CKMT1B

 

Full name: creatine kinase, mitochondrial 1B Alias Symbol: UMTCK
Type: protein-coding gene Cytoband: 15q15.3
Entrez ID: 1159 HGNC ID: HGNC:1995 Ensembl Gene: ENSG00000237289 OMIM ID: 123290
Drug and gene relationship at DGIdb

 

Expression of CKMT1B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 CKMT1B 1159 72653 -0.9828 0.0014
GSE53624 CKMT1B 1159 72653 -1.0136 0.0000
SRP007169 CKMT1B 1159 RNAseq -1.1738 0.0074
SRP008496 CKMT1B 1159 RNAseq -1.1900 0.0193
SRP064894 CKMT1B 1159 RNAseq -0.3500 0.4826
SRP133303 CKMT1B 1159 RNAseq -0.5059 0.4146
SRP159526 CKMT1B 1159 RNAseq -1.3636 0.0382
SRP193095 CKMT1B 1159 RNAseq -0.8517 0.0000
SRP219564 CKMT1B 1159 RNAseq -1.0175 0.3310
TCGA CKMT1B 1159 RNAseq 0.2487 0.1750

Upregulated datasets: 0; Downregulated datasets: 4.  

 

Survival by CKMT1B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CKMT1B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CKMT1B 1159 3 4 23
GSE20123 CKMT1B 1159 3 5 22
GSE43470 CKMT1B 1159 3 5 35
GSE46452 CKMT1B 1159 3 7 49
GSE47630 CKMT1B 1159 8 10 22
GSE54993 CKMT1B 1159 4 6 60
GSE54994 CKMT1B 1159 5 7 41
GSE60625 CKMT1B 1159 4 0 7
GSE74703 CKMT1B 1159 3 3 30
GSE74704 CKMT1B 1159 2 2 16
TCGA CKMT1B 1159 12 17 67

Total number of gains: 50; Total number of losses: 66; Total Number of normals: 372.  

 

Somatic mutations of CKMT1B:

 

Generating mutation plots.

 

Highly correlated genes for CKMT1B:

 

Showing all 1 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CKMT1BCKMT1A0.973058303

For details and further investigation, click here