| Full name: leucine rich repeat containing 52 | Alias Symbol: FLJ25811 | ||
| Type: protein-coding gene | Cytoband: 1q24.1 | ||
| Entrez ID: 440699 | HGNC ID: HGNC:32156 | Ensembl Gene: ENSG00000162763 | OMIM ID: 615218 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC52:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC52 | 440699 | 1556484_at | -0.0419 | 0.8621 | |
| GSE26886 | LRRC52 | 440699 | 1556484_at | 0.0599 | 0.5735 | |
| GSE45670 | LRRC52 | 440699 | 1556484_at | 0.0308 | 0.7902 | |
| GSE53622 | LRRC52 | 440699 | 73890 | 0.2705 | 0.0127 | |
| GSE53624 | LRRC52 | 440699 | 114051 | -0.0952 | 0.3243 | |
| GSE63941 | LRRC52 | 440699 | 1556484_at | 0.0482 | 0.7368 | |
| GSE77861 | LRRC52 | 440699 | 1556484_at | -0.0657 | 0.5739 | |
| TCGA | LRRC52 | 440699 | RNAseq | -3.6878 | 0.0100 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LRRC52 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC52:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC52 | 440699 | 10 | 2 | 18 | |
| GSE20123 | LRRC52 | 440699 | 10 | 2 | 18 | |
| GSE43470 | LRRC52 | 440699 | 7 | 2 | 34 | |
| GSE46452 | LRRC52 | 440699 | 2 | 1 | 56 | |
| GSE47630 | LRRC52 | 440699 | 14 | 0 | 26 | |
| GSE54993 | LRRC52 | 440699 | 0 | 5 | 65 | |
| GSE54994 | LRRC52 | 440699 | 16 | 0 | 37 | |
| GSE60625 | LRRC52 | 440699 | 0 | 0 | 11 | |
| GSE74703 | LRRC52 | 440699 | 7 | 2 | 27 | |
| GSE74704 | LRRC52 | 440699 | 4 | 1 | 15 | |
| TCGA | LRRC52 | 440699 | 44 | 3 | 49 |
Total number of gains: 114; Total number of losses: 18; Total Number of normals: 356.
Somatic mutations of LRRC52:
Generating mutation plots.
Highly correlated genes for LRRC52:
Showing top 20/35 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC52 | OR51B5 | 0.678824 | 3 | 0 | 3 |
| LRRC52 | OR2B3 | 0.652575 | 3 | 0 | 3 |
| LRRC52 | SGK2 | 0.633903 | 3 | 0 | 3 |
| LRRC52 | CHRM2 | 0.610823 | 3 | 0 | 3 |
| LRRC52 | DGKK | 0.605364 | 4 | 0 | 3 |
| LRRC52 | LMX1A | 0.605281 | 3 | 0 | 3 |
| LRRC52 | KRT73 | 0.600591 | 5 | 0 | 4 |
| LRRC52 | MYL1 | 0.60054 | 4 | 0 | 4 |
| LRRC52 | BCAN | 0.595441 | 3 | 0 | 3 |
| LRRC52 | KRTAP5-8 | 0.586827 | 3 | 0 | 3 |
| LRRC52 | FHAD1 | 0.565194 | 3 | 0 | 3 |
| LRRC52 | ADRB3 | 0.563039 | 4 | 0 | 3 |
| LRRC52 | GRPR | 0.560314 | 4 | 0 | 4 |
| LRRC52 | LINC00689 | 0.559063 | 3 | 0 | 3 |
| LRRC52 | DLEU7 | 0.555493 | 4 | 0 | 3 |
| LRRC52 | ACTL7A | 0.551564 | 5 | 0 | 4 |
| LRRC52 | HTR1A | 0.549693 | 4 | 0 | 3 |
| LRRC52 | TNK2-AS1 | 0.548626 | 4 | 0 | 3 |
| LRRC52 | WFDC9 | 0.545925 | 4 | 0 | 3 |
| LRRC52 | KCNG4 | 0.545816 | 4 | 0 | 4 |
For details and further investigation, click here
