| Full name: glycosyltransferase like domain containing 1 | Alias Symbol: FLJ11753|Hmat-Xa | ||
| Type: protein-coding gene | Cytoband: 2q22.3 | ||
| Entrez ID: 79712 | HGNC ID: HGNC:20887 | Ensembl Gene: ENSG00000121964 | OMIM ID: 610165 |
| Drug and gene relationship at DGIdb | |||
Expression of GTDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTDC1 | 79712 | 219770_at | 0.4915 | 0.2028 | |
| GSE20347 | GTDC1 | 79712 | 219770_at | 0.5229 | 0.0010 | |
| GSE23400 | GTDC1 | 79712 | 220853_at | -0.1331 | 0.0050 | |
| GSE26886 | GTDC1 | 79712 | 219770_at | 1.0614 | 0.0001 | |
| GSE29001 | GTDC1 | 79712 | 219770_at | 0.9478 | 0.0006 | |
| GSE38129 | GTDC1 | 79712 | 219770_at | 0.3442 | 0.0260 | |
| GSE45670 | GTDC1 | 79712 | 219770_at | 0.0493 | 0.8605 | |
| GSE53622 | GTDC1 | 79712 | 61707 | 0.2313 | 0.0081 | |
| GSE53624 | GTDC1 | 79712 | 61707 | 0.3770 | 0.0000 | |
| GSE63941 | GTDC1 | 79712 | 219770_at | -0.5989 | 0.1455 | |
| GSE77861 | GTDC1 | 79712 | 236457_at | -0.1752 | 0.2958 | |
| GSE97050 | GTDC1 | 79712 | A_23_P153945 | 0.2106 | 0.3181 | |
| SRP007169 | GTDC1 | 79712 | RNAseq | 1.6038 | 0.0027 | |
| SRP008496 | GTDC1 | 79712 | RNAseq | 1.4784 | 0.0001 | |
| SRP064894 | GTDC1 | 79712 | RNAseq | 0.4356 | 0.0127 | |
| SRP133303 | GTDC1 | 79712 | RNAseq | 0.3773 | 0.0365 | |
| SRP159526 | GTDC1 | 79712 | RNAseq | 0.6328 | 0.0098 | |
| SRP193095 | GTDC1 | 79712 | RNAseq | 0.4724 | 0.0001 | |
| SRP219564 | GTDC1 | 79712 | RNAseq | 0.4956 | 0.0552 | |
| TCGA | GTDC1 | 79712 | RNAseq | 0.1071 | 0.1224 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by GTDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTDC1 | 79712 | 4 | 3 | 23 | |
| GSE20123 | GTDC1 | 79712 | 3 | 3 | 24 | |
| GSE43470 | GTDC1 | 79712 | 3 | 1 | 39 | |
| GSE46452 | GTDC1 | 79712 | 1 | 4 | 54 | |
| GSE47630 | GTDC1 | 79712 | 5 | 3 | 32 | |
| GSE54993 | GTDC1 | 79712 | 0 | 5 | 65 | |
| GSE54994 | GTDC1 | 79712 | 10 | 2 | 41 | |
| GSE60625 | GTDC1 | 79712 | 0 | 3 | 8 | |
| GSE74703 | GTDC1 | 79712 | 2 | 1 | 33 | |
| GSE74704 | GTDC1 | 79712 | 3 | 1 | 16 | |
| TCGA | GTDC1 | 79712 | 22 | 11 | 63 |
Total number of gains: 53; Total number of losses: 37; Total Number of normals: 398.
Somatic mutations of GTDC1:
Generating mutation plots.
Highly correlated genes for GTDC1:
Showing top 20/427 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTDC1 | SARDH | 0.804948 | 3 | 0 | 3 |
| GTDC1 | ZNF358 | 0.774419 | 3 | 0 | 3 |
| GTDC1 | TMEM18 | 0.75231 | 3 | 0 | 3 |
| GTDC1 | ZNF594 | 0.751419 | 3 | 0 | 3 |
| GTDC1 | CD80 | 0.742729 | 3 | 0 | 3 |
| GTDC1 | RPL26L1 | 0.740544 | 3 | 0 | 3 |
| GTDC1 | MAP1S | 0.732846 | 3 | 0 | 3 |
| GTDC1 | ZNF496 | 0.727921 | 4 | 0 | 4 |
| GTDC1 | PNKP | 0.726832 | 3 | 0 | 3 |
| GTDC1 | CCT6A | 0.723316 | 3 | 0 | 3 |
| GTDC1 | GEMIN5 | 0.721498 | 3 | 0 | 3 |
| GTDC1 | ELFN1 | 0.719587 | 3 | 0 | 3 |
| GTDC1 | ICAM5 | 0.718958 | 3 | 0 | 3 |
| GTDC1 | PSMA2 | 0.716286 | 3 | 0 | 3 |
| GTDC1 | NTPCR | 0.716062 | 4 | 0 | 3 |
| GTDC1 | SIX4 | 0.714644 | 3 | 0 | 3 |
| GTDC1 | TP53I13 | 0.711559 | 4 | 0 | 3 |
| GTDC1 | NFATC4 | 0.709954 | 3 | 0 | 3 |
| GTDC1 | TSNARE1 | 0.70709 | 3 | 0 | 3 |
| GTDC1 | KRTCAP2 | 0.705101 | 3 | 0 | 3 |
For details and further investigation, click here
