OR2B3

 

Full name: olfactory receptor family 2 subfamily B member 3 Alias Symbol: OR6-4
Type: protein-coding gene Cytoband: 6p22.1
Entrez ID: 442184 HGNC ID: HGNC:8238 Ensembl Gene: ENSG00000204703 OMIM ID: 
Drug and gene relationship at DGIdb

 

OR2B3 involved pathways:

KEGG pathway Description View
hsa04740Olfactory transduction

 

Expression of OR2B3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OR2B3 442184 234903_at -0.0909 0.7302
GSE26886 OR2B3 442184 234903_at -0.1305 0.1791
GSE45670 OR2B3 442184 234903_at 0.0291 0.7335
GSE53622 OR2B3 442184 79955 -0.0642 0.6059
GSE53624 OR2B3 442184 79955 0.1207 0.1494
GSE63941 OR2B3 442184 234903_at -0.1125 0.3460
GSE77861 OR2B3 442184 234903_at -0.0199 0.8410
TCGA OR2B3 442184 RNAseq 1.6482 0.4883

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by OR2B3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of OR2B3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OR2B3 442184 3 2 25
GSE20123 OR2B3 442184 3 2 25
GSE43470 OR2B3 442184 5 0 38
GSE46452 OR2B3 442184 1 10 48
GSE47630 OR2B3 442184 7 4 29
GSE54993 OR2B3 442184 2 1 67
GSE54994 OR2B3 442184 11 4 38
GSE60625 OR2B3 442184 0 1 10
GSE74703 OR2B3 442184 5 0 31
GSE74704 OR2B3 442184 0 1 19
TCGA OR2B3 442184 16 18 62

Total number of gains: 53; Total number of losses: 43; Total Number of normals: 392.  

 

Somatic mutations of OR2B3:

 

Generating mutation plots.

 

Highly correlated genes for OR2B3:

 

Showing all 2 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OR2B3LRRC520.652575303
OR2B3WNT60.55777403

For details and further investigation, click here