| Full name: small nuclear ribonucleoprotein D2 polypeptide | Alias Symbol: Sm-D2 | ||
| Type: protein-coding gene | Cytoband: 19q13.2-q13.3 | ||
| Entrez ID: 6633 | HGNC ID: HGNC:11159 | Ensembl Gene: ENSG00000125743 | OMIM ID: 601061 |
| Drug and gene relationship at DGIdb | |||
Expression of SNRPD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNRPD2 | 6633 | 200826_at | 0.3853 | 0.2518 | |
| GSE20347 | SNRPD2 | 6633 | 200826_at | 0.3026 | 0.0494 | |
| GSE23400 | SNRPD2 | 6633 | 200826_at | 0.5592 | 0.0000 | |
| GSE26886 | SNRPD2 | 6633 | 200826_at | 1.5818 | 0.0000 | |
| GSE29001 | SNRPD2 | 6633 | 200826_at | 0.2319 | 0.5473 | |
| GSE38129 | SNRPD2 | 6633 | 200826_at | 0.4315 | 0.0002 | |
| GSE45670 | SNRPD2 | 6633 | 200826_at | 0.1921 | 0.1325 | |
| GSE53622 | SNRPD2 | 6633 | 113521 | 0.3603 | 0.0000 | |
| GSE53624 | SNRPD2 | 6633 | 113521 | 0.7190 | 0.0000 | |
| GSE63941 | SNRPD2 | 6633 | 200826_at | 0.6399 | 0.0213 | |
| GSE77861 | SNRPD2 | 6633 | 200826_at | 0.1628 | 0.5148 | |
| GSE97050 | SNRPD2 | 6633 | A_24_P74160 | 0.2471 | 0.3077 | |
| SRP007169 | SNRPD2 | 6633 | RNAseq | 0.0293 | 0.9253 | |
| SRP008496 | SNRPD2 | 6633 | RNAseq | -0.0683 | 0.6796 | |
| SRP064894 | SNRPD2 | 6633 | RNAseq | 0.7847 | 0.0463 | |
| SRP133303 | SNRPD2 | 6633 | RNAseq | 0.4320 | 0.0261 | |
| SRP159526 | SNRPD2 | 6633 | RNAseq | 0.5075 | 0.0065 | |
| SRP193095 | SNRPD2 | 6633 | RNAseq | -0.0349 | 0.8172 | |
| SRP219564 | SNRPD2 | 6633 | RNAseq | 0.1094 | 0.6701 | |
| TCGA | SNRPD2 | 6633 | RNAseq | 0.2702 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SNRPD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNRPD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNRPD2 | 6633 | 4 | 5 | 21 | |
| GSE20123 | SNRPD2 | 6633 | 4 | 4 | 22 | |
| GSE43470 | SNRPD2 | 6633 | 3 | 11 | 29 | |
| GSE46452 | SNRPD2 | 6633 | 45 | 1 | 13 | |
| GSE47630 | SNRPD2 | 6633 | 8 | 7 | 25 | |
| GSE54993 | SNRPD2 | 6633 | 17 | 4 | 49 | |
| GSE54994 | SNRPD2 | 6633 | 5 | 13 | 35 | |
| GSE60625 | SNRPD2 | 6633 | 9 | 0 | 2 | |
| GSE74703 | SNRPD2 | 6633 | 3 | 7 | 26 | |
| GSE74704 | SNRPD2 | 6633 | 4 | 2 | 14 | |
| TCGA | SNRPD2 | 6633 | 16 | 15 | 65 |
Total number of gains: 118; Total number of losses: 69; Total Number of normals: 301.
Somatic mutations of SNRPD2:
Generating mutation plots.
Highly correlated genes for SNRPD2:
Showing top 20/1592 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNRPD2 | ZCCHC7 | 0.785329 | 3 | 0 | 3 |
| SNRPD2 | ETV6 | 0.781044 | 3 | 0 | 3 |
| SNRPD2 | PACS1 | 0.766356 | 3 | 0 | 3 |
| SNRPD2 | SSBP4 | 0.763918 | 4 | 0 | 3 |
| SNRPD2 | ZAP70 | 0.758356 | 3 | 0 | 3 |
| SNRPD2 | SMARCAD1 | 0.747378 | 3 | 0 | 3 |
| SNRPD2 | GPR160 | 0.742995 | 3 | 0 | 3 |
| SNRPD2 | ANKRD54 | 0.742945 | 3 | 0 | 3 |
| SNRPD2 | LRRC58 | 0.740873 | 3 | 0 | 3 |
| SNRPD2 | EBNA1BP2 | 0.73894 | 3 | 0 | 3 |
| SNRPD2 | MTHFD1L | 0.736688 | 3 | 0 | 3 |
| SNRPD2 | ARHGAP18 | 0.729901 | 3 | 0 | 3 |
| SNRPD2 | HES4 | 0.72982 | 3 | 0 | 3 |
| SNRPD2 | SPATA2 | 0.7264 | 3 | 0 | 3 |
| SNRPD2 | NAF1 | 0.726171 | 3 | 0 | 3 |
| SNRPD2 | LMO1 | 0.723075 | 3 | 0 | 3 |
| SNRPD2 | FNDC3A | 0.72179 | 3 | 0 | 3 |
| SNRPD2 | PIK3R3 | 0.711829 | 4 | 0 | 3 |
| SNRPD2 | NR1H3 | 0.709249 | 4 | 0 | 3 |
| SNRPD2 | UCK2 | 0.708955 | 3 | 0 | 3 |
For details and further investigation, click here
