| Full name: spermatogenesis and centriole associated 1 like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 84221 | HGNC ID: HGNC:1298 | Ensembl Gene: ENSG00000160284 | OMIM ID: 612412 |
| Drug and gene relationship at DGIdb | |||
Expression of SPATC1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPATC1L | 84221 | 223360_at | 1.0175 | 0.0310 | |
| GSE26886 | SPATC1L | 84221 | 223360_at | 0.8065 | 0.0001 | |
| GSE45670 | SPATC1L | 84221 | 223360_at | 0.2674 | 0.1233 | |
| GSE53622 | SPATC1L | 84221 | 34987 | 0.1867 | 0.0797 | |
| GSE53624 | SPATC1L | 84221 | 34987 | 0.3768 | 0.0000 | |
| GSE63941 | SPATC1L | 84221 | 223360_at | 1.6833 | 0.0235 | |
| GSE77861 | SPATC1L | 84221 | 223360_at | -0.1002 | 0.7339 | |
| SRP007169 | SPATC1L | 84221 | RNAseq | 1.0774 | 0.1094 | |
| SRP008496 | SPATC1L | 84221 | RNAseq | 0.4810 | 0.2531 | |
| SRP064894 | SPATC1L | 84221 | RNAseq | 1.3038 | 0.0030 | |
| SRP133303 | SPATC1L | 84221 | RNAseq | 0.1180 | 0.6763 | |
| SRP159526 | SPATC1L | 84221 | RNAseq | 0.8026 | 0.0035 | |
| SRP193095 | SPATC1L | 84221 | RNAseq | 0.3404 | 0.0743 | |
| SRP219564 | SPATC1L | 84221 | RNAseq | 0.6901 | 0.2639 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SPATC1L expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SPATC1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPATC1L | 84221 | 3 | 9 | 18 | |
| GSE20123 | SPATC1L | 84221 | 3 | 9 | 18 | |
| GSE43470 | SPATC1L | 84221 | 0 | 14 | 29 | |
| GSE46452 | SPATC1L | 84221 | 1 | 21 | 37 | |
| GSE47630 | SPATC1L | 84221 | 6 | 17 | 17 | |
| GSE54993 | SPATC1L | 84221 | 8 | 1 | 61 | |
| GSE54994 | SPATC1L | 84221 | 5 | 8 | 40 | |
| GSE60625 | SPATC1L | 84221 | 0 | 0 | 11 | |
| GSE74703 | SPATC1L | 84221 | 0 | 10 | 26 | |
| GSE74704 | SPATC1L | 84221 | 1 | 5 | 14 | |
| TCGA | SPATC1L | 84221 | 10 | 38 | 48 |
Total number of gains: 37; Total number of losses: 132; Total Number of normals: 319.
Somatic mutations of SPATC1L:
Generating mutation plots.
Highly correlated genes for SPATC1L:
Showing top 20/209 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPATC1L | FAM161A | 0.777665 | 3 | 0 | 3 |
| SPATC1L | GNGT1 | 0.721111 | 3 | 0 | 3 |
| SPATC1L | STK3 | 0.713914 | 3 | 0 | 3 |
| SPATC1L | PGM2L1 | 0.710506 | 3 | 0 | 3 |
| SPATC1L | HSP90AB1 | 0.699948 | 3 | 0 | 3 |
| SPATC1L | PFDN4 | 0.694405 | 3 | 0 | 3 |
| SPATC1L | RBM38 | 0.685412 | 3 | 0 | 3 |
| SPATC1L | CD320 | 0.678409 | 4 | 0 | 4 |
| SPATC1L | B3GALT6 | 0.677289 | 3 | 0 | 3 |
| SPATC1L | COLGALT1 | 0.674747 | 3 | 0 | 3 |
| SPATC1L | CNPY3 | 0.657899 | 3 | 0 | 3 |
| SPATC1L | CMSS1 | 0.657158 | 4 | 0 | 4 |
| SPATC1L | TUBB | 0.655332 | 3 | 0 | 3 |
| SPATC1L | CAMSAP2 | 0.653377 | 3 | 0 | 3 |
| SPATC1L | LRFN1 | 0.651398 | 3 | 0 | 3 |
| SPATC1L | PTDSS1 | 0.65089 | 3 | 0 | 3 |
| SPATC1L | MFAP2 | 0.649995 | 4 | 0 | 3 |
| SPATC1L | PLXNA1 | 0.649123 | 3 | 0 | 3 |
| SPATC1L | MEX3D | 0.646142 | 3 | 0 | 3 |
| SPATC1L | UBE2S | 0.644074 | 4 | 0 | 4 |
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