| Full name: ZFP42 zinc finger protein | Alias Symbol: REX1|ZNF754 | ||
| Type: protein-coding gene | Cytoband: 4q35.2 | ||
| Entrez ID: 132625 | HGNC ID: HGNC:30949 | Ensembl Gene: ENSG00000179059 | OMIM ID: 614572 |
| Drug and gene relationship at DGIdb | |||
Expression of ZFP42:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFP42 | 132625 | 1554776_at | 0.1759 | 0.3828 | |
| GSE26886 | ZFP42 | 132625 | 1554777_at | 0.0038 | 0.9755 | |
| GSE45670 | ZFP42 | 132625 | 1554777_at | 0.0342 | 0.8284 | |
| GSE53622 | ZFP42 | 132625 | 55910 | 0.1304 | 0.6188 | |
| GSE53624 | ZFP42 | 132625 | 55910 | 0.4183 | 0.0943 | |
| GSE63941 | ZFP42 | 132625 | 1554776_at | 0.5745 | 0.6850 | |
| GSE77861 | ZFP42 | 132625 | 1554777_at | -0.1219 | 0.4150 | |
| SRP133303 | ZFP42 | 132625 | RNAseq | -0.1768 | 0.2280 | |
| SRP193095 | ZFP42 | 132625 | RNAseq | 0.0541 | 0.7288 | |
| SRP219564 | ZFP42 | 132625 | RNAseq | 0.8903 | 0.1344 | |
| TCGA | ZFP42 | 132625 | RNAseq | 4.3789 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZFP42 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZFP42:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFP42 | 132625 | 2 | 12 | 16 | |
| GSE20123 | ZFP42 | 132625 | 2 | 12 | 16 | |
| GSE43470 | ZFP42 | 132625 | 0 | 16 | 27 | |
| GSE46452 | ZFP42 | 132625 | 1 | 36 | 22 | |
| GSE47630 | ZFP42 | 132625 | 0 | 22 | 18 | |
| GSE54993 | ZFP42 | 132625 | 10 | 0 | 60 | |
| GSE54994 | ZFP42 | 132625 | 2 | 13 | 38 | |
| GSE60625 | ZFP42 | 132625 | 5 | 0 | 6 | |
| GSE74703 | ZFP42 | 132625 | 0 | 13 | 23 | |
| GSE74704 | ZFP42 | 132625 | 0 | 6 | 14 | |
| TCGA | ZFP42 | 132625 | 10 | 37 | 49 |
Total number of gains: 32; Total number of losses: 167; Total Number of normals: 289.
Somatic mutations of ZFP42:
Generating mutation plots.
Highly correlated genes for ZFP42:
Showing all 14 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFP42 | AMER1 | 0.738457 | 3 | 0 | 3 |
| ZFP42 | LRFN4 | 0.704717 | 3 | 0 | 3 |
| ZFP42 | FOXP4 | 0.702153 | 3 | 0 | 3 |
| ZFP42 | WDR83 | 0.697682 | 3 | 0 | 3 |
| ZFP42 | FLYWCH2 | 0.692652 | 3 | 0 | 3 |
| ZFP42 | RPUSD1 | 0.662503 | 3 | 0 | 3 |
| ZFP42 | ZIC1 | 0.641713 | 3 | 0 | 3 |
| ZFP42 | TKTL2 | 0.628113 | 3 | 0 | 3 |
| ZFP42 | NCLN | 0.618028 | 3 | 0 | 3 |
| ZFP42 | IRF2BP1 | 0.603856 | 3 | 0 | 3 |
| ZFP42 | GALNTL5 | 0.593511 | 3 | 0 | 3 |
| ZFP42 | SYNGAP1 | 0.56707 | 3 | 0 | 3 |
| ZFP42 | SV2C | 0.544588 | 4 | 0 | 3 |
| ZFP42 | GLDN | 0.543084 | 3 | 0 | 3 |
For details and further investigation, click here
