| Full name: regulatory factor X associated protein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q13.3 | ||
| Entrez ID: 5994 | HGNC ID: HGNC:9988 | Ensembl Gene: ENSG00000133111 | OMIM ID: 601861 |
| Drug and gene relationship at DGIdb | |||
RFXAP involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04612 | Antigen processing and presentation | |
| hsa05152 | Tuberculosis |
Expression of RFXAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFXAP | 5994 | 229431_at | 0.1269 | 0.8197 | |
| GSE20347 | RFXAP | 5994 | 208492_at | -0.0768 | 0.1884 | |
| GSE23400 | RFXAP | 5994 | 208492_at | -0.0157 | 0.4700 | |
| GSE26886 | RFXAP | 5994 | 229431_at | 1.0743 | 0.0025 | |
| GSE29001 | RFXAP | 5994 | 208492_at | -0.1246 | 0.2157 | |
| GSE38129 | RFXAP | 5994 | 208492_at | -0.0731 | 0.3602 | |
| GSE45670 | RFXAP | 5994 | 229431_at | -0.5031 | 0.1284 | |
| GSE53622 | RFXAP | 5994 | 109924 | 0.1848 | 0.0591 | |
| GSE53624 | RFXAP | 5994 | 109924 | 0.3656 | 0.0221 | |
| GSE63941 | RFXAP | 5994 | 229431_at | 0.1993 | 0.7900 | |
| GSE77861 | RFXAP | 5994 | 208492_at | -0.0230 | 0.8905 | |
| GSE97050 | RFXAP | 5994 | A_23_P315789 | -0.0523 | 0.8128 | |
| SRP007169 | RFXAP | 5994 | RNAseq | 1.1199 | 0.1671 | |
| SRP064894 | RFXAP | 5994 | RNAseq | 0.3562 | 0.0983 | |
| SRP133303 | RFXAP | 5994 | RNAseq | 0.1202 | 0.5346 | |
| SRP159526 | RFXAP | 5994 | RNAseq | 0.0994 | 0.7968 | |
| SRP193095 | RFXAP | 5994 | RNAseq | 0.0792 | 0.5644 | |
| SRP219564 | RFXAP | 5994 | RNAseq | -0.3222 | 0.5648 | |
| TCGA | RFXAP | 5994 | RNAseq | -0.0956 | 0.2773 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RFXAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFXAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFXAP | 5994 | 0 | 16 | 14 | |
| GSE20123 | RFXAP | 5994 | 0 | 15 | 15 | |
| GSE43470 | RFXAP | 5994 | 2 | 14 | 27 | |
| GSE46452 | RFXAP | 5994 | 0 | 33 | 26 | |
| GSE47630 | RFXAP | 5994 | 2 | 27 | 11 | |
| GSE54993 | RFXAP | 5994 | 12 | 2 | 56 | |
| GSE54994 | RFXAP | 5994 | 1 | 17 | 35 | |
| GSE60625 | RFXAP | 5994 | 0 | 3 | 8 | |
| GSE74703 | RFXAP | 5994 | 2 | 11 | 23 | |
| GSE74704 | RFXAP | 5994 | 0 | 12 | 8 | |
| TCGA | RFXAP | 5994 | 7 | 40 | 49 |
Total number of gains: 26; Total number of losses: 190; Total Number of normals: 272.
Somatic mutations of RFXAP:
Generating mutation plots.
Highly correlated genes for RFXAP:
Showing top 20/437 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFXAP | DHRSX | 0.790036 | 3 | 0 | 3 |
| RFXAP | DCUN1D2 | 0.787782 | 3 | 0 | 3 |
| RFXAP | POLR2I | 0.774351 | 3 | 0 | 3 |
| RFXAP | ZCCHC3 | 0.768628 | 3 | 0 | 3 |
| RFXAP | ZBTB12 | 0.753959 | 3 | 0 | 3 |
| RFXAP | SELPLG | 0.741226 | 3 | 0 | 3 |
| RFXAP | SLC37A3 | 0.738546 | 3 | 0 | 3 |
| RFXAP | WDR81 | 0.734893 | 3 | 0 | 3 |
| RFXAP | ZSCAN21 | 0.725632 | 3 | 0 | 3 |
| RFXAP | ZBTB26 | 0.7203 | 6 | 0 | 6 |
| RFXAP | EID1 | 0.714428 | 4 | 0 | 3 |
| RFXAP | ALG10 | 0.712617 | 3 | 0 | 3 |
| RFXAP | TRMT12 | 0.709017 | 3 | 0 | 3 |
| RFXAP | C1orf131 | 0.707891 | 3 | 0 | 3 |
| RFXAP | C15orf61 | 0.707199 | 4 | 0 | 4 |
| RFXAP | SGTB | 0.706449 | 3 | 0 | 3 |
| RFXAP | ZNF41 | 0.705122 | 3 | 0 | 3 |
| RFXAP | PNKP | 0.704807 | 3 | 0 | 3 |
| RFXAP | USP19 | 0.700028 | 4 | 0 | 3 |
| RFXAP | MID1IP1 | 0.698934 | 4 | 0 | 3 |
For details and further investigation, click here
