KLHL38

 

Full name: kelch like family member 38 Alias Symbol: C8ORFK36
Type: protein-coding gene Cytoband: 8q24.13
Entrez ID: 340359 HGNC ID: HGNC:34435 Ensembl Gene: ENSG00000175946 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of KLHL38:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 KLHL38 340359 68763 0.3912 0.0059
GSE53624 KLHL38 340359 68763 0.0661 0.4427
GSE97050 KLHL38 340359 A_33_P3288491 -0.6306 0.1812
SRP133303 KLHL38 340359 RNAseq 0.3154 0.0958
SRP159526 KLHL38 340359 RNAseq 1.4167 0.1014
SRP219564 KLHL38 340359 RNAseq 0.9476 0.1864
TCGA KLHL38 340359 RNAseq -1.0282 0.0368

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by KLHL38 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KLHL38:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KLHL38 340359 19 0 11
GSE20123 KLHL38 340359 20 0 10
GSE43470 KLHL38 340359 22 0 21
GSE46452 KLHL38 340359 27 0 32
GSE47630 KLHL38 340359 24 0 16
GSE54993 KLHL38 340359 0 21 49
GSE54994 KLHL38 340359 37 1 15
GSE60625 KLHL38 340359 0 4 7
GSE74703 KLHL38 340359 19 0 17
GSE74704 KLHL38 340359 13 0 7
TCGA KLHL38 340359 67 1 28

Total number of gains: 248; Total number of losses: 27; Total Number of normals: 213.  

 

Somatic mutations of KLHL38:

 

Generating mutation plots.

 

Highly correlated genes for KLHL38:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KLHL38GOLGA6L60.681191303
KLHL38MMP210.607653303
KLHL38ACRV10.571128303
KLHL38OR4A150.533571303

For details and further investigation, click here