| Full name: beta-1,4-N-acetyl-galactosaminyltransferase 3 | Alias Symbol: B4GalNac-T3|FLJ16224|FLJ40362 | ||
| Type: protein-coding gene | Cytoband: 12p13.33 | ||
| Entrez ID: 283358 | HGNC ID: HGNC:24137 | Ensembl Gene: ENSG00000139044 | OMIM ID: 612220 |
| Drug and gene relationship at DGIdb | |||
Expression of B4GALNT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | B4GALNT3 | 283358 | 229909_at | 0.0282 | 0.9828 | |
| GSE26886 | B4GALNT3 | 283358 | 229203_at | 0.0004 | 0.9980 | |
| GSE45670 | B4GALNT3 | 283358 | 229909_at | 1.1180 | 0.0004 | |
| GSE53622 | B4GALNT3 | 283358 | 36702 | 1.5372 | 0.0000 | |
| GSE53624 | B4GALNT3 | 283358 | 36702 | 0.9555 | 0.0000 | |
| GSE63941 | B4GALNT3 | 283358 | 1553727_at | 0.6361 | 0.0128 | |
| GSE77861 | B4GALNT3 | 283358 | 229909_at | 0.9063 | 0.0029 | |
| GSE97050 | B4GALNT3 | 283358 | A_24_P306892 | 1.3286 | 0.0555 | |
| SRP007169 | B4GALNT3 | 283358 | RNAseq | 2.6420 | 0.0000 | |
| SRP008496 | B4GALNT3 | 283358 | RNAseq | 2.4859 | 0.0000 | |
| SRP064894 | B4GALNT3 | 283358 | RNAseq | 0.0109 | 0.9772 | |
| SRP133303 | B4GALNT3 | 283358 | RNAseq | 0.9702 | 0.0362 | |
| SRP159526 | B4GALNT3 | 283358 | RNAseq | 1.9606 | 0.0004 | |
| SRP193095 | B4GALNT3 | 283358 | RNAseq | 0.1936 | 0.6072 | |
| SRP219564 | B4GALNT3 | 283358 | RNAseq | -0.2945 | 0.7309 | |
| TCGA | B4GALNT3 | 283358 | RNAseq | -0.3818 | 0.0203 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by B4GALNT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of B4GALNT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | B4GALNT3 | 283358 | 9 | 4 | 17 | |
| GSE20123 | B4GALNT3 | 283358 | 8 | 4 | 18 | |
| GSE43470 | B4GALNT3 | 283358 | 8 | 3 | 32 | |
| GSE46452 | B4GALNT3 | 283358 | 10 | 1 | 48 | |
| GSE47630 | B4GALNT3 | 283358 | 12 | 2 | 26 | |
| GSE54993 | B4GALNT3 | 283358 | 1 | 10 | 59 | |
| GSE54994 | B4GALNT3 | 283358 | 10 | 2 | 41 | |
| GSE60625 | B4GALNT3 | 283358 | 0 | 1 | 10 | |
| GSE74703 | B4GALNT3 | 283358 | 7 | 2 | 27 | |
| GSE74704 | B4GALNT3 | 283358 | 5 | 2 | 13 | |
| TCGA | B4GALNT3 | 283358 | 41 | 7 | 48 |
Total number of gains: 111; Total number of losses: 38; Total Number of normals: 339.
Somatic mutations of B4GALNT3:
Generating mutation plots.
Highly correlated genes for B4GALNT3:
Showing top 20/575 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| B4GALNT3 | SESN3 | 0.76711 | 3 | 0 | 3 |
| B4GALNT3 | MRPL35 | 0.717596 | 3 | 0 | 3 |
| B4GALNT3 | FLAD1 | 0.712628 | 4 | 0 | 4 |
| B4GALNT3 | BLACAT1 | 0.712429 | 3 | 0 | 3 |
| B4GALNT3 | PLCG2 | 0.706903 | 3 | 0 | 3 |
| B4GALNT3 | PI3 | 0.694906 | 4 | 0 | 4 |
| B4GALNT3 | ACACA | 0.689376 | 3 | 0 | 3 |
| B4GALNT3 | DLX5 | 0.688529 | 7 | 0 | 6 |
| B4GALNT3 | TMEM104 | 0.687193 | 3 | 0 | 3 |
| B4GALNT3 | MAP7 | 0.686505 | 3 | 0 | 3 |
| B4GALNT3 | NUP85 | 0.68387 | 4 | 0 | 4 |
| B4GALNT3 | ABCF3 | 0.682842 | 5 | 0 | 5 |
| B4GALNT3 | SLC22A18 | 0.681977 | 3 | 0 | 3 |
| B4GALNT3 | CDCA2 | 0.680188 | 3 | 0 | 3 |
| B4GALNT3 | UHRF1 | 0.679018 | 4 | 0 | 4 |
| B4GALNT3 | PDIA4 | 0.677924 | 4 | 0 | 4 |
| B4GALNT3 | TIMELESS | 0.676502 | 5 | 0 | 4 |
| B4GALNT3 | DHRS13 | 0.675145 | 4 | 0 | 4 |
| B4GALNT3 | CXADR | 0.672595 | 3 | 0 | 3 |
| B4GALNT3 | DMKN | 0.671507 | 3 | 0 | 3 |
For details and further investigation, click here
