/MAD2L1/CDK1/BUB1B/CCNB1/PLK1	4.12991586773625	2.163	Reactome
R-HSA-3108232	SUMO E3 ligases SUMOylate target proteins	13/269	181/10554	0.000732569192362585	0.00733646499998412	0.00590818187648463	9212/1789/9631/6790/641/1786/55143/7153/57122/332/5111/84733/672	13	AURKB/DNMT3B/NUP155/AURKA/BLM/DNMT1/CDCA8/TOP2A/NUP107/BIRC5/PCNA/CBX2/BRCA1	2.81792602025098	2.135	Reactome
R-HSA-5693538	Homology Directed Repair	11/269	138/10554	0.000791378076879346	0.00771261872746046	0.00621110496484566	9156/641/10635/1111/5984/8914/11073/2237/5888/5111/672	11	EXO1/BLM/RAD51AP1/CHEK1/RFC4/TIMELESS/TOPBP1/FEN1/RAD51/PCNA/BRCA1	3.12736382737999	2.113	Reactome
R-HSA-5633007	Regulation of TP53 Activity	12/269	160/10554	0.000796577657698352	0.00771261872746046	0.00621110496484566	22974/9212/9156/6790/641/1111/5984/983/11073/9891/8626/672	12	TPX2/AURKB/EXO1/AURKA/BLM/CHEK1/RFC4/CDK1/TOPBP1/NUAK1/TP63/BRCA1	2.94256505576208	2.113	Reactome
R-HSA-1169410	Antiviral mechanism by IFN-stimulated genes	8/269	78/10554	0.00080410562356783	0.00771261872746046	0.00621110496484566	9631/3838/57122/9636/5610/51191/3434/11274	8	NUP155/KPNA2/NUP107/ISG15/EIF2AK2/HERC5/IFIT1/USP18	4.02402058907635	2.113	Reactome
R-HSA-180786	Extension of Telomeres	5/269	30/10554	0.000875760225041493	0.00828323212851746	0.00667062978430728	8607/5984/2237/5111/5558	5	RUVBL1/RFC4/FEN1/PCNA/PRIM2	6.53903345724907	2.082	Reactome
R-HSA-176408	Regulation of APC/C activators between G1/S and early anaphase	8/269	80/10554	0.00095158456305361	0.00876424158959402	0.0070579950045266	11065/991/4085/983/701/26271/891/5347	8	UBE2C/CDC20/MAD2L1/CDK1/BUB1B/FBXO5/CCNB1/PLK1	3.92342007434944	2.057	Reactome
R-HSA-6804114	TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	4/269	18/10554	0.000952355180073359	0.00876424158959402	0.0070579950045266	6790/983/5111/891	4	AURKA/CDK1/PCNA/CCNB1	8.71871127633209	2.057	Reactome
R-HSA-2990846	SUMOylation	13/269	187/10554	0.000992023387248148	0.00900757235621319	0.00725395347026365	9212/1789/9631/6790/641/1786/55143/7153/57122/332/5111/84733/672	13	AURKB/DNMT3B/NUP155/AURKA/BLM/DNMT1/CDCA8/TOP2A/NUP107/BIRC5/PCNA/CBX2/BRCA1	2.7275112816333	2.045	Reactome
R-HSA-3700989	Transcriptional Regulation by TP53	20/269	365/10554	0.00106082069446975	0.00950551174913028	0.00765495265676927	22974/9212/637/9156/6790/641/1111/5984/983/11073/332/55215/5111/7296/9891/891/3486/8626/672/144455	20	TPX2/AURKB/BID/EXO1/AURKA/BLM/CHEK1/RFC4/CDK1/TOPBP1/BIRC5/FANCI/PCNA/TXNRD1/NUAK1/CCNB1/IGFBP3/TP63/BRCA1/E2F7	2.14981921882161	2.022	Reactome
R-HSA-5693532	DNA Double-Strand Break Repair	12/269	166/10554	0.00109996904879672	0.00972829769130601	0.00783436602082144	9156/641/10635/1111/5984/8914/3838/11073/2237/5888/5111/672	12	EXO1/BLM/RAD51AP1/CHEK1/RFC4/TIMELESS/KPNA2/TOPBP1/FEN1/RAD51/PCNA/BRCA1	2.83620728266225	2.012	Reactome
R-HSA-176412	Phosphorylation of the APC/C	4/269	19/10554	0.00118234826107979	0.010322809817889	0.00831313689639099	11065/983/891/5347	4	UBE2C/CDK1/CCNB1/PLK1	8.25983173547251	1.986	Reactome
R-HSA-381426	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	10/269	125/10554	0.00132203845516876	0.0113963061768345	0.00917764204054528	54972/6696/8614/4312/11098/3486/3956/8542/3371/255738	10	TMEM132A/SPP1/STC2/MMP1/PRSS23/IGFBP3/LGALS1/APOL1/TNC/PCSK9	3.13873605947955	1.943	Reactome
R-HSA-1592389	Activation of Matrix Metalloproteinases	5/269	33/10554	0.00137045123573926	0.0115219418708449	0.00927881863314044	4319/4322/4320/4312/4318	5	MMP10/MMP13/MMP11/MMP1/MMP9	5.94457587022643	1.938	Reactome
R-HSA-5693568	Resolution of D-loop Structures through Holliday Junction Intermediates	5/269	33/10554	0.00137045123573926	0.0115219418708449	0.00927881863314044	9156/641/10635/5888/672	5	EXO1/BLM/RAD51AP1/RAD51/BRCA1	5.94457587022643	1.938	Reactome
R-HSA-69275	G2/M Transition	13/269	194/10554	0.00138792889402381	0.0115265802052465	0.00928255396388195	4605/22974/994/4751/1063/6790/2305/983/9133/79866/3161/891/5347	13	MYBL2/TPX2/CDC25B/NEK2/CENPF/AURKA/FOXM1/CDK1/CCNB2/BORA/HMMR/CCNB1/PLK1	2.62909592611045	1.938	Reactome
R-HSA-141405	Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	4/269	20/10554	0.00144859499753438	0.0116058022743637	0.00934635286334877	11065/991/4085/701	4	UBE2C/CDC20/MAD2L1/BUB1B	7.84684014869888	1.935	Reactome
R-HSA-141430	Inactivation of APC/C via direct inhibition of the APC/C complex	4/269	20/10554	0.00144859499753438	0.0116058022743637	0.00934635286334877	11065/991/4085/701	4	UBE2C/CDC20/MAD2L1/BUB1B	7.84684014869888	1.935	Reactome
R-HSA-69186	Lagging Strand Synthesis	4/269	20/10554	0.00144859499753438	0.0116058022743637	0.00934635286334877	5984/2237/5111/5558	4	RFC4/FEN1/PCNA/PRIM2	7.84684014869888	1.935	Reactome
R-HSA-453274	Mitotic G2-G2/M phases	13/269	196/10554	0.00152258852817709	0.0120567766010302	0.00970953027148428	4605/22974/994/4751/1063/6790/2305/983/9133/79866/3161/891/5347	13	MYBL2/TPX2/CDC25B/NEK2/CENPF/AURKA/FOXM1/CDK1/CCNB2/BORA/HMMR/CCNB1/PLK1	2.60226841666034	1.919	Reactome
R-HSA-3301854	Nuclear Pore Complex (NPC) Disassembly	5/269	34/10554	0.00157375941920091	0.0121787518690434	0.00980775905985258	9631/983/9133/57122/891	5	NUP155/CDK1/CCNB2/NUP107/CCNB1	5.76973540345506	1.914	Reactome
R-HSA-5693537	Resolution of D-Loop Structures	5/269	34/10554	0.00157375941920091	0.0121787518690434	0.00980775905985258	9156/641/10635/5888/672	5	EXO1/BLM/RAD51AP1/RAD51/BRCA1	5.76973540345506	1.914	Reactome
R-HSA-8957275	Post-translational protein phosphorylation	9/269	108/10554	0.00172021952143627	0.0131625785853719	0.0106000516932974	54972/6696/8614/11098/3486/3956/8542/3371/255738	9	TMEM132A/SPP1/STC2/PRSS23/IGFBP3/LGALS1/APOL1/TNC/PCSK9	3.26951672862454	1.881	Reactome
R-HSA-8953750	Transcriptional Regulation by E2F6	5/269	35/10554	0.00179839305927002	0.0136078408151432	0.0109586290512243	1111/11335/5888/6241/672	5	CHEK1/CBX3/RAD51/RRM2/BRCA1	5.6048858204992	1.866	Reactome
R-HSA-5693567	HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	10/269	132/10554	0.00199151868800886	0.0149035629289454	0.0120020964309152	9156/641/10635/1111/5984/8914/11073/5888/5111/672	10	EXO1/BLM/RAD51AP1/CHEK1/RFC4/TIMELESS/TOPBP1/RAD51/PCNA/BRCA1	2.97228793511321	1.827	Reactome
R-HSA-446728	Cell junction organization	8/269	91/10554	0.00219450814135297	0.0162441309158845	0.0130816789661888	3918/3914/3691/3655/1001/3909/3861/221935	8	LAMC2/LAMB3/ITGB4/ITGA6/CDH3/LAMA3/KRT14/SDK1	3.44916050492259	1.789	Reactome
R-HSA-68689	CDC6 association with the ORC:origin complex	3/269	11/10554	0.0023212290283218	0.0169973867557758	0.013688288893669	23594/84515/990	3	ORC6/MCM8/CDC6	10.7002365664076	1.77	Reactome
R-HSA-174048	APC/C:Cdc20 mediated degradation of Cyclin B	4/269	23/10554	0.00249322424032253	0.0180626139112728	0.0145461347055771	11065/991/983/891	4	UBE2C/CDC20/CDK1/CCNB1	6.82333925973816	1.743	Reactome
R-HSA-202733	Cell surface interactions at the vascular wall	10/269	137/10554	0.00261954551272749	0.0187780052017623	0.0151222516579614	3655/4072/483/4312/6520/6566/10544/3685/23657/3675	10	ITGA6/EPCAM/ATP1B3/MMP1/SLC3A2/SLC16A1/PROCR/ITGAV/SLC7A11/ITGA3	2.86381027324777	1.726	Reactome
R-HSA-606279	Deposition of new CENPA-containing nucleosomes at the centromere	7/269	74/10554	0.00271159551092122	0.0190370777622408	0.0153308872619637	8607/55839/2491/1058/55355/11339/387103	7	RUVBL1/CENPN/CENPI/CENPA/HJURP/OIP5/CENPW	3.7113433135738	1.72	Reactome
R-HSA-774815	Nucleosome assembly	7/269	74/10554	0.00271159551092122	0.0190370777622408	0.0153308872619637	8607/55839/2491/1058/55355/11339/387103	7	RUVBL1/CENPN/CENPI/CENPA/HJURP/OIP5/CENPW	3.7113433135738	1.72	Reactome
R-HSA-69473	G2/M DNA damage checkpoint	8/269	95/10554	0.00287688582806629	0.0197976329944342	0.0159433755160371	9156/641/1111/5984/983/11073/891/672	8	EXO1/BLM/CHEK1/RFC4/CDK1/TOPBP1/CCNB1/BRCA1	3.303932694189	1.703	Reactome
R-HSA-176409	APC/C:Cdc20 mediated degradation of mitotic proteins	7/269	75/10554	0.0029271287250053	0.0197976329944342	0.0159433755160371	11065/991/4751/4085/983/701/891	7	UBE2C/CDC20/NEK2/MAD2L1/CDK1/BUB1B/CCNB1	3.66185873605948	1.703	Reactome
R-HSA-174417	Telomere C-strand (Lagging Strand) Synthesis	4/269	24/10554	0.00293267685378965	0.0197976329944342	0.0159433755160371	5984/2237/5111/5558	4	RFC4/FEN1/PCNA/PRIM2	6.53903345724907	1.703	Reactome
R-HSA-168276	NS1 Mediated Effects on Host Pathways	5/269	39/10554	0.00293621282296307	0.0197976329944342	0.0159433755160371	9631/3838/57122/9636/5610	5	NUP155/KPNA2/NUP107/ISG15/EIF2AK2	5.03002573634544	1.703	Reactome
R-HSA-3000178	ECM proteoglycans	7/269	76/10554	0.00315554651797187	0.0210679135170475	0.016966354343275	375790/1287/1284/5054/3685/3909/3371	7	AGRN/COL4A5/COL4A2/SERPINE1/ITGAV/LAMA3/TNC	3.61367638426922	1.676	Reactome
R-HSA-6811434	COPI-dependent Golgi-to-ER retrograde traffic	8/269	97/10554	0.00327491999284292	0.0216526263604469	0.0174372336869817	24137/146909/81930/1062/9493/56992/10112/11004	8	KIF4A/KIF18B/KIF18A/CENPE/KIF23/KIF15/KIF20A/KIF2C	3.23581037059748	1.664	Reactome
R-HSA-168253	Host Interactions with Influenza Factors	5/269	41/10554	0.00366710201137549	0.0240124660552568	0.0193376533190954	9631/3838/57122/9636/5610	5	NUP155/KPNA2/NUP107/ISG15/EIF2AK2	4.78465862725542	1.62	Reactome
R-HSA-75035	Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	3/269	13/10554	0.00387431265790603	0.0248906313210755	0.0200448549629498	1111/983/891	3	CHEK1/CDK1/CCNB1	9.05404632542179	1.604	Reactome
R-HSA-75205	Dissolution of Fibrin Clot	3/269	13/10554	0.00387431265790603	0.0248906313210755	0.0200448549629498	5328/5329/5054	3	PLAU/PLAUR/SERPINE1	9.05404632542179	1.604	Reactome
R-HSA-1630316	Glycosaminoglycan metabolism	9/269	124/10554	0.00439117896432176	0.0279475969598422	0.0225066821486634	375790/9435/10057/51363/3161/8534/56548/3037/50515	9	AGRN/CHST2/ABCC5/CHST15/HMMR/CHST1/CHST7/HAS2/CHST11	2.8476436023504	1.554	Reactome
R-HSA-3000170	Syndecan interactions	4/269	27/10554	0.00456228303427528	0.0287677291327914	0.0231671487413004	3691/3655/3685/3371	4	ITGB4/ITGA6/ITGAV/TNC	5.8124741842214	1.541	Reactome
R-HSA-174411	Polymerase switching on the C-strand of the telomere	3/269	14/10554	0.00483886087057919	0.0289058267795125	0.0232783611594807	5984/5111/5558	3	RFC4/PCNA/PRIM2	8.40732873074881	1.539	Reactome
R-HSA-5358565	Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	3/269	14/10554	0.00483886087057919	0.0289058267795125	0.0232783611594807	9156/2956/5111	3	EXO1/MSH6/PCNA	8.40732873074881	1.539	Reactome
R-HSA-68884	Mitotic Telophase/Cytokinesis	3/269	14/10554	0.00483886087057919	0.0289058267795125	0.0232783611594807	9493/10112/5347	3	KIF23/KIF20A/PLK1	8.40732873074881	1.539	Reactome
R-HSA-69091	Polymerase switching	3/269	14/10554	0.00483886087057919	0.0289058267795125	0.0232783611594807	5984/5111/5558	3	RFC4/PCNA/PRIM2	8.40732873074881	1.539	Reactome
R-HSA-69109	Leading Strand Synthesis	3/269	14/10554	0.00483886087057919	0.0289058267795125	0.0232783611594807	5984/5111/5558	3	RFC4/PCNA/PRIM2	8.40732873074881	1.539	Reactome
R-HSA-69166	Removal of the Flap Intermediate	3/269	14/10554	0.00483886087057919	0.0289058267795125	0.0232783611594807	2237/5111/5558	3	FEN1/PCNA/PRIM2	8.40732873074881	1.539	Reactome
R-HSA-8948216	Collagen chain trimerization	5/269	44/10554	0.00499551993266959	0.0295821658621565	0.0238230286949278	1300/85301/1294/1287/1284	5	COL10A1/COL27A1/COL7A1/COL4A5/COL4A2	4.45843190266982	1.529	Reactome
R-HSA-4419969	Depolymerisation of the Nuclear Lamina	3/269	15/10554	0.00593576754924819	0.0342564211952375	0.0275872871825005	4001/983/891	3	LMNB1/CDK1/CCNB1	7.84684014869888	1.465	Reactome
R-HSA-5358508	Mismatch Repair	3/269	15/10554	0.00593576754924819	0.0342564211952375	0.0275872871825005	9156/2956/5111	3	EXO1/MSH6/PCNA	7.84684014869888	1.465	Reactome
R-HSA-69183	Processive synthesis on the lagging strand	3/269	15/10554	0.00593576754924819	0.0342564211952375	0.0275872871825005	2237/5111/5558	3	FEN1/PCNA/PRIM2	7.84684014869888	1.465	Reactome
R-HSA-2565942	Regulation of PLK1 Activity at G2/M Transition	7/269	88/10554	0.00708535172301959	0.0405472649023222	0.032653412186583	4751/6790/983/9133/79866/891/5347	7	NEK2/AURKA/CDK1/CCNB2/BORA/CCNB1/PLK1	3.12090233186887	1.392	Reactome
R-HSA-380108	Chemokine receptors bind chemokines	5/269	48/10554	0.00725428845577535	0.0411680869865251	0.0331533709250786	3576/6375/2919/3627/6364	5	CXCL8/XCL1/CXCL1/CXCL10/CCL20	4.08689591078067	1.385	Reactome
R-HSA-6791312	TP53 Regulates Transcription of Cell Cycle Genes	5/269	49/10554	0.0079144342124985	0.0445432206505081	0.0358714243124117	6790/983/5111/891/144455	5	AURKA/CDK1/PCNA/CCNB1/E2F7	4.00348987178515	1.351	Reactome
R-HSA-2142845	Hyaluronan metabolism	3/269	17/10554	0.00854385612457146	0.0473037887872615	0.0380945574745548	10057/3161/3037	3	ABCC5/HMMR/HAS2	6.92368248414607	1.325	Reactome
R-HSA-4655427	SUMOylation of DNA methylation proteins	3/269	17/10554	0.00854385612457146	0.0473037887872615	0.0380945574745548	1789/1786/84733	3	DNMT3B/DNMT1/CBX2	6.92368248414607	1.325	Reactome