| Gene/Event | Cancer Type | Patient | Variant | Mutation Level |
|---|---|---|---|---|
| POLE | Bladder Cancer | p076_DFCI-10 | p.E2085Q | Trunk mutation |
| POLE | Bladder Cancer | p076_FCCC-008 | p.Q2061E | Trunk mutation |
| POLE | Bladder Cancer | p076_FCCC-017 | p.D16V | Private mutation |
| POLE | Breast Cancer | p137_p02 | p.1594_1596del | Private mutation |
| POLE | Breast Cancer | p137_p06 | p.A2262S | Private mutation |
| POLE | Breast Cancer | p137_p14 | p.L1473P | Trunk mutation |
| POLE | Breast Cancer | p143_p4 | Chr12:133241030:C>T | Branch mutation |
| POLE | Breast Cancer | p143_p5 | Chr12:133215787:G>A | Branch mutation |
| POLE | Colorectal Cancer | p005_CRC_P3 | p.G1924R | Trunk mutation |
| POLE | Colorectal Cancer | p034_MSU1 | Chr12:133214669:C>T | Trunk mutation |
| POLE | Colorectal Cancer | p034_MSU2 | Chr12:133250211:C>T | Trunk mutation |
| POLE | Colorectal Cancer | p034_MSU3 | Chr12:133252023-133252024:TC>T | Private mutation |
| POLE | Colorectal Cancer | p104_CD02 | p.R1691H | Branch mutation |
| POLE | Colorectal Cancer | p104_UC02 | p.R1471L | Branch mutation |
| POLE | Colorectal Cancer | p104_UC02 | p.A1349V | Branch mutation |
| POLE | Colorectal Cancer | p155_p494 | p.H422Y | Private mutation |
| POLE | Esophageal Squamous Cell Carcinoma | p008_ESCC13 | p.E1091K | Trunk mutation |
| POLE | Esophageal Squamous Cell Carcinoma | p124_ESCC026 | p.E74* | Branch mutation |
| POLE | Esophageal Squamous Cell Carcinoma | p124_ESCC038 | p.H379Q | Private mutation |
| POLE | Esophageal Squamous Cell Carcinoma | p128_P19 | Chr12:133202720:G>C | Private mutation |
| POLE | Esophageal Squamous Cell Carcinoma | p128_SP23 | Chr12:133218928:G>A | Private mutation |
| POLE | Esophageal Squamous Cell Carcinoma | p128_SP25 | Chr12:133254211:G>A | Private mutation |
| POLE | Esophageal Squamous Cell Carcinoma | p139_EC1111 | p.A1597G | Private mutation |
| POLE | Gastric Adenocarcinoma | p011_MSI-H2 | p.P441P | Trunk mutation |
| POLE | Gastric Adenocarcinoma | p011_MSI-H2 | p.L979L | Trunk mutation |
| POLE | Gastric Adenocarcinoma | p011_MSI-H2 | p.A1778A | Trunk mutation |
| POLE | Gastric Carcinoma | p106_GC03 | p.R685Q | Private mutation |
| POLE | Gastric Carcinoma | p106_GC04 | p.L424F | Private mutation |
| POLE | Gastric Carcinoma | p106_GC07 | p.N875Y | Private mutation |
| POLE | Gastric Carcinoma | p106_GC07 | p.E584D | Private mutation |
| POLE | Glioblastoma | p070_HGG2 | Chr12:133220018:C>A | Branch mutation |
| POLE | Glioblastoma | p079_GS01 | p.D287H | Private mutation |
| POLE | Glioblastoma | p113_case01 | p.D1405N | Private mutation |
| POLE | Glioblastoma | p113_case22 | p.V1446Gfs*3 | Private mutation |
| POLE | Glioma | p168_P01 | p.P282L | Branch mutation |
| POLE | Glioma | p168_P01 | p.E591E | Private mutation |
| POLE | Melanoma | p002_PMME | p.Q2143K | Branch mutation |
| POLE | Melanoma | p043_H | p.V210I | Private mutation |
| POLE | Prostate Cancer | p136_p177 | - | Branch mutation |
| POLE | Prostate Cancer | p136_p299 | - | Branch mutation |
| POLE | Prostate Cancer | p164_P1 | p.A992T | Branch mutation |
| POLE | Clear Cell Renal Cell Carcinoma | p025_CCCFP10 | - | Branch mutation |
| POLE | Renal Cell Carcinoma | p073_RCC6 | Chr12:133245329:A>G | Branch mutation |
| POLE | Urothelial Carcinoma | p031_WCM077 | p.G1923G | Private mutation |
| POLE | Urothelial Carcinoma | p031_WCM117 | p.R1160H | Private mutation |
| POLE | Urothelial Carcinoma | p142_p27 | - | Private mutation |