| Full name: sterol-C5-desaturase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q23.3-q24.1 | ||
| Entrez ID: 6309 | HGNC ID: HGNC:10547 | Ensembl Gene: ENSG00000109929 | OMIM ID: 602286 |
Screen Evidence:
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Expression of SC5D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SC5D | 6309 | 211423_s_at | -0.7883 | 0.2506 | |
| GSE20347 | SC5D | 6309 | 211423_s_at | -0.9554 | 0.0003 | |
| GSE23400 | SC5D | 6309 | 211423_s_at | -0.3653 | 0.0083 | |
| GSE26886 | SC5D | 6309 | 211423_s_at | -0.6108 | 0.0491 | |
| GSE29001 | SC5D | 6309 | 211423_s_at | -0.9315 | 0.0857 | |
| GSE38129 | SC5D | 6309 | 211423_s_at | -0.4945 | 0.0581 | |
| GSE45670 | SC5D | 6309 | 211423_s_at | -0.1484 | 0.5994 | |
| GSE63941 | SC5D | 6309 | 211423_s_at | -0.4601 | 0.4248 | |
| GSE77861 | SC5D | 6309 | 211423_s_at | -0.0254 | 0.9550 | |
| SRP007169 | SC5D | 6309 | RNAseq | -0.9040 | 0.0979 | |
| SRP008496 | SC5D | 6309 | RNAseq | -0.6935 | 0.0277 | |
| SRP064894 | SC5D | 6309 | RNAseq | -0.9432 | 0.0013 | |
| SRP133303 | SC5D | 6309 | RNAseq | 0.1819 | 0.6358 | |
| SRP159526 | SC5D | 6309 | RNAseq | -0.3198 | 0.5828 | |
| SRP193095 | SC5D | 6309 | RNAseq | -0.9690 | 0.0000 | |
| SRP219564 | SC5D | 6309 | RNAseq | -1.4856 | 0.0030 |
Upregulated datasets: 0; Downregulated datasets: 1.
Copy number change of SC5D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SC5D | 6309 | 0 | 13 | 17 | |
| GSE20123 | SC5D | 6309 | 0 | 13 | 17 | |
| GSE43470 | SC5D | 6309 | 2 | 7 | 34 | |
| GSE46452 | SC5D | 6309 | 3 | 26 | 30 | |
| GSE47630 | SC5D | 6309 | 2 | 19 | 19 | |
| GSE54993 | SC5D | 6309 | 10 | 0 | 60 | |
| GSE54994 | SC5D | 6309 | 5 | 19 | 29 | |
| GSE60625 | SC5D | 6309 | 0 | 3 | 8 | |
| GSE74703 | SC5D | 6309 | 1 | 5 | 30 | |
| GSE74704 | SC5D | 6309 | 0 | 9 | 11 | |
| TCGA | SC5D | 6309 | 5 | 50 | 41 |
Total number of gains: 28; Total number of losses: 164; Total Number of normals: 296.
Somatic mutations of SC5D:
Generating mutation plots.
Highly correlated genes for SC5D:
Showing top 20/465 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SC5D | HOMER2 | 0.692131 | 3 | 0 | 3 |
| SC5D | TRAPPC13 | 0.689126 | 3 | 0 | 3 |
| SC5D | DMXL1 | 0.686131 | 4 | 0 | 3 |
| SC5D | ZBTB43 | 0.674761 | 4 | 0 | 4 |
| SC5D | BLVRA | 0.672062 | 4 | 0 | 3 |
| SC5D | ERP44 | 0.670629 | 4 | 0 | 4 |
| SC5D | CLINT1 | 0.665771 | 6 | 0 | 5 |
| SC5D | COMMD8 | 0.659019 | 5 | 0 | 4 |
| SC5D | SDHD | 0.655688 | 8 | 0 | 8 |
| SC5D | SAR1B | 0.647428 | 5 | 0 | 4 |
| SC5D | SLC35A3 | 0.647029 | 5 | 0 | 4 |
| SC5D | RTCA | 0.645734 | 5 | 0 | 5 |
| SC5D | ALDH3B2 | 0.645625 | 5 | 0 | 4 |
| SC5D | UEVLD | 0.640794 | 4 | 0 | 4 |
| SC5D | HSD17B4 | 0.640736 | 5 | 0 | 4 |
| SC5D | AGGF1 | 0.639043 | 4 | 0 | 4 |
| SC5D | DYNLT3 | 0.638419 | 7 | 0 | 6 |
| SC5D | TWF1 | 0.638237 | 5 | 0 | 5 |
| SC5D | OSTF1 | 0.638076 | 7 | 0 | 6 |
| SC5D | CLTB | 0.637843 | 4 | 0 | 3 |
For details and further investigation, click here
