| Full name: fibronectin type III and ankyrin repeat domains 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q26.2 | ||
| Entrez ID: 92565 | HGNC ID: HGNC:23527 | Ensembl Gene: ENSG00000203780 | OMIM ID: 611640 |
| Drug and gene relationship at DGIdb | |||
Expression of FANK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FANK1 | 92565 | 232968_at | -0.1140 | 0.8865 | |
| GSE26886 | FANK1 | 92565 | 232968_at | -0.8770 | 0.0307 | |
| GSE45670 | FANK1 | 92565 | 232968_at | -0.0204 | 0.9518 | |
| GSE53622 | FANK1 | 92565 | 38749 | -0.3195 | 0.0066 | |
| GSE53624 | FANK1 | 92565 | 38749 | -0.5138 | 0.0000 | |
| GSE63941 | FANK1 | 92565 | 232968_at | -2.0505 | 0.0003 | |
| GSE77861 | FANK1 | 92565 | 232968_at | -0.1433 | 0.4055 | |
| GSE97050 | FANK1 | 92565 | A_33_P3332492 | 0.1516 | 0.6179 | |
| SRP007169 | FANK1 | 92565 | RNAseq | -2.2634 | 0.0000 | |
| SRP064894 | FANK1 | 92565 | RNAseq | -0.9293 | 0.0000 | |
| SRP133303 | FANK1 | 92565 | RNAseq | -0.1233 | 0.6294 | |
| SRP159526 | FANK1 | 92565 | RNAseq | -1.1629 | 0.0085 | |
| SRP193095 | FANK1 | 92565 | RNAseq | -0.7660 | 0.0001 | |
| SRP219564 | FANK1 | 92565 | RNAseq | -0.8348 | 0.1316 | |
| TCGA | FANK1 | 92565 | RNAseq | -0.2631 | 0.0849 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by FANK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FANK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FANK1 | 92565 | 2 | 6 | 22 | |
| GSE20123 | FANK1 | 92565 | 2 | 6 | 22 | |
| GSE43470 | FANK1 | 92565 | 0 | 10 | 33 | |
| GSE46452 | FANK1 | 92565 | 0 | 11 | 48 | |
| GSE47630 | FANK1 | 92565 | 4 | 14 | 22 | |
| GSE54993 | FANK1 | 92565 | 9 | 1 | 60 | |
| GSE54994 | FANK1 | 92565 | 1 | 9 | 43 | |
| GSE60625 | FANK1 | 92565 | 0 | 0 | 11 | |
| GSE74703 | FANK1 | 92565 | 0 | 6 | 30 | |
| GSE74704 | FANK1 | 92565 | 2 | 2 | 16 | |
| TCGA | FANK1 | 92565 | 7 | 27 | 62 |
Total number of gains: 27; Total number of losses: 92; Total Number of normals: 369.
Somatic mutations of FANK1:
Generating mutation plots.
Highly correlated genes for FANK1:
Showing top 20/88 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FANK1 | RPIA | 0.813646 | 3 | 0 | 3 |
| FANK1 | CYP39A1 | 0.743495 | 3 | 0 | 3 |
| FANK1 | RGS12 | 0.71722 | 4 | 0 | 3 |
| FANK1 | ERN1 | 0.714487 | 3 | 0 | 3 |
| FANK1 | D2HGDH | 0.701314 | 4 | 0 | 4 |
| FANK1 | MYO15B | 0.691204 | 3 | 0 | 3 |
| FANK1 | SLC37A1 | 0.686791 | 4 | 0 | 4 |
| FANK1 | CSMD2 | 0.677806 | 3 | 0 | 3 |
| FANK1 | LCORL | 0.674942 | 3 | 0 | 3 |
| FANK1 | BEAN1 | 0.65755 | 3 | 0 | 3 |
| FANK1 | IRGQ | 0.652916 | 3 | 0 | 3 |
| FANK1 | ICAM3 | 0.651015 | 3 | 0 | 3 |
| FANK1 | MIR34A | 0.646123 | 3 | 0 | 3 |
| FANK1 | CDC42BPB | 0.644815 | 4 | 0 | 4 |
| FANK1 | KCNK12 | 0.632125 | 5 | 0 | 3 |
| FANK1 | MFSD1 | 0.630908 | 6 | 0 | 4 |
| FANK1 | CRYGS | 0.624859 | 3 | 0 | 3 |
| FANK1 | NISCH | 0.623593 | 4 | 0 | 3 |
| FANK1 | PAK6 | 0.611544 | 4 | 0 | 3 |
| FANK1 | TDRD6 | 0.610034 | 3 | 0 | 3 |
For details and further investigation, click here
