LHFPL3

 

Full name: LHFPL tetraspan subfamily member 3 Alias Symbol: 
Type: protein-coding gene Cytoband: 7q22.2-q22.3
Entrez ID: 375612 HGNC ID: HGNC:6589 Ensembl Gene: ENSG00000187416 OMIM ID: 609719
Drug and gene relationship at DGIdb

 

Expression of LHFPL3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LHFPL3 375612 236761_at 0.0360 0.9312
GSE26886 LHFPL3 375612 236761_at -0.0223 0.8635
GSE45670 LHFPL3 375612 236761_at 0.0548 0.6275
GSE53622 LHFPL3 375612 35524 -0.0680 0.4779
GSE53624 LHFPL3 375612 35524 -0.1068 0.2474
GSE63941 LHFPL3 375612 236761_at 0.1050 0.3314
GSE77861 LHFPL3 375612 236761_at -0.1545 0.0683
TCGA LHFPL3 375612 RNAseq -1.8657 0.0303

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by LHFPL3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LHFPL3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LHFPL3 375612 14 0 16
GSE20123 LHFPL3 375612 14 0 16
GSE43470 LHFPL3 375612 7 1 35
GSE46452 LHFPL3 375612 10 1 48
GSE47630 LHFPL3 375612 7 3 30
GSE54993 LHFPL3 375612 2 10 58
GSE54994 LHFPL3 375612 16 3 34
GSE60625 LHFPL3 375612 0 0 11
GSE74703 LHFPL3 375612 7 1 28
GSE74704 LHFPL3 375612 9 0 11
TCGA LHFPL3 375612 54 7 35

Total number of gains: 140; Total number of losses: 26; Total Number of normals: 322.  

 

Somatic mutations of LHFPL3:

 

Generating mutation plots.

 

Highly correlated genes for LHFPL3:

 

Showing all 5 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LHFPL3LINC005270.590062303
LHFPL3RAB3C0.561221303
LHFPL3BCAN0.549976403
LHFPL3FGF10-AS10.547817403
LHFPL3CDH90.523413403

For details and further investigation, click here