| Full name: DiGeorge syndrome critical region gene 6 like | Alias Symbol: FLJ10666 | ||
| Type: protein-coding gene | Cytoband: 22q11.21 | ||
| Entrez ID: 85359 | HGNC ID: HGNC:18551 | Ensembl Gene: ENSG00000128185 | OMIM ID: 609459 |
| Drug and gene relationship at DGIdb | |||
Expression of DGCR6L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DGCR6L | 85359 | 214024_s_at | 0.0329 | 0.9039 | |
| GSE20347 | DGCR6L | 85359 | 214024_s_at | 0.0027 | 0.9781 | |
| GSE23400 | DGCR6L | 85359 | 214024_s_at | -0.0864 | 0.0151 | |
| GSE26886 | DGCR6L | 85359 | 214024_s_at | -0.0238 | 0.8651 | |
| GSE29001 | DGCR6L | 85359 | 214024_s_at | 0.1186 | 0.4481 | |
| GSE38129 | DGCR6L | 85359 | 214024_s_at | -0.0224 | 0.7595 | |
| GSE45670 | DGCR6L | 85359 | 214024_s_at | 0.0530 | 0.5896 | |
| GSE53622 | DGCR6L | 85359 | 89760 | 0.0798 | 0.2286 | |
| GSE53624 | DGCR6L | 85359 | 89760 | 0.0838 | 0.2102 | |
| GSE63941 | DGCR6L | 85359 | 214024_s_at | 0.0166 | 0.9216 | |
| GSE77861 | DGCR6L | 85359 | 214024_s_at | -0.1052 | 0.4700 | |
| GSE97050 | DGCR6L | 85359 | A_23_P143569 | 0.0781 | 0.8099 | |
| SRP007169 | DGCR6L | 85359 | RNAseq | -0.5910 | 0.1192 | |
| SRP008496 | DGCR6L | 85359 | RNAseq | -0.2141 | 0.3218 | |
| SRP064894 | DGCR6L | 85359 | RNAseq | 0.8648 | 0.0250 | |
| SRP133303 | DGCR6L | 85359 | RNAseq | 0.1325 | 0.4068 | |
| SRP159526 | DGCR6L | 85359 | RNAseq | 0.1285 | 0.5820 | |
| SRP193095 | DGCR6L | 85359 | RNAseq | -0.1465 | 0.3827 | |
| SRP219564 | DGCR6L | 85359 | RNAseq | 0.3966 | 0.3182 | |
| TCGA | DGCR6L | 85359 | RNAseq | 0.0470 | 0.4508 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DGCR6L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DGCR6L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DGCR6L | 85359 | 5 | 7 | 18 | |
| GSE20123 | DGCR6L | 85359 | 5 | 7 | 18 | |
| GSE43470 | DGCR6L | 85359 | 4 | 7 | 32 | |
| GSE46452 | DGCR6L | 85359 | 33 | 1 | 25 | |
| GSE47630 | DGCR6L | 85359 | 8 | 5 | 27 | |
| GSE54993 | DGCR6L | 85359 | 3 | 6 | 61 | |
| GSE54994 | DGCR6L | 85359 | 12 | 7 | 34 | |
| GSE60625 | DGCR6L | 85359 | 5 | 0 | 6 | |
| GSE74703 | DGCR6L | 85359 | 4 | 5 | 27 | |
| GSE74704 | DGCR6L | 85359 | 3 | 4 | 13 | |
| TCGA | DGCR6L | 85359 | 27 | 17 | 52 |
Total number of gains: 109; Total number of losses: 66; Total Number of normals: 313.
Somatic mutations of DGCR6L:
Generating mutation plots.
Highly correlated genes for DGCR6L:
Showing top 20/231 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DGCR6L | DGCR6 | 0.795158 | 3 | 0 | 3 |
| DGCR6L | NAT8B | 0.789584 | 4 | 0 | 4 |
| DGCR6L | LCT | 0.73403 | 3 | 0 | 3 |
| DGCR6L | PCP2 | 0.7145 | 3 | 0 | 3 |
| DGCR6L | ZP2 | 0.693552 | 4 | 0 | 3 |
| DGCR6L | IQSEC3 | 0.688651 | 4 | 0 | 3 |
| DGCR6L | ABCC6 | 0.687502 | 4 | 0 | 4 |
| DGCR6L | KCNT1 | 0.680841 | 3 | 0 | 3 |
| DGCR6L | CDHR5 | 0.671136 | 4 | 0 | 3 |
| DGCR6L | PEX11G | 0.670021 | 3 | 0 | 3 |
| DGCR6L | GUCY2C | 0.664033 | 3 | 0 | 3 |
| DGCR6L | SHANK1 | 0.661258 | 5 | 0 | 5 |
| DGCR6L | PGLYRP1 | 0.656231 | 5 | 0 | 4 |
| DGCR6L | ADORA1 | 0.653154 | 5 | 0 | 5 |
| DGCR6L | GNMT | 0.653093 | 4 | 0 | 3 |
| DGCR6L | HUNK | 0.649586 | 4 | 0 | 3 |
| DGCR6L | OR10C1 | 0.647561 | 4 | 0 | 3 |
| DGCR6L | CCL24 | 0.645881 | 4 | 0 | 3 |
| DGCR6L | LINC00302 | 0.645162 | 5 | 0 | 4 |
| DGCR6L | TNXB | 0.643214 | 5 | 0 | 4 |
For details and further investigation, click here
