| Full name: creatine kinase, mitochondrial 1A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q15.3 | ||
| Entrez ID: 548596 | HGNC ID: HGNC:31736 | Ensembl Gene: ENSG00000223572 | OMIM ID: 613415 |
| Drug and gene relationship at DGIdb | |||
Expression of CKMT1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | CKMT1A | 548596 | 429 | -1.0638 | 0.0002 | |
| GSE53624 | CKMT1A | 548596 | 429 | -1.0505 | 0.0000 | |
| GSE97050 | CKMT1A | 548596 | A_23_P163227 | 0.2748 | 0.7630 | |
| SRP007169 | CKMT1A | 548596 | RNAseq | -1.4356 | 0.0200 | |
| SRP008496 | CKMT1A | 548596 | RNAseq | -1.3365 | 0.0029 | |
| SRP064894 | CKMT1A | 548596 | RNAseq | -0.5353 | 0.2555 | |
| SRP133303 | CKMT1A | 548596 | RNAseq | -0.9767 | 0.1241 | |
| SRP159526 | CKMT1A | 548596 | RNAseq | -1.6801 | 0.0360 | |
| SRP193095 | CKMT1A | 548596 | RNAseq | -0.8892 | 0.0002 | |
| SRP219564 | CKMT1A | 548596 | RNAseq | -0.8533 | 0.5067 | |
| TCGA | CKMT1A | 548596 | RNAseq | 0.1791 | 0.4487 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by CKMT1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CKMT1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CKMT1A | 548596 | 3 | 4 | 23 | |
| GSE20123 | CKMT1A | 548596 | 3 | 5 | 22 | |
| GSE43470 | CKMT1A | 548596 | 3 | 5 | 35 | |
| GSE46452 | CKMT1A | 548596 | 3 | 7 | 49 | |
| GSE47630 | CKMT1A | 548596 | 8 | 10 | 22 | |
| GSE54993 | CKMT1A | 548596 | 4 | 6 | 60 | |
| GSE54994 | CKMT1A | 548596 | 5 | 7 | 41 | |
| GSE60625 | CKMT1A | 548596 | 4 | 0 | 7 | |
| GSE74703 | CKMT1A | 548596 | 3 | 3 | 30 | |
| GSE74704 | CKMT1A | 548596 | 2 | 2 | 16 | |
| TCGA | CKMT1A | 548596 | 12 | 17 | 67 |
Total number of gains: 50; Total number of losses: 66; Total Number of normals: 372.
Somatic mutations of CKMT1A:
Generating mutation plots.
Highly correlated genes for CKMT1A:
Showing top 20/205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CKMT1A | CKMT1B | 0.973058 | 3 | 0 | 3 |
| CKMT1A | JUP | 0.792115 | 3 | 0 | 3 |
| CKMT1A | OSTF1 | 0.789155 | 3 | 0 | 3 |
| CKMT1A | MPZL2 | 0.774132 | 3 | 0 | 3 |
| CKMT1A | CERS3 | 0.752274 | 3 | 0 | 3 |
| CKMT1A | DHCR24 | 0.747125 | 3 | 0 | 3 |
| CKMT1A | EPN3 | 0.747055 | 3 | 0 | 3 |
| CKMT1A | DSG3 | 0.746567 | 3 | 0 | 3 |
| CKMT1A | NIPAL1 | 0.745845 | 3 | 0 | 3 |
| CKMT1A | RAPGEFL1 | 0.745508 | 3 | 0 | 3 |
| CKMT1A | TWF1 | 0.745286 | 3 | 0 | 3 |
| CKMT1A | LPAR5 | 0.744254 | 3 | 0 | 3 |
| CKMT1A | FAM110C | 0.743782 | 3 | 0 | 3 |
| CKMT1A | DAPP1 | 0.738122 | 3 | 0 | 3 |
| CKMT1A | SLC9A3R1 | 0.737786 | 3 | 0 | 3 |
| CKMT1A | C19orf33 | 0.73639 | 3 | 0 | 3 |
| CKMT1A | PPP1R13L | 0.729466 | 3 | 0 | 3 |
| CKMT1A | TPD52L1 | 0.72555 | 3 | 0 | 3 |
| CKMT1A | MBD2 | 0.721897 | 3 | 0 | 3 |
| CKMT1A | DUOXA1 | 0.719049 | 3 | 0 | 3 |
For details and further investigation, click here
