CRYGS

 

Full name: crystallin gamma S Alias Symbol: 
Type: protein-coding gene Cytoband: 3q27.3
Entrez ID: 1427 HGNC ID: HGNC:2417 Ensembl Gene: ENSG00000213139 OMIM ID: 123730
Drug and gene relationship at DGIdb

 

Expression of CRYGS:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CRYGS 1427 223644_s_at -0.3170 0.7606
GSE26886 CRYGS 1427 223644_s_at -0.1295 0.5562
GSE45670 CRYGS 1427 223644_s_at 0.1357 0.6425
GSE53622 CRYGS 1427 76269 -0.3501 0.0302
GSE53624 CRYGS 1427 76269 -0.8716 0.0000
GSE63941 CRYGS 1427 223644_s_at -0.3776 0.2101
GSE77861 CRYGS 1427 223644_s_at 0.0481 0.8674
GSE97050 CRYGS 1427 A_23_P132738 -0.0363 0.9088
SRP064894 CRYGS 1427 RNAseq 0.5524 0.0292
SRP133303 CRYGS 1427 RNAseq -0.1160 0.6671
SRP193095 CRYGS 1427 RNAseq -0.3131 0.1218
SRP219564 CRYGS 1427 RNAseq 0.3521 0.4882
TCGA CRYGS 1427 RNAseq -0.4744 0.0316

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by CRYGS expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CRYGS:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CRYGS 1427 24 0 6
GSE20123 CRYGS 1427 24 0 6
GSE43470 CRYGS 1427 23 0 20
GSE46452 CRYGS 1427 19 1 39
GSE47630 CRYGS 1427 27 2 11
GSE54993 CRYGS 1427 1 19 50
GSE54994 CRYGS 1427 40 0 13
GSE60625 CRYGS 1427 0 6 5
GSE74703 CRYGS 1427 20 0 16
GSE74704 CRYGS 1427 16 0 4
TCGA CRYGS 1427 77 0 19

Total number of gains: 271; Total number of losses: 28; Total Number of normals: 189.  

 

Somatic mutations of CRYGS:

 

Generating mutation plots.

 

Highly correlated genes for CRYGS:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CRYGSFANK10.624859303
CRYGSSHROOM40.606132303
CRYGSCSAD0.574595303
CRYGSPAQR60.503918403

For details and further investigation, click here