| Full name: cysteine sulfinic acid decarboxylase | Alias Symbol: PCAP|CSD | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 51380 | HGNC ID: HGNC:18966 | Ensembl Gene: ENSG00000139631 | OMIM ID: 616569 |
| Drug and gene relationship at DGIdb | |||
Expression of CSAD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CSAD | 51380 | 221139_s_at | -0.4113 | 0.5485 | |
| GSE20347 | CSAD | 51380 | 221139_s_at | -0.3188 | 0.1429 | |
| GSE23400 | CSAD | 51380 | 221139_s_at | -0.1783 | 0.0286 | |
| GSE26886 | CSAD | 51380 | 221139_s_at | -0.2903 | 0.4082 | |
| GSE29001 | CSAD | 51380 | 221139_s_at | -0.1205 | 0.7602 | |
| GSE38129 | CSAD | 51380 | 221139_s_at | -0.2718 | 0.0863 | |
| GSE45670 | CSAD | 51380 | 221139_s_at | -0.0461 | 0.8734 | |
| GSE53622 | CSAD | 51380 | 43399 | -0.0059 | 0.9544 | |
| GSE53624 | CSAD | 51380 | 43399 | 0.0428 | 0.6028 | |
| GSE63941 | CSAD | 51380 | 221139_s_at | -0.5765 | 0.3344 | |
| GSE77861 | CSAD | 51380 | 238764_at | -0.0918 | 0.3260 | |
| GSE97050 | CSAD | 51380 | A_24_P27229 | -0.4290 | 0.2422 | |
| SRP007169 | CSAD | 51380 | RNAseq | -0.2481 | 0.6792 | |
| SRP064894 | CSAD | 51380 | RNAseq | -0.2257 | 0.2894 | |
| SRP133303 | CSAD | 51380 | RNAseq | -0.1752 | 0.2048 | |
| SRP193095 | CSAD | 51380 | RNAseq | 0.2582 | 0.1976 | |
| SRP219564 | CSAD | 51380 | RNAseq | -0.1849 | 0.5826 | |
| TCGA | CSAD | 51380 | RNAseq | -0.1773 | 0.0418 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CSAD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CSAD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CSAD | 51380 | 8 | 1 | 21 | |
| GSE20123 | CSAD | 51380 | 8 | 1 | 21 | |
| GSE43470 | CSAD | 51380 | 3 | 0 | 40 | |
| GSE46452 | CSAD | 51380 | 7 | 1 | 51 | |
| GSE47630 | CSAD | 51380 | 10 | 2 | 28 | |
| GSE54993 | CSAD | 51380 | 0 | 5 | 65 | |
| GSE54994 | CSAD | 51380 | 4 | 1 | 48 | |
| GSE60625 | CSAD | 51380 | 0 | 0 | 11 | |
| GSE74703 | CSAD | 51380 | 3 | 0 | 33 | |
| GSE74704 | CSAD | 51380 | 5 | 1 | 14 | |
| TCGA | CSAD | 51380 | 13 | 11 | 72 |
Total number of gains: 61; Total number of losses: 23; Total Number of normals: 404.
Somatic mutations of CSAD:
Generating mutation plots.
Highly correlated genes for CSAD:
Showing top 20/55 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CSAD | MYH13 | 0.624513 | 3 | 0 | 3 |
| CSAD | SLC35C1 | 0.623699 | 3 | 0 | 3 |
| CSAD | PDZD2 | 0.611882 | 5 | 0 | 3 |
| CSAD | VWDE | 0.609057 | 3 | 0 | 3 |
| CSAD | PAF1 | 0.607088 | 5 | 0 | 3 |
| CSAD | SYBU | 0.604563 | 4 | 0 | 3 |
| CSAD | ROM1 | 0.604466 | 4 | 0 | 3 |
| CSAD | PRRT2 | 0.599171 | 4 | 0 | 3 |
| CSAD | NOXA1 | 0.594229 | 4 | 0 | 3 |
| CSAD | ARHGEF1 | 0.593718 | 5 | 0 | 4 |
| CSAD | POLM | 0.589514 | 5 | 0 | 4 |
| CSAD | TBKBP1 | 0.588169 | 6 | 0 | 3 |
| CSAD | PKD1 | 0.587931 | 4 | 0 | 3 |
| CSAD | KIFC2 | 0.586422 | 4 | 0 | 3 |
| CSAD | KCNQ4 | 0.58458 | 5 | 0 | 3 |
| CSAD | SLC48A1 | 0.581342 | 4 | 0 | 3 |
| CSAD | FANK1 | 0.578908 | 4 | 0 | 3 |
| CSAD | TRPS1 | 0.57886 | 5 | 0 | 3 |
| CSAD | AGER | 0.57885 | 4 | 0 | 3 |
| CSAD | SLC22A3 | 0.576181 | 4 | 0 | 3 |
For details and further investigation, click here
