| Full name: cell adhesion molecule 1 | Alias Symbol: NECL2|ST17|BL2|SYNCAM|IGSF4A|Necl-2|SYNCAM1|RA175 | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 23705 | HGNC ID: HGNC:5951 | Ensembl Gene: ENSG00000182985 | OMIM ID: 605686 |
| Drug and gene relationship at DGIdb | |||
Expression of CADM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CADM1 | 23705 | 209030_s_at | -0.7866 | 0.4479 | |
| GSE20347 | CADM1 | 23705 | 209030_s_at | -0.6378 | 0.0216 | |
| GSE23400 | CADM1 | 23705 | 209031_at | -0.7005 | 0.0000 | |
| GSE26886 | CADM1 | 23705 | 209030_s_at | 0.3113 | 0.4001 | |
| GSE29001 | CADM1 | 23705 | 209031_at | -1.0738 | 0.0676 | |
| GSE38129 | CADM1 | 23705 | 209030_s_at | -0.6022 | 0.0141 | |
| GSE45670 | CADM1 | 23705 | 209031_at | -1.5775 | 0.0131 | |
| GSE53622 | CADM1 | 23705 | 65319 | -1.1007 | 0.0000 | |
| GSE53624 | CADM1 | 23705 | 65319 | -1.1696 | 0.0000 | |
| GSE63941 | CADM1 | 23705 | 209030_s_at | -1.6722 | 0.1679 | |
| GSE77861 | CADM1 | 23705 | 209030_s_at | -0.3802 | 0.1569 | |
| GSE97050 | CADM1 | 23705 | A_33_P3745146 | -0.5150 | 0.3181 | |
| SRP007169 | CADM1 | 23705 | RNAseq | 0.2289 | 0.7603 | |
| SRP008496 | CADM1 | 23705 | RNAseq | 0.9491 | 0.0535 | |
| SRP064894 | CADM1 | 23705 | RNAseq | -1.4567 | 0.0000 | |
| SRP133303 | CADM1 | 23705 | RNAseq | -0.0731 | 0.8056 | |
| SRP159526 | CADM1 | 23705 | RNAseq | 1.9529 | 0.0071 | |
| SRP193095 | CADM1 | 23705 | RNAseq | -0.3502 | 0.1532 | |
| SRP219564 | CADM1 | 23705 | RNAseq | -0.6072 | 0.2661 | |
| TCGA | CADM1 | 23705 | RNAseq | -0.3520 | 0.0626 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by CADM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CADM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CADM1 | 23705 | 0 | 13 | 17 | |
| GSE20123 | CADM1 | 23705 | 0 | 13 | 17 | |
| GSE43470 | CADM1 | 23705 | 2 | 7 | 34 | |
| GSE46452 | CADM1 | 23705 | 3 | 26 | 30 | |
| GSE47630 | CADM1 | 23705 | 2 | 19 | 19 | |
| GSE54993 | CADM1 | 23705 | 10 | 0 | 60 | |
| GSE54994 | CADM1 | 23705 | 5 | 19 | 29 | |
| GSE60625 | CADM1 | 23705 | 0 | 3 | 8 | |
| GSE74703 | CADM1 | 23705 | 1 | 5 | 30 | |
| GSE74704 | CADM1 | 23705 | 0 | 9 | 11 | |
| TCGA | CADM1 | 23705 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of CADM1:
Generating mutation plots.
Highly correlated genes for CADM1:
Showing top 20/481 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CADM1 | DYM | 0.684708 | 4 | 0 | 4 |
| CADM1 | ZNF43 | 0.67395 | 5 | 0 | 5 |
| CADM1 | CNN1 | 0.672208 | 4 | 0 | 4 |
| CADM1 | SATB1 | 0.660705 | 11 | 0 | 9 |
| CADM1 | CELF2 | 0.646902 | 11 | 0 | 11 |
| CADM1 | ZBTB20 | 0.646293 | 7 | 0 | 6 |
| CADM1 | TMEM170B | 0.643062 | 7 | 0 | 6 |
| CADM1 | MRVI1 | 0.638459 | 5 | 0 | 4 |
| CADM1 | SORBS1 | 0.637877 | 5 | 0 | 4 |
| CADM1 | SH3BGRL | 0.636655 | 11 | 0 | 10 |
| CADM1 | SMOC2 | 0.635737 | 6 | 0 | 5 |
| CADM1 | PBX1 | 0.633107 | 12 | 0 | 10 |
| CADM1 | NEGR1 | 0.632566 | 5 | 0 | 5 |
| CADM1 | ANO5 | 0.630719 | 5 | 0 | 5 |
| CADM1 | MAGI2-AS3 | 0.629508 | 4 | 0 | 4 |
| CADM1 | TNRC6C | 0.627936 | 3 | 0 | 3 |
| CADM1 | PGM5 | 0.626289 | 6 | 0 | 6 |
| CADM1 | CYP2U1 | 0.626211 | 6 | 0 | 5 |
| CADM1 | ZNF704 | 0.62482 | 6 | 0 | 5 |
| CADM1 | HLF | 0.623306 | 10 | 0 | 9 |
For details and further investigation, click here
