DGCR6

 

Full name: DiGeorge syndrome critical region gene 6 Alias Symbol: 
Type: protein-coding gene Cytoband: 22q11.21
Entrez ID: 8214 HGNC ID: HGNC:2846 Ensembl Gene: ENSG00000183628 OMIM ID: 601279
Drug and gene relationship at DGIdb

 

Expression of DGCR6:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 DGCR6 8214 117266 0.0749 0.3159
GSE53624 DGCR6 8214 117266 0.0368 0.6545
TCGA DGCR6 8214 RNAseq 0.2719 0.0012

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by DGCR6 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DGCR6:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DGCR6 8214 4 7 19
GSE20123 DGCR6 8214 4 7 19
GSE43470 DGCR6 8214 5 7 31
GSE46452 DGCR6 8214 32 2 25
GSE47630 DGCR6 8214 8 5 27
GSE54993 DGCR6 8214 3 6 61
GSE54994 DGCR6 8214 12 7 34
GSE60625 DGCR6 8214 5 0 6
GSE74703 DGCR6 8214 5 5 26
GSE74704 DGCR6 8214 2 4 14
TCGA DGCR6 8214 27 17 52

Total number of gains: 107; Total number of losses: 67; Total Number of normals: 314.  

 

Somatic mutations of DGCR6:

 

Generating mutation plots.

 

Highly correlated genes for DGCR6:

 

Showing all 1 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DGCR6DGCR6L0.795158303

For details and further investigation, click here