TKTL2

 

Full name: transketolase like 2 Alias Symbol: FLJ32975|DKFZP434L1717
Type: protein-coding gene Cytoband: 4q32.2
Entrez ID: 84076 HGNC ID: HGNC:25313 Ensembl Gene: ENSG00000151005 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TKTL2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TKTL2 84076 223829_at 0.2431 0.2856
GSE26886 TKTL2 84076 223829_at -0.0654 0.5223
GSE45670 TKTL2 84076 223829_at 0.0755 0.4193
GSE53622 TKTL2 84076 97936 -0.0419 0.7789
GSE53624 TKTL2 84076 97936 0.1241 0.2191
GSE63941 TKTL2 84076 223829_at 0.0078 0.9651
GSE77861 TKTL2 84076 223829_at -0.1174 0.1763
TCGA TKTL2 84076 RNAseq 2.3108 0.0672

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TKTL2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TKTL2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TKTL2 84076 0 11 19
GSE20123 TKTL2 84076 0 11 19
GSE43470 TKTL2 84076 0 14 29
GSE46452 TKTL2 84076 1 36 22
GSE47630 TKTL2 84076 0 22 18
GSE54993 TKTL2 84076 10 0 60
GSE54994 TKTL2 84076 1 12 40
GSE60625 TKTL2 84076 0 0 11
GSE74703 TKTL2 84076 0 12 24
GSE74704 TKTL2 84076 0 5 15
TCGA TKTL2 84076 10 34 52

Total number of gains: 22; Total number of losses: 157; Total Number of normals: 309.  

 

Somatic mutations of TKTL2:

 

Generating mutation plots.

 

Highly correlated genes for TKTL2:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TKTL2KDF10.661508303
TKTL2ZFP420.628113303
TKTL2ACTL100.620902303
TKTL2CEP170B0.609806303
TKTL2DPYS0.542259403
TKTL2C7orf610.527819403

For details and further investigation, click here