| Full name: gamma-glutamylamine cyclotransferase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q32.3 | ||
| Entrez ID: 87769 | HGNC ID: HGNC:25100 | Ensembl Gene: ENSG00000134864 | OMIM ID: 613378 |
Expression of GGACT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GGACT | 87769 | 232422_at | -0.2578 | 0.7682 | |
| GSE26886 | GGACT | 87769 | 232422_at | 0.7657 | 0.0035 | |
| GSE45670 | GGACT | 87769 | 232422_at | 0.4651 | 0.1355 | |
| GSE53622 | GGACT | 87769 | 54149 | -0.2088 | 0.2493 | |
| GSE53624 | GGACT | 87769 | 54149 | -0.0922 | 0.5555 | |
| GSE63941 | GGACT | 87769 | 232422_at | -0.4510 | 0.5631 | |
| GSE77861 | GGACT | 87769 | 237869_at | -0.0910 | 0.5190 | |
| SRP007169 | GGACT | 87769 | RNAseq | -0.7921 | 0.1520 | |
| SRP064894 | GGACT | 87769 | RNAseq | 0.1154 | 0.7362 | |
| SRP133303 | GGACT | 87769 | RNAseq | -0.2062 | 0.6180 | |
| SRP159526 | GGACT | 87769 | RNAseq | -0.6644 | 0.1894 | |
| SRP193095 | GGACT | 87769 | RNAseq | -0.8283 | 0.0000 | |
| SRP219564 | GGACT | 87769 | RNAseq | 0.4059 | 0.2646 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GGACT expression:
Note: Click image to view full size file.
Copy number change of GGACT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GGACT | 87769 | 3 | 9 | 18 | |
| GSE20123 | GGACT | 87769 | 3 | 8 | 19 | |
| GSE43470 | GGACT | 87769 | 4 | 12 | 27 | |
| GSE46452 | GGACT | 87769 | 0 | 32 | 27 | |
| GSE47630 | GGACT | 87769 | 3 | 26 | 11 | |
| GSE54993 | GGACT | 87769 | 11 | 4 | 55 | |
| GSE54994 | GGACT | 87769 | 6 | 10 | 37 | |
| GSE60625 | GGACT | 87769 | 0 | 3 | 8 | |
| GSE74703 | GGACT | 87769 | 3 | 10 | 23 | |
| GSE74704 | GGACT | 87769 | 1 | 8 | 11 | |
| TCGA | GGACT | 87769 | 17 | 34 | 45 |
Total number of gains: 51; Total number of losses: 156; Total Number of normals: 281.
Somatic mutations of GGACT:
Generating mutation plots.
Highly correlated genes for GGACT:
Showing all 4 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GGACT | RFXAP | 0.675388 | 3 | 0 | 3 |
| GGACT | GTDC1 | 0.642804 | 3 | 0 | 3 |
| GGACT | AGBL2 | 0.563044 | 3 | 0 | 3 |
| GGACT | ZFAND4 | 0.536273 | 4 | 0 | 3 |
For details and further investigation, click here

