WFDC10B

 

Full name: WAP four-disulfide core domain 10B Alias Symbol: WAP12
Type: protein-coding gene Cytoband: 20q13.12
Entrez ID: 280664 HGNC ID: HGNC:20479 Ensembl Gene: ENSG00000182931 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of WFDC10B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 WFDC10B 280664 1552999_a_at 0.2183 0.3100
GSE26886 WFDC10B 280664 1552999_a_at -0.1446 0.2124
GSE45670 WFDC10B 280664 1552999_a_at -0.0225 0.8361
GSE53622 WFDC10B 280664 81317 0.1643 0.3151
GSE53624 WFDC10B 280664 81317 0.3046 0.0461
GSE63941 WFDC10B 280664 1552999_a_at 0.1010 0.4889
GSE77861 WFDC10B 280664 1552999_a_at -0.2067 0.0355
TCGA WFDC10B 280664 RNAseq 0.5914 0.5430

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by WFDC10B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of WFDC10B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 WFDC10B 280664 14 1 15
GSE20123 WFDC10B 280664 14 1 15
GSE43470 WFDC10B 280664 12 1 30
GSE46452 WFDC10B 280664 29 0 30
GSE47630 WFDC10B 280664 24 1 15
GSE54993 WFDC10B 280664 0 17 53
GSE54994 WFDC10B 280664 25 0 28
GSE60625 WFDC10B 280664 0 0 11
GSE74703 WFDC10B 280664 10 1 25
GSE74704 WFDC10B 280664 10 0 10
TCGA WFDC10B 280664 45 3 48

Total number of gains: 183; Total number of losses: 25; Total Number of normals: 280.  

 

Somatic mutations of WFDC10B:

 

Generating mutation plots.

 

Highly correlated genes for WFDC10B:

 

Showing all 2 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
WFDC10BTSGA130.5184303
WFDC10BHSF50.512045403

For details and further investigation, click here