AADACL2

 

Full name: arylacetamide deacetylase like 2 Alias Symbol: MGC72001
Type: protein-coding gene Cytoband: 3q25.1
Entrez ID: 344752 HGNC ID: HGNC:24427 Ensembl Gene: ENSG00000197953 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of AADACL2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 AADACL2 344752 240420_at 0.1835 0.8173
GSE26886 AADACL2 344752 240420_at -0.2038 0.1621
GSE45670 AADACL2 344752 240420_at 0.5534 0.6048
GSE53622 AADACL2 344752 15732 -0.1359 0.6717
GSE53624 AADACL2 344752 15732 -0.7484 0.0059
GSE63941 AADACL2 344752 240420_at -0.0748 0.6276
GSE77861 AADACL2 344752 240420_at 0.6647 0.2751
SRP133303 AADACL2 344752 RNAseq 0.1900 0.5070
SRP159526 AADACL2 344752 RNAseq 3.6942 0.0001
SRP193095 AADACL2 344752 RNAseq 0.9034 0.0025
SRP219564 AADACL2 344752 RNAseq 0.6295 0.1148
TCGA AADACL2 344752 RNAseq 0.0762 0.9196

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by AADACL2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of AADACL2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 AADACL2 344752 21 0 9
GSE20123 AADACL2 344752 21 0 9
GSE43470 AADACL2 344752 23 0 20
GSE46452 AADACL2 344752 18 2 39
GSE47630 AADACL2 344752 19 3 18
GSE54993 AADACL2 344752 1 10 59
GSE54994 AADACL2 344752 37 1 15
GSE60625 AADACL2 344752 0 6 5
GSE74703 AADACL2 344752 20 0 16
GSE74704 AADACL2 344752 14 0 6
TCGA AADACL2 344752 73 1 22

Total number of gains: 247; Total number of losses: 23; Total Number of normals: 218.  

 

Somatic mutations of AADACL2:

 

Generating mutation plots.

 

Highly correlated genes for AADACL2:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
AADACL2MAGEF10.606095303
AADACL2LINC011330.597003403
AADACL2B4GALNT30.523649403
AADACL2P2RY10.515299603

For details and further investigation, click here