| Full name: empty spiracles homeobox 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q26.11 | ||
| Entrez ID: 2018 | HGNC ID: HGNC:3341 | Ensembl Gene: ENSG00000170370 | OMIM ID: 600035 |
| Drug and gene relationship at DGIdb | |||
Expression of EMX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EMX2 | 2018 | 221950_at | -0.1575 | 0.5327 | |
| GSE20347 | EMX2 | 2018 | 221950_at | -0.0175 | 0.7732 | |
| GSE23400 | EMX2 | 2018 | 221950_at | -0.0620 | 0.0058 | |
| GSE26886 | EMX2 | 2018 | 221950_at | 0.4716 | 0.1523 | |
| GSE29001 | EMX2 | 2018 | 221950_at | 0.3228 | 0.5336 | |
| GSE38129 | EMX2 | 2018 | 221950_at | -0.1091 | 0.2840 | |
| GSE45670 | EMX2 | 2018 | 221950_at | -0.0796 | 0.7980 | |
| GSE53622 | EMX2 | 2018 | 104302 | -1.0156 | 0.0000 | |
| GSE53624 | EMX2 | 2018 | 104302 | -1.1050 | 0.0000 | |
| GSE63941 | EMX2 | 2018 | 221950_at | 0.5727 | 0.4625 | |
| GSE77861 | EMX2 | 2018 | 221950_at | 0.0239 | 0.8599 | |
| SRP133303 | EMX2 | 2018 | RNAseq | -0.4058 | 0.0169 | |
| SRP159526 | EMX2 | 2018 | RNAseq | 0.1933 | 0.8051 | |
| SRP219564 | EMX2 | 2018 | RNAseq | 0.4555 | 0.4651 | |
| TCGA | EMX2 | 2018 | RNAseq | 1.0456 | 0.0889 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by EMX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EMX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EMX2 | 2018 | 1 | 7 | 22 | |
| GSE20123 | EMX2 | 2018 | 1 | 7 | 22 | |
| GSE43470 | EMX2 | 2018 | 0 | 9 | 34 | |
| GSE46452 | EMX2 | 2018 | 0 | 11 | 48 | |
| GSE47630 | EMX2 | 2018 | 2 | 14 | 24 | |
| GSE54993 | EMX2 | 2018 | 8 | 0 | 62 | |
| GSE54994 | EMX2 | 2018 | 1 | 9 | 43 | |
| GSE60625 | EMX2 | 2018 | 0 | 0 | 11 | |
| GSE74703 | EMX2 | 2018 | 0 | 6 | 30 | |
| GSE74704 | EMX2 | 2018 | 1 | 3 | 16 | |
| TCGA | EMX2 | 2018 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 94; Total Number of normals: 376.
Somatic mutations of EMX2:
Generating mutation plots.
Highly correlated genes for EMX2:
Showing top 20/35 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EMX2 | RELN | 0.688921 | 3 | 0 | 3 |
| EMX2 | BEX1 | 0.676152 | 4 | 0 | 3 |
| EMX2 | IRX1 | 0.658202 | 3 | 0 | 3 |
| EMX2 | EFHD1 | 0.650875 | 4 | 0 | 3 |
| EMX2 | C8orf34 | 0.627607 | 3 | 0 | 3 |
| EMX2 | CSF1 | 0.610795 | 3 | 0 | 3 |
| EMX2 | USP29 | 0.603993 | 4 | 0 | 3 |
| EMX2 | WDR19 | 0.599392 | 3 | 0 | 3 |
| EMX2 | NPY1R | 0.594472 | 5 | 0 | 3 |
| EMX2 | IRS4 | 0.592912 | 3 | 0 | 3 |
| EMX2 | THSD7B | 0.5915 | 4 | 0 | 3 |
| EMX2 | GPC5 | 0.590316 | 4 | 0 | 3 |
| EMX2 | GNAL | 0.582385 | 4 | 0 | 3 |
| EMX2 | BEGAIN | 0.580674 | 4 | 0 | 3 |
| EMX2 | MYEF2 | 0.562908 | 4 | 0 | 3 |
| EMX2 | TRPC1 | 0.559359 | 4 | 0 | 3 |
| EMX2 | ACSS3 | 0.559048 | 4 | 0 | 3 |
| EMX2 | SHE | 0.552107 | 4 | 0 | 3 |
| EMX2 | BMPER | 0.549852 | 5 | 0 | 4 |
| EMX2 | DACH1 | 0.546218 | 6 | 0 | 3 |
For details and further investigation, click here
