RPL28

 

Full name: ribosomal protein L28 Alias Symbol: FLJ43307|L28
Type: protein-coding gene Cytoband: 19q13.4
Entrez ID: 6158 HGNC ID: HGNC:10330 Ensembl Gene: ENSG00000108107 OMIM ID: 603638
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of RPL28:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 RPL28 6158 113983 0.0965 0.2505
GSE53624 RPL28 6158 113983 0.3461 0.0000
GSE97050 RPL28 6158 A_23_P208358 0.5470 0.2319
SRP007169 RPL28 6158 RNAseq -1.2961 0.0012
SRP008496 RPL28 6158 RNAseq -1.2333 0.0000
SRP064894 RPL28 6158 RNAseq -0.0992 0.7921
SRP133303 RPL28 6158 RNAseq -0.3042 0.1177
SRP159526 RPL28 6158 RNAseq -0.6720 0.0062
SRP193095 RPL28 6158 RNAseq -0.8682 0.0001
SRP219564 RPL28 6158 RNAseq -0.0990 0.7425
TCGA RPL28 6158 RNAseq 0.1158 0.0211

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by RPL28 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RPL28:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RPL28 6158 3 4 23
GSE20123 RPL28 6158 3 3 24
GSE43470 RPL28 6158 3 11 29
GSE46452 RPL28 6158 45 1 13
GSE47630 RPL28 6158 8 6 26
GSE54993 RPL28 6158 17 4 49
GSE54994 RPL28 6158 4 13 36
GSE60625 RPL28 6158 9 0 2
GSE74703 RPL28 6158 3 7 26
GSE74704 RPL28 6158 3 1 16
TCGA RPL28 6158 20 14 62

Total number of gains: 118; Total number of losses: 64; Total Number of normals: 306.  

 

Somatic mutations of RPL28:

 

Generating mutation plots.

 

Highly correlated genes for RPL28:

 

Showing all 2 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RPL28RPS150.67328303
RPL28SNRPD20.598037303

For details and further investigation, click here