| Full name: heat shock transcription factor 5 | Alias Symbol: FLJ40311 | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 124535 | HGNC ID: HGNC:26862 | Ensembl Gene: ENSG00000176160 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HSF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSF5 | 124535 | 230718_at | 0.1222 | 0.6398 | |
| GSE26886 | HSF5 | 124535 | 230718_at | -0.0026 | 0.9862 | |
| GSE45670 | HSF5 | 124535 | 230718_at | -0.0481 | 0.6482 | |
| GSE53622 | HSF5 | 124535 | 48642 | -0.1768 | 0.1151 | |
| GSE53624 | HSF5 | 124535 | 48642 | -0.5399 | 0.0002 | |
| GSE63941 | HSF5 | 124535 | 230718_at | -0.3045 | 0.0029 | |
| GSE77861 | HSF5 | 124535 | 230718_at | -0.1438 | 0.0857 | |
| TCGA | HSF5 | 124535 | RNAseq | -0.4878 | 0.5010 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HSF5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSF5 | 124535 | 5 | 1 | 24 | |
| GSE20123 | HSF5 | 124535 | 5 | 1 | 24 | |
| GSE43470 | HSF5 | 124535 | 3 | 0 | 40 | |
| GSE46452 | HSF5 | 124535 | 32 | 0 | 27 | |
| GSE47630 | HSF5 | 124535 | 7 | 1 | 32 | |
| GSE54993 | HSF5 | 124535 | 2 | 5 | 63 | |
| GSE54994 | HSF5 | 124535 | 8 | 6 | 39 | |
| GSE60625 | HSF5 | 124535 | 4 | 0 | 7 | |
| GSE74703 | HSF5 | 124535 | 3 | 0 | 33 | |
| GSE74704 | HSF5 | 124535 | 4 | 1 | 15 | |
| TCGA | HSF5 | 124535 | 27 | 8 | 61 |
Total number of gains: 100; Total number of losses: 23; Total Number of normals: 365.
Somatic mutations of HSF5:
Generating mutation plots.
Highly correlated genes for HSF5:
Showing all 14 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSF5 | DPF3 | 0.703625 | 3 | 0 | 3 |
| HSF5 | COL14A1 | 0.656151 | 3 | 0 | 3 |
| HSF5 | FCRL3 | 0.655103 | 3 | 0 | 3 |
| HSF5 | VN1R4 | 0.594205 | 3 | 0 | 3 |
| HSF5 | FCRLA | 0.585524 | 5 | 0 | 3 |
| HSF5 | GNGT2 | 0.574019 | 3 | 0 | 3 |
| HSF5 | PID1 | 0.571112 | 3 | 0 | 3 |
| HSF5 | TBC1D10C | 0.566057 | 3 | 0 | 3 |
| HSF5 | FGF10 | 0.560961 | 3 | 0 | 3 |
| HSF5 | NAAA | 0.559519 | 3 | 0 | 3 |
| HSF5 | SCGN | 0.552137 | 3 | 0 | 3 |
| HSF5 | ZNF582 | 0.529549 | 3 | 0 | 3 |
| HSF5 | ARHGAP6 | 0.517711 | 4 | 0 | 3 |
| HSF5 | WFDC10B | 0.512045 | 4 | 0 | 3 |
For details and further investigation, click here
