| Full name: acrosomal vesicle protein 1 | Alias Symbol: SPACA2|SP-10|D11S4365 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 56 | HGNC ID: HGNC:127 | Ensembl Gene: ENSG00000134940 | OMIM ID: 102525 |
| Drug and gene relationship at DGIdb | |||
Expression of ACRV1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACRV1 | 56 | 207969_x_at | -0.0020 | 0.9959 | |
| GSE20347 | ACRV1 | 56 | 207990_x_at | -0.0970 | 0.2467 | |
| GSE23400 | ACRV1 | 56 | 207969_x_at | -0.2515 | 0.0000 | |
| GSE26886 | ACRV1 | 56 | 207969_x_at | -0.2210 | 0.0121 | |
| GSE29001 | ACRV1 | 56 | 207969_x_at | -0.3437 | 0.1915 | |
| GSE38129 | ACRV1 | 56 | 207990_x_at | -0.1354 | 0.1458 | |
| GSE45670 | ACRV1 | 56 | 207969_x_at | 0.0388 | 0.7494 | |
| GSE53622 | ACRV1 | 56 | 25949 | 0.1111 | 0.3372 | |
| GSE53624 | ACRV1 | 56 | 25949 | 0.2274 | 0.0076 | |
| GSE63941 | ACRV1 | 56 | 207969_x_at | 0.1542 | 0.4171 | |
| GSE77861 | ACRV1 | 56 | 207990_x_at | -0.3114 | 0.0221 | |
| GSE97050 | ACRV1 | 56 | A_23_P202894 | 0.0748 | 0.8049 | |
| TCGA | ACRV1 | 56 | RNAseq | 2.1124 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ACRV1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACRV1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACRV1 | 56 | 0 | 13 | 17 | |
| GSE20123 | ACRV1 | 56 | 0 | 13 | 17 | |
| GSE43470 | ACRV1 | 56 | 2 | 7 | 34 | |
| GSE46452 | ACRV1 | 56 | 3 | 26 | 30 | |
| GSE47630 | ACRV1 | 56 | 2 | 19 | 19 | |
| GSE54993 | ACRV1 | 56 | 10 | 0 | 60 | |
| GSE54994 | ACRV1 | 56 | 5 | 19 | 29 | |
| GSE60625 | ACRV1 | 56 | 0 | 3 | 8 | |
| GSE74703 | ACRV1 | 56 | 1 | 5 | 30 | |
| GSE74704 | ACRV1 | 56 | 0 | 9 | 11 | |
| TCGA | ACRV1 | 56 | 7 | 50 | 39 |
Total number of gains: 30; Total number of losses: 164; Total Number of normals: 294.
Somatic mutations of ACRV1:
Generating mutation plots.
Highly correlated genes for ACRV1:
Showing top 20/912 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACRV1 | OR2D2 | 0.7904 | 3 | 0 | 3 |
| ACRV1 | OR4A15 | 0.751596 | 3 | 0 | 3 |
| ACRV1 | TRIM43 | 0.736395 | 3 | 0 | 3 |
| ACRV1 | CYP11B1 | 0.732089 | 5 | 0 | 5 |
| ACRV1 | FNDC9 | 0.728641 | 3 | 0 | 3 |
| ACRV1 | HTR4 | 0.722251 | 6 | 0 | 6 |
| ACRV1 | OR2B11 | 0.721488 | 3 | 0 | 3 |
| ACRV1 | LYZL2 | 0.720378 | 3 | 0 | 3 |
| ACRV1 | ZNF81 | 0.720099 | 3 | 0 | 3 |
| ACRV1 | KIR2DS2 | 0.719332 | 5 | 0 | 5 |
| ACRV1 | ITGA10 | 0.718599 | 6 | 0 | 6 |
| ACRV1 | PAX3 | 0.718011 | 5 | 0 | 5 |
| ACRV1 | RNF157 | 0.714294 | 4 | 0 | 4 |
| ACRV1 | SHROOM4 | 0.708689 | 3 | 0 | 3 |
| ACRV1 | RENBP | 0.700642 | 3 | 0 | 3 |
| ACRV1 | GJA8 | 0.700083 | 5 | 0 | 5 |
| ACRV1 | OR56A5 | 0.699032 | 3 | 0 | 3 |
| ACRV1 | SCGB1D2 | 0.695755 | 3 | 0 | 3 |
| ACRV1 | PRAMEF5 | 0.693585 | 3 | 0 | 3 |
| ACRV1 | CBLN1 | 0.688994 | 5 | 0 | 4 |
For details and further investigation, click here
