ChromothripsisDB: a curated database of chromothripsis
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	Fusion Gene
	PubMed ID: 25079552	Case ID: TCGA-05-4422	Disease: Non Small-cell lung cancer	Genome Assembly: GRCh37/hg19
Gene Symbol 1 Chromosome1 Description 1 Gene Symbol 2 Chromosome2 Description 2 ALKBH4 7 alkB, alkylation repair homolog 4 (E. coli) LRWD1 7 leucine-rich repeats and WD repeat domain containing 1 ASAP1 8 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 HSP90AA1 14 heat shock protein 90kDa alpha (cytosolic), class A member 1 BACH2 6 BTB and CNC homology 1, basic leucine zipper transcription factor 2 STK3 8 serine/threonine kinase 3 C4orf46 4 chromosome 4 open reading frame 46 ETFDH 4 electron-transferring-flavoprotein dehydrogenase EIF2B1 12 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa GTF2H3 12 general transcription factor IIH, polypeptide 3, 34kDa EMID1 22 EMI domain containing 1 RHBDD3 22 rhomboid domain containing 3 F11R 1 F11 receptor USF1 1 upstream transcription factor 1 FLAD1 1 flavin adenine dinucleotide synthetase 1 LENEP 1 lens epithelial protein FRS3 6 fibroblast growth factor receptor substrate 3 PRICKLE4 6 prickle homolog 4 (Drosophila) GNGT1 7 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 CNTNAP2 7 contactin associated protein-like 2 GPR62 3 G protein-coupled receptor 62 PCBP4 3 poly(rC) binding protein 4 MEX3A 1 mex-3 RNA binding family member A LMNA 1 lamin A/C MFSD9 2 major facilitator superfamily domain containing 9 TMEM182 2 transmembrane protein 182 MMP16 8 matrix metallopeptidase 16 (membrane-inserted) ATAD2 8 ATPase family, AAA domain containing 2 MMRN2 10 multimerin 2 SNCG 10 synuclein, gamma (breast cancer-specific protein 1) OC90 8 otoconin 90 KHDRBS3 8 KH domain containing, RNA binding, signal transduction associated 3 OTUB1 11 OTU deubiquitinase, ubiquitin aldehyde binding 1 MACROD1 11 MACRO domain containing 1 PBRM1 3 polybromo 1 GNL3 3 guanine nucleotide binding protein-like 3 (nucleolar) PODXL2 3 podocalyxin-like 2 ABTB1 3 ankyrin repeat and BTB (POZ) domain containing 1 PPIL3 2 peptidylprolyl isomerase (cyclophilin)-like 3 NIF3L1 2 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) TNFRSF6B 20 tumor necrosis factor receptor superfamily, member 6b, decoy ARFRP1 20 ADP-ribosylation factor related protein 1 SAMD12 8 sterile alpha motif domain containing 12 OC90 8 otoconin 90 SLC2A4RG 20 SLC2A4 regulator ZBTB46 20 zinc finger and BTB domain containing 46 SLC6A20 3 solute carrier family 6 (proline IMINO transporter), member 20 MSL2 3 male-specific lethal 2 homolog (Drosophila) SLCO5A1 8 solute carrier organic anion transporter family, member 5A1 ATAD2 8 ATPase family, AAA domain containing 2 SMYD1 2 SET and MYND domain containing 1 ADARB2 10 adenosine deaminase, RNA-specific, B2 (non-functional) TBC1D1 4 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 UGCG 9 UDP-glucose ceramide glucosyltransferase TCP1 6 t-complex 1 MRPL18 6 mitochondrial ribosomal protein L18 TRPC1 3 transient receptor potential cation channel, subfamily C, member 1 NSMCE2 8 non-SMC element 2, MMS21 homolog (S. cerevisiae) ZBTB7B 1 zinc finger and BTB domain containing 7B DCST2 1 DC-STAMP domain containing 2

	Affected Gene
	PubMed ID: 25079552	Case ID: TCGA-05-4422	Disease: Non Small-cell lung cancer	Genome Assembly: GRCh37/hg19
Gene Symbol Entrez Gene Chromosome Start End Description ABTB1 80325 3 127391778 127399768 ankyrin repeat and BTB (POZ) domain containing 1 ADARB2 105 10 1228073 1779670 adenosine deaminase, RNA-specific, B2 (non-functional) ALKBH4 54784 7 102096685 102105323 alkB, alkylation repair homolog 4 (E. coli) ARFRP1 10139 20 62329996 62339377 ADP-ribosylation factor related protein 1 ASAP1 50807 8 131064353 131455906 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 ATAD2 29028 8 124332090 124428590 ATPase family, AAA domain containing 2 ATPAF2 91647 17 17880723 17942523 ATP synthase mitochondrial F1 complex assembly factor 2 BACH2 60468 6 90636248 91006627 BTB and CNC homology 1, basic leucine zipper transcription factor 2 BASP1 10409 5 17065707 17276943 brain abundant, membrane attached signal protein 1 C16orf86 388284 16 67700719 67702661 chromosome 16 open reading frame 86 C4orf46 201725 4 159587831 159593407 chromosome 4 open reading frame 46 C6orf136 221545 6 30614816 30620987 chromosome 6 open reading frame 136 CENPBD1 92806 16 90036206 90038942 CENPB DNA-binding domains containing 1 CNTNAP2 26047 7 145813453 148118090 contactin associated protein-like 2 DCST2 127579 1 154990996 155006257 DC-STAMP domain containing 2 EIF2B1 1967 12 124104953 124118313 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa EMID1 129080 22 29601840 29655586 EMI domain containing 1 ETFDH 2110 4 159593277 159630775 electron-transferring-flavoprotein dehydrogenase F11R 50848 1 160965001 160991138 F11 receptor FLAD1 80308 1 154955814 154965587 flavin adenine dinucleotide synthetase 1 FRS3 10817 6 41737914 41754280 fibroblast growth factor receptor substrate 3 GNGT1 2792 7 93220885 93540577 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 GNL3 26354 3 52715172 52728508 guanine nucleotide binding protein-like 3 (nucleolar) GPR62 118442 3 51989330 51991509 G protein-coupled receptor 62 GTF2H3 2967 12 124118375 124147153 general transcription factor IIH, polypeptide 3, 34kDa HSDL1 83693 16 84155886 84178797 hydroxysteroid dehydrogenase like 1 HSP90AA1 3320 14 102547075 102606036 heat shock protein 90kDa alpha (cytosolic), class A member 1 JMJD6 23210 17 74708919 74722866 jumonji domain containing 6 KHDRBS3 10656 8 136469700 136668965 KH domain containing, RNA binding, signal transduction associated 3 LENEP 55891 1 154966062 154966791 lens epithelial protein LMNA 4000 1 156052364 156109880 lamin A/C LRWD1 222229 7 102105376 102113615 leucine-rich repeats and WD repeat domain containing 1 MACROD1 28992 11 63766030 63933578 MACRO domain containing 1 METTL1 4234 12 58162254 58166576 methyltransferase like 1 MEX3A 92312 1 156041804 156051789 mex-3 RNA binding family member A MFSD9 84804 2 103332299 103353347 major facilitator superfamily domain containing 9 MMP16 4325 8 89044237 89340254 matrix metallopeptidase 16 (membrane-inserted) MMRN2 79812 10 88695297 88729238 multimerin 2 MRPL18 29074 6 160210844 160219468 mitochondrial ribosomal protein L18 MSL2 55167 3 135867764 135916083 male-specific lethal 2 homolog (Drosophila) NIF3L1 60491 2 201754050 201768655 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) NSMCE2 286053 8 126103921 126379362 non-SMC element 2, MMS21 homolog (S. cerevisiae) OC90 729330 8 133036467 133097902 otoconin 90 OTUB1 55611 11 63753325 63769283 OTU deubiquitinase, ubiquitin aldehyde binding 1 PBRM1 55193 3 52579368 52719933 polybromo 1 PCBP4 57060 3 51991470 52002426 poly(rC) binding protein 4 PODXL2 50512 3 127348024 127391652 podocalyxin-like 2 PPIL3 53938 2 201735630 201754026 peptidylprolyl isomerase (cyclophilin)-like 3 PRICKLE4 29964 6 41748087 41757879 prickle homolog 4 (Drosophila) PTPRE 5791 10 129705325 129884119 protein tyrosine phosphatase, receptor type, E RHBDD3 25807 22 29655841 29664198 rhomboid domain containing 3 RTEL1 51750 20 62289163 62328416 regulator of telomere elongation helicase 1 TNFRSF6B 8771 20 62328021 62330037 tumor necrosis factor receptor superfamily, member 6b, decoy SAMD12 401474 8 119201698 119634234 sterile alpha motif domain containing 12 SETD5 55209 3 9439299 9520924 SET domain containing 5 SLC2A4RG 56731 20 62371214 62374858 SLC2A4 regulator SLC6A20 54716 3 45796942 45838027 solute carrier family 6 (proline IMINO transporter), member 20 SLCO5A1 81796 8 70579282 70747299 solute carrier organic anion transporter family, member 5A1 SMYD1 150572 2 88367299 88412906 SET and MYND domain containing 1 SNCG 6623 10 88718375 88723017 synuclein, gamma (breast cancer-specific protein 1) SNRPD3 6634 22 24951471 25005947 small nuclear ribonucleoprotein D3 polypeptide 18kDa STK3 6788 8 99413631 99955055 serine/threonine kinase 3 TBC1D1 23216 4 37892708 38140796 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 TCP1 6950 6 160199530 160210781 t-complex 1 TMEM182 130827 2 103353367 103460352 transmembrane protein 182 TRPC1 7220 3 142442916 142526730 transient receptor potential cation channel, subfamily C, member 1 UGCG 7357 9 114659046 114697649 UDP-glucose ceramide glucosyltransferase USF1 7391 1 161009041 161015767 upstream transcription factor 1 ZBTB46 140685 20 62375019 62462597 zinc finger and BTB domain containing 46 ZBTB7B 51043 1 154975127 154990998 zinc finger and BTB domain containing 7B ZNF131 7690 5 43065278 43192123 zinc finger protein 131 ZNF589 51385 3 48282590 48340743 zinc finger protein 589 top

Chromothripsis database. 2025 Cai Laboratory