CYP51A1

 

Full name: cytochrome P450 family 51 subfamily A member 1 Alias Symbol: CP51|CYPL1|P450L1|LDM|P450-14DM
Type: protein-coding gene Cytoband: 7q21.2
Entrez ID: 1595 HGNC ID: HGNC:2649 Ensembl Gene: ENSG00000001630 OMIM ID: 601637
Drug and gene relationship at DGIdb

 

Expression of CYP51A1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 CYP51A1 1595 20561 -0.0152 0.8914
GSE53624 CYP51A1 1595 20561 -0.0841 0.3767
GSE97050 CYP51A1 1595 A_24_P130041 -0.1076 0.7560
SRP007169 CYP51A1 1595 RNAseq -0.6671 0.1170
SRP008496 CYP51A1 1595 RNAseq -0.6795 0.0217
SRP064894 CYP51A1 1595 RNAseq -0.5707 0.0047
SRP133303 CYP51A1 1595 RNAseq 0.5143 0.1029
SRP159526 CYP51A1 1595 RNAseq 0.1762 0.7194
SRP193095 CYP51A1 1595 RNAseq -0.0020 0.9931
SRP219564 CYP51A1 1595 RNAseq 0.0658 0.8691
TCGA CYP51A1 1595 RNAseq 0.0592 0.4251

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by CYP51A1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CYP51A1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CYP51A1 1595 13 0 17
GSE20123 CYP51A1 1595 13 0 17
GSE43470 CYP51A1 1595 6 1 36
GSE46452 CYP51A1 1595 11 0 48
GSE47630 CYP51A1 1595 9 2 29
GSE54993 CYP51A1 1595 1 8 61
GSE54994 CYP51A1 1595 16 2 35
GSE60625 CYP51A1 1595 0 0 11
GSE74703 CYP51A1 1595 5 1 30
GSE74704 CYP51A1 1595 9 0 11
TCGA CYP51A1 1595 56 4 36

Total number of gains: 139; Total number of losses: 18; Total Number of normals: 331.  

 

Somatic mutations of CYP51A1:

 

Generating mutation plots.

 

Highly correlated genes for CYP51A1:

 

Showing all 1 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CYP51A1SLC25A130.709907303

For details and further investigation, click here