| Full name: coiled-coil domain containing 159 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 126075 | HGNC ID: HGNC:26996 | Ensembl Gene: ENSG00000183401 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC159:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC159 | 126075 | 227043_at | -0.1828 | 0.6955 | |
| GSE26886 | CCDC159 | 126075 | 227043_at | 0.0592 | 0.7370 | |
| GSE45670 | CCDC159 | 126075 | 227043_at | -0.1008 | 0.2629 | |
| GSE53622 | CCDC159 | 126075 | 17381 | -0.7608 | 0.0000 | |
| GSE53624 | CCDC159 | 126075 | 17381 | -0.8044 | 0.0000 | |
| GSE63941 | CCDC159 | 126075 | 227043_at | 0.1344 | 0.5712 | |
| GSE77861 | CCDC159 | 126075 | 227043_at | -0.1904 | 0.2482 | |
| GSE97050 | CCDC159 | 126075 | A_24_P75920 | -0.3246 | 0.2151 | |
| SRP007169 | CCDC159 | 126075 | RNAseq | -1.9114 | 0.0001 | |
| SRP064894 | CCDC159 | 126075 | RNAseq | 0.1551 | 0.5508 | |
| SRP133303 | CCDC159 | 126075 | RNAseq | -0.4226 | 0.0500 | |
| SRP159526 | CCDC159 | 126075 | RNAseq | -0.3045 | 0.3342 | |
| SRP193095 | CCDC159 | 126075 | RNAseq | -0.7334 | 0.0000 | |
| SRP219564 | CCDC159 | 126075 | RNAseq | -0.0742 | 0.8208 | |
| TCGA | CCDC159 | 126075 | RNAseq | -0.4201 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CCDC159 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC159:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC159 | 126075 | 4 | 2 | 24 | |
| GSE20123 | CCDC159 | 126075 | 3 | 1 | 26 | |
| GSE43470 | CCDC159 | 126075 | 2 | 6 | 35 | |
| GSE46452 | CCDC159 | 126075 | 47 | 1 | 11 | |
| GSE47630 | CCDC159 | 126075 | 4 | 7 | 29 | |
| GSE54993 | CCDC159 | 126075 | 16 | 3 | 51 | |
| GSE54994 | CCDC159 | 126075 | 6 | 13 | 34 | |
| GSE60625 | CCDC159 | 126075 | 9 | 0 | 2 | |
| GSE74703 | CCDC159 | 126075 | 2 | 4 | 30 | |
| GSE74704 | CCDC159 | 126075 | 0 | 1 | 19 | |
| TCGA | CCDC159 | 126075 | 16 | 12 | 68 |
Total number of gains: 109; Total number of losses: 50; Total Number of normals: 329.
Somatic mutations of CCDC159:
Generating mutation plots.
Highly correlated genes for CCDC159:
Showing top 20/679 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC159 | EPC1 | 0.821932 | 3 | 0 | 3 |
| CCDC159 | ZBTB10 | 0.808461 | 3 | 0 | 3 |
| CCDC159 | ZNF358 | 0.783419 | 3 | 0 | 3 |
| CCDC159 | UBE2R2 | 0.778289 | 3 | 0 | 3 |
| CCDC159 | MYRIP | 0.774521 | 3 | 0 | 3 |
| CCDC159 | NR3C2 | 0.771096 | 3 | 0 | 3 |
| CCDC159 | ZNF844 | 0.754232 | 3 | 0 | 3 |
| CCDC159 | AFF3 | 0.753655 | 3 | 0 | 3 |
| CCDC159 | CLEC3B | 0.753427 | 3 | 0 | 3 |
| CCDC159 | HDAC11 | 0.751375 | 3 | 0 | 3 |
| CCDC159 | ZNF214 | 0.750066 | 3 | 0 | 3 |
| CCDC159 | USP9X | 0.741652 | 4 | 0 | 4 |
| CCDC159 | XRRA1 | 0.741272 | 3 | 0 | 3 |
| CCDC159 | CYP4V2 | 0.737785 | 3 | 0 | 3 |
| CCDC159 | GPR108 | 0.735988 | 3 | 0 | 3 |
| CCDC159 | ADH1C | 0.728401 | 4 | 0 | 4 |
| CCDC159 | UBE2J1 | 0.726325 | 3 | 0 | 3 |
| CCDC159 | SPHK2 | 0.724049 | 3 | 0 | 3 |
| CCDC159 | KCTD10 | 0.722908 | 3 | 0 | 3 |
| CCDC159 | TCF21 | 0.720607 | 4 | 0 | 4 |
For details and further investigation, click here
