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Gene/Event	Cancer Type	Patient	Variant	Mutation Level
PRUNE2	Breast Cancer	p091_A7	p.A1707	Branch mutation
PRUNE2	Breast Cancer	p111_p10-80	p.E2133K	Branch mutation
PRUNE2	Breast Cancer	p131_case5	p.E1957_Q1960del	Trunk mutation
PRUNE2	Breast Cancer	p143_p1	Chr9:79324994:G>A	Private mutation
PRUNE2	Breast Cancer	p143_p5	Chr9:79321386:T>C	Private mutation
PRUNE2	Carcinosarcoma of the uterus and ovary	p009_SAR33	-	Trunk mutation
PRUNE2	Osteosarcoma	p112_OS010	E19_UTR_3	Private mutation
PRUNE2	Colorectal Cancer	p001_PCRC05	Chr9:79229392:G>A	Private mutation
PRUNE2	Colorectal Cancer	p034_MSS4	Chr9:79323994:A>C	Private mutation
PRUNE2	Colorectal Cancer	p147_a18	p.E3046G	Trunk mutation
PRUNE2	Colorectal Cancer	p147_a20	p.R2543C	Trunk mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p124_ESCC001	p.L493L	Trunk mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p124_ESCC006	p.A2067T	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p124_ESCC007	p.G1992D	Trunk mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p124_ESCC012	p.S827F	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p124_ESCC014	p.A670E	Trunk mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p124_ESCC015	p.S280P	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p124_ESCC024	p.E100E	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p128_P06	Chr9:79320602:C>T	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p128_P09	Chr9:79321057:C>A	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p128_P11	Chr9:79251428:G>C	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p128_P19	Chr9:79252341:G>A	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p128_P19	Chr9:79438617:G>C	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p128_SP06	Chr9:79320602:C>T	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p128_SP09	Chr9:79321057:C>A	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p128_SP24	Chr9:79321913:T>C	Private mutation
PRUNE2	Esophageal Squamous Cell Carcinoma	p139_EC1000	p.A2067T	Private mutation
PRUNE2	Gastric Adenocarcinoma	p011_MSI-H2	p.N817D	Trunk mutation
PRUNE2	Gastric Adenocarcinoma	p011_MSI-H2	p.T544T	Trunk mutation
PRUNE2	Gastric Adenocarcinoma	p011_MSI-H2	p.T1004M	Trunk mutation
PRUNE2	Gastric Adenocarcinoma	p011_MSI-H2	p.H1708N	Trunk mutation
PRUNE2	Gastric Adenocarcinoma	p011_MSI-H2	p.N2721S	Trunk mutation
PRUNE2	Gastric Adenocarcinoma	p011_MSI-H2	p.C2536C	Trunk mutation
PRUNE2	Gastric Carcinoma	p083_GAC	Chr9:79507838:A>-	Private mutation
PRUNE2	Gastric Carcinoma	p106_GC07	p.K1644T	Private mutation
PRUNE2	Gastric Carcinoma	p106_GC09	p.Q2204Q	Private mutation
PRUNE2	Glioblastoma	p070_HGG2	Chr9:79323861:T>A	Trunk mutation
PRUNE2	Glioblastoma	p113_case02	p.A1705V	Trunk mutation
PRUNE2	Glioblastoma	p113_case10	p.R1022*	Private mutation
PRUNE2	Glioblastoma	p113_case11	p.N817D	Private mutation
PRUNE2	Glioblastoma	p113_case14	p.G1308W	Private mutation
PRUNE2	Glioma	p168_P01	p.L113L	Private mutation
PRUNE2	Intrahepatic Cholangiocarcinoma	p080_ICC1370	Chr9:79324092:C>T	Private mutation
PRUNE2	Hepatocellular Carcinoma	p061_P06	Chr9:79318513:G>A	Trunk mutation
PRUNE2	Lung Adenocarcinoma	p017_330	Chr9:79465553:G>T	Private mutation
PRUNE2	Lung Adenocarcinoma	p083_X330	-	Private mutation
PRUNE2	Lung Adenocarcinoma	p134_A071	p.F710F	Trunk mutation
PRUNE2	Medulloblastoma	p072_MB3	Chr9:79318389:A>G	Branch mutation
PRUNE2	Melanoma	p043_A	p.P1619S	Trunk mutation
PRUNE2	Melanoma	p043_G	p.C308W	Trunk mutation
PRUNE2	Prostate Cancer	p164_P2	p.M745I	Private mutation
PRUNE2	Renal Cell Carcinoma	p073_RCC1	Chr9:79461497:C>T	Trunk mutation
PRUNE2	Renal Cell Carcinoma	p073_RCC3	Chr9:79244006:C>A	Private mutation
PRUNE2	Urothelial Carcinoma	p031_WCM088	p.Q1924*	Trunk mutation
PRUNE2	Urothelial Carcinoma	p031_WCM088	p.E1611K	Private mutation
PRUNE2	Urothelial Carcinoma	p031_WCM249	p.Q1573E	Branch mutation
PRUNE2	Urothelial Carcinoma	p142_p23	-	Trunk mutation

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