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Gene/Event	Cancer Type	Patient	Variant	Mutation Level
RYR1	Breast Cancer	p123_case1	p.R1301C	Trunk mutation
RYR1	Breast Cancer	p123_case8	p.E1906G	Branch mutation
RYR1	Breast Cancer	p143_p1	Chr19:38980107:C>T	Private mutation
RYR1	Breast Cancer	p143_p1	Chr19:38986973:A>T	Private mutation
RYR1	Breast Cancer	p143_p5	Chr19:39019152:G>C	Private mutation
RYR1	Breast Cancer	p143_p5	Chr19:39034142:A>C	Private mutation
RYR1	Breast Cancer	p143_p6	Chr19:38959592:G>C	Private mutation
RYR1	Colorectal Cancer	p001_PCRC08	Chr19:38993230:G>A	Private mutation
RYR1	Colorectal Cancer	p001_PCRC15	Chr19:38964367:G>A	Branch mutation
RYR1	Colorectal Cancer	p004_CRC_A03	Chr19:39027406:C>T	Trunk mutation
RYR1	Colorectal Cancer	p004_CRC_A04	Chr19:38990454:C>T	Trunk mutation
RYR1	Colorectal Cancer	p014_CRC2	p.G4896R	Trunk mutation
RYR1	Colorectal Cancer	p014_CRC3	p.R1469L	Branch mutation
RYR1	Colorectal Cancer	p014_CRC5	p.R425W	Trunk mutation
RYR1	Colorectal Cancer	p034_MSS4	Chr19:39018300:C>T	Private mutation
RYR1	Colorectal Cancer	p034_MSU1	Chr19:38976472:G>A	Trunk mutation
RYR1	Colorectal Cancer	p034_MSU1	Chr19:39051801:C>T	Trunk mutation
RYR1	Colorectal Cancer	p034_MSU1	Chr19:39034480:C>T	Private mutation
RYR1	Colorectal Cancer	p034_MSU4	Chr19:38948871:C>T	Trunk mutation
RYR1	Colorectal Cancer	p034_MSU4	Chr19:38932994:G>GC	Private mutation
RYR1	Colorectal Cancer	p034_MSU4	Chr19:39063876:C>T	Private mutation
RYR1	Colorectal Cancer	p155_p251	p.P3297P	Private mutation
RYR1	Colorectal Cancer	p155_p251	p.E2749E	Private mutation
RYR1	Colorectal Cancer	p155_p252	p.V1415A	Private mutation
RYR1	Colorectal Cancer	p155_p497	p.E1907K	Private mutation
RYR1	Colorectal Cancer	p156_p325	p.A4906T	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p008_ESCC01	p.T3177T	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p008_ESCC07	p.H1825H	Trunk mutation
RYR1	Esophageal Squamous Cell Carcinoma	p008_ESCC09	p.G627G	Trunk mutation
RYR1	Esophageal Squamous Cell Carcinoma	p008_ESCC09	p.N1346N	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC012	p.E4422K	Branch mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC012	p.E4449Q	Branch mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC012	p.E4740Q	Branch mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC012	p.E9K	Branch mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC012	p.F2425F	Branch mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC012	p.R3350Q	Branch mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC012	p.R4306P	Branch mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC012	p.S2685F	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC012	p.V1870V	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC015	p.E4390Q	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC025	p.F1222F	Branch mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC026	p.A3135T	Branch mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC029	p.L4012L	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC031	p.I1715I	Branch mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC031	p.D302N	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC035	p.E2078K	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC035	p.GLPRHLLTSLCP4505fs	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p124_ESCC043	p.E4464K	Trunk mutation
RYR1	Esophageal Squamous Cell Carcinoma	p128_P01	Chr19:39006845:C>T	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p128_P03	Chr19:39058416:C>T	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p128_P08	Chr19:38956839:C>T	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p128_P21	Chr19:38994881:C>T	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p128_SP07	Chr19:39051822:G>A	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p128_SP08	Chr19:38956839:C>T	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p139_EC0990	p.R3767fs	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p139_EC1117	p.A1826T	Private mutation
RYR1	Esophageal Squamous Cell Carcinoma	p139_EC1155	p.A3300fs	Branch mutation
RYR1	Gastric Adenocarcinoma	p011_MSS3	p.D2601D	Branch mutation
RYR1	Gastric Adenocarcinoma	p011_MSI-H1	p.R14W	Trunk mutation
RYR1	Gastric Adenocarcinoma	p011_MSI-H1	p.V4049M	Private mutation
RYR1	Gastric Adenocarcinoma	p011_MSI-H1	p.A4197T	Private mutation
RYR1	Gastric Carcinoma	p106_GC08	p.D2497N	Trunk mutation
RYR1	Gastric Carcinoma	p106_GC09	p.D4078G	Private mutation
RYR1	Gastric Carcinoma	p106_GC09	p.N3869N	Private mutation
RYR1	Glioma	p020_Patient04	p.D302D	Private mutation
RYR1	Glioblastoma	p113_case02	p.I2969V	Private mutation
RYR1	Glioblastoma	p113_case07	p.G760D	Private mutation
RYR1	Glioblastoma	p113_case07	p.A2492T	Private mutation
RYR1	Glioblastoma	p113_case08	p.G103D	Private mutation
RYR1	Glioblastoma	p113_case14	p.G2434R	Private mutation
RYR1	Glioblastoma	p113_case14	p.A3526V	Private mutation
RYR1	Glioblastoma	p113_case14	p.G4895D	Private mutation
RYR1	Glioblastoma	p113_case20	p.T1265M	Private mutation
RYR1	Glioblastoma	p113_case31	p.Q1219*	Private mutation
RYR1	Glioma	p168_P04	p.D302D	Private mutation
RYR1	Glioma	p168_P18	p.E2449K	Branch mutation
RYR1	Glioma	p168_P18	p.L1286F	Private mutation
RYR1	Glioma	p168_P90	p.V861F	Trunk mutation
RYR1	Hepato-Cholangiocarcinoma	p078_p2	p.T2822A	Trunk mutation
RYR1	Hepato-Cholangiocarcinoma	p078_p6	p.D3666Y	Private mutation
RYR1	Intrahepatic Cholangiocarcinoma	p080_ICC892	p.R1583L	Private mutation
RYR1	Hepatocellular Carcinoma	p151_HCC6046	Chr19:39009970:C>T	Private mutation
RYR1	Hepatocellular Carcinoma	p157_p5	p.A4288S	Private mutation
RYR1	Hepatocellular Carcinoma	p158_pa	Chr19:38958392:G>A	Branch mutation
RYR1	Lung Cancer	p028_RJLC2	p.T4289A	Trunk mutation
RYR1	Small Cell Lung Carcinoma	p100_p4	Chr19:38966016:C>A	Trunk mutation
RYR1	Non-Small Cell Lung Cancer	p107_P023	p.G963W	Branch mutation
RYR1	Lung Adenocarcinoma	p134_A006	p.F4213F	Private mutation
RYR1	Melanoma	p043_C	p.M402I	Trunk mutation
RYR1	Melanoma	p043_D	p.E4544K	Trunk mutation
RYR1	Melanoma	p043_H	p.D849N	Trunk mutation
RYR1	Ovarian Cancer	p052_Case1	p.Q3151R	Branch mutation
RYR1	Ovarian Cancer	p144_AOCS034	p.GTPQAGG1359GTPQAGG	Trunk mutation
RYR1	Ovarian Cancer	p144_AOCS094	p.R2403H	Private mutation
RYR1	Ovarian Cancer	p144_AOCS167	p.L1525F	Trunk mutation
RYR1	Ovarian Cancer	p144_AOCS167	p.F313Y	Private mutation
RYR1	Pancreatic Cancer	p054_Pa02	-	Trunk mutation
RYR1	Prostate Cancer	p023_patient05144	-	Private mutation
RYR1	Prostate Cancer	p105_1010	p.D3060D	Branch mutation
RYR1	Prostate Cancer	p105_1010	p.G2217G	Private mutation
RYR1	Prostate Cancer	p105_1029	p.S1174S	Trunk mutation
RYR1	Prostate Cancer	p118_CPCG0184	p.P3527T	Private mutation
RYR1	Prostate Cancer	p164_P2	p.V1551I	Private mutation
RYR1	Renal Cell Carcinoma	p073_RCC3	Chr19:38993187:G>A	Branch mutation
RYR1	Renal Cell Carcinoma	p073_RCC3	Chr19:38979879:C>A	Private mutation
RYR1	Renal Cell Carcinoma	p073_RCC3	Chr19:39052033:G>A	Private mutation
RYR1	Renal Cell Carcinoma	p073_RCC5	Chr19:38976459:G>C	Trunk mutation
RYR1	Renal Cell Carcinoma	p073_RCC5	Chr19:38959916:A>C	Branch mutation
RYR1	Renal Cell Carcinoma	p073_RCC5	Chr19:38968413:A>C	Branch mutation
RYR1	Urothelial Carcinoma	p031_WCM077	p.E2764K	Branch mutation
RYR1	Urothelial Carcinoma	p031_WCM077	p.R757C	Private mutation
RYR1	Urothelial Carcinoma	p031_WCM249	p.G4458R	Private mutation

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