THSD7B

 

Full name: thrombospondin type 1 domain containing 7B Alias Symbol: KIAA1679
Type: protein-coding gene Cytoband: 2q22.1
Entrez ID: 80731 HGNC ID: HGNC:29348 Ensembl Gene: ENSG00000144229 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of THSD7B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 THSD7B 80731 232327_at 0.0234 0.9718
GSE26886 THSD7B 80731 232327_at 0.3152 0.5387
GSE45670 THSD7B 80731 232327_at 0.0342 0.9555
GSE53622 THSD7B 80731 17891 0.1537 0.5507
GSE53624 THSD7B 80731 17891 -0.5211 0.0056
GSE63941 THSD7B 80731 232327_at 0.7225 0.4655
GSE77861 THSD7B 80731 232327_at -0.1277 0.4048
SRP133303 THSD7B 80731 RNAseq 0.1895 0.7736
SRP159526 THSD7B 80731 RNAseq 1.5657 0.0569
TCGA THSD7B 80731 RNAseq -0.0770 0.8891

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by THSD7B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of THSD7B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 THSD7B 80731 4 4 22
GSE20123 THSD7B 80731 4 4 22
GSE43470 THSD7B 80731 4 1 38
GSE46452 THSD7B 80731 1 4 54
GSE47630 THSD7B 80731 5 2 33
GSE54993 THSD7B 80731 0 6 64
GSE54994 THSD7B 80731 9 0 44
GSE60625 THSD7B 80731 0 3 8
GSE74703 THSD7B 80731 3 1 32
GSE74704 THSD7B 80731 2 1 17
TCGA THSD7B 80731 21 14 61

Total number of gains: 53; Total number of losses: 40; Total Number of normals: 395.  

 

Somatic mutations of THSD7B:

 

Generating mutation plots.

 

Highly correlated genes for THSD7B:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
THSD7BRBP40.595224303
THSD7BEMX20.5915403
THSD7BPCDH190.550547603
THSD7BCADM10.537824503

For details and further investigation, click here