MED18

 

Full name: mediator complex subunit 18 Alias Symbol: FLJ20045|p28b|SRB5
Type: protein-coding gene Cytoband: 1p35.3
Entrez ID: 54797 HGNC ID: HGNC:25944 Ensembl Gene: ENSG00000130772 OMIM ID: 612384
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of MED18:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 MED18 54797 91147 -0.5681 0.0000
GSE53624 MED18 54797 91147 -0.4892 0.0000
GSE97050 MED18 54797 A_23_P138105 -0.1672 0.5129
SRP007169 MED18 54797 RNAseq -1.4007 0.0003
SRP008496 MED18 54797 RNAseq -1.3454 0.0000
SRP064894 MED18 54797 RNAseq -0.4430 0.0293
SRP133303 MED18 54797 RNAseq -0.1861 0.0876
SRP159526 MED18 54797 RNAseq -0.6247 0.0268
SRP193095 MED18 54797 RNAseq -0.4900 0.0000
SRP219564 MED18 54797 RNAseq -0.9080 0.0420
TCGA MED18 54797 RNAseq -0.1164 0.0968

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by MED18 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MED18:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MED18 54797 0 6 24
GSE20123 MED18 54797 0 5 25
GSE43470 MED18 54797 3 6 34
GSE46452 MED18 54797 5 1 53
GSE47630 MED18 54797 8 3 29
GSE54993 MED18 54797 2 1 67
GSE54994 MED18 54797 10 4 39
GSE60625 MED18 54797 0 0 11
GSE74703 MED18 54797 2 4 30
GSE74704 MED18 54797 0 0 20
TCGA MED18 54797 11 23 62

Total number of gains: 41; Total number of losses: 53; Total Number of normals: 394.  

 

Somatic mutations of MED18:

 

Generating mutation plots.

 

Highly correlated genes for MED18:

 

Showing all 1 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MED18GOLGA20.718291303

For details and further investigation, click here