SPATC1

 

Full name: spermatogenesis and centriole associated 1 Alias Symbol: MGC61633|SPATA15|SPERIOLIN
Type: protein-coding gene Cytoband: 8q24.3
Entrez ID: 375686 HGNC ID: HGNC:30510 Ensembl Gene: ENSG00000186583 OMIM ID: 610874
Drug and gene relationship at DGIdb

 

Expression of SPATC1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SPATC1 375686 241512_at 0.0426 0.8816
GSE26886 SPATC1 375686 241512_at -0.0654 0.6393
GSE45670 SPATC1 375686 241512_at 0.0575 0.5002
GSE53622 SPATC1 375686 8044 0.2330 0.0390
GSE53624 SPATC1 375686 8044 0.4783 0.0000
GSE63941 SPATC1 375686 241512_at -0.0125 0.9411
GSE77861 SPATC1 375686 241512_at -0.1560 0.1312
SRP133303 SPATC1 375686 RNAseq 0.7100 0.0525
TCGA SPATC1 375686 RNAseq 1.0534 0.0059

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by SPATC1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SPATC1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SPATC1 375686 17 1 12
GSE20123 SPATC1 375686 17 1 12
GSE43470 SPATC1 375686 16 2 25
GSE46452 SPATC1 375686 27 0 32
GSE47630 SPATC1 375686 23 1 16
GSE54993 SPATC1 375686 0 25 45
GSE54994 SPATC1 375686 39 1 13
GSE60625 SPATC1 375686 3 4 4
GSE74703 SPATC1 375686 14 1 21
GSE74704 SPATC1 375686 10 0 10
TCGA SPATC1 375686 63 2 31

Total number of gains: 229; Total number of losses: 38; Total Number of normals: 221.  

 

Somatic mutations of SPATC1:

 

Generating mutation plots.

 

Highly correlated genes for SPATC1:

 

Showing all 3 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SPATC1SPATC1L0.63134403
SPATC1PAGE50.575551403
SPATC1LINC013420.573738303

For details and further investigation, click here