SIAH3

 

Full name: siah E3 ubiquitin protein ligase family member 3 Alias Symbol: FLJ39203
Type: protein-coding gene Cytoband: 13q14.13
Entrez ID: 283514 HGNC ID: HGNC:30553 Ensembl Gene: ENSG00000215475 OMIM ID: 615609
Drug and gene relationship at DGIdb

 

Expression of SIAH3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SIAH3 283514 1560676_at -0.0850 0.6657
GSE26886 SIAH3 283514 1560676_at 0.0310 0.7242
GSE45670 SIAH3 283514 1560676_at 0.0247 0.7369
GSE53622 SIAH3 283514 6571 -0.2735 0.2515
GSE53624 SIAH3 283514 6571 -0.5047 0.0004
GSE63941 SIAH3 283514 1560676_at 0.1851 0.1715
GSE77861 SIAH3 283514 1560676_at -0.0650 0.4572
SRP133303 SIAH3 283514 RNAseq -0.3693 0.1506
TCGA SIAH3 283514 RNAseq 1.0090 0.2394

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by SIAH3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SIAH3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SIAH3 283514 0 14 16
GSE20123 SIAH3 283514 0 13 17
GSE43470 SIAH3 283514 3 13 27
GSE46452 SIAH3 283514 0 33 26
GSE47630 SIAH3 283514 2 27 11
GSE54993 SIAH3 283514 12 2 56
GSE54994 SIAH3 283514 1 16 36
GSE60625 SIAH3 283514 0 3 8
GSE74703 SIAH3 283514 3 10 23
GSE74704 SIAH3 283514 0 10 10
TCGA SIAH3 283514 8 39 49

Total number of gains: 29; Total number of losses: 180; Total Number of normals: 279.  

 

Somatic mutations of SIAH3:

 

Generating mutation plots.

 

Highly correlated genes for SIAH3:

 

Showing all 1 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SIAH3CCER10.643968303

For details and further investigation, click here