MAEL

 

Full name: maelstrom spermatogenic transposon silencer Alias Symbol: FLJ14904|CT128|SPATA35
Type: protein-coding gene Cytoband: 1q24.1
Entrez ID: 84944 HGNC ID: HGNC:25929 Ensembl Gene: ENSG00000143194 OMIM ID: 611368
Drug and gene relationship at DGIdb

 

Expression of MAEL:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MAEL 84944 229475_at 0.1547 0.9703
GSE26886 MAEL 84944 229475_at 0.0207 0.8263
GSE45670 MAEL 84944 229475_at 0.5308 0.4240
GSE53622 MAEL 84944 1062 -0.0235 0.9379
GSE53624 MAEL 84944 1062 0.3347 0.2351
GSE63941 MAEL 84944 229475_at 0.1635 0.3814
GSE77861 MAEL 84944 229475_at -0.2006 0.0664
TCGA MAEL 84944 RNAseq 0.8475 0.3555

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by MAEL expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MAEL:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MAEL 84944 11 1 18
GSE20123 MAEL 84944 11 1 18
GSE43470 MAEL 84944 7 2 34
GSE46452 MAEL 84944 2 1 56
GSE47630 MAEL 84944 14 0 26
GSE54993 MAEL 84944 0 5 65
GSE54994 MAEL 84944 16 0 37
GSE60625 MAEL 84944 0 0 11
GSE74703 MAEL 84944 7 2 27
GSE74704 MAEL 84944 5 0 15
TCGA MAEL 84944 44 3 49

Total number of gains: 117; Total number of losses: 15; Total Number of normals: 356.  

 

Somatic mutations of MAEL:

 

Generating mutation plots.

 

Highly correlated genes for MAEL:

 

Showing all 3 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MAELCCDC1590.65364303
MAELMYLK40.62212303
MAELGAS6-AS10.532929403

For details and further investigation, click here