AFAP1-AS1

 

Full name: AFAP1 antisense RNA 1 Alias Symbol: MGC10981
Type: non-coding RNA Cytoband: 4p16.1
Entrez ID: 84740 HGNC ID: HGNC:28141 Ensembl Gene: ENSG00000272620 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of AFAP1-AS1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 AFAP1-AS1 84740 223779_at 1.5187 0.1617
GSE26886 AFAP1-AS1 84740 223779_at 1.3137 0.0007
GSE45670 AFAP1-AS1 84740 223779_at 0.5383 0.1418
GSE53622 AFAP1-AS1 84740 148562 0.5765 0.0131
GSE53624 AFAP1-AS1 84740 148562 0.5766 0.0002
GSE63941 AFAP1-AS1 84740 223779_at 1.3753 0.3936
GSE77861 AFAP1-AS1 84740 223779_at -0.0574 0.5744
SRP133303 AFAP1-AS1 84740 RNAseq 0.5159 0.0069
SRP159526 AFAP1-AS1 84740 RNAseq 2.6318 0.0004
SRP193095 AFAP1-AS1 84740 RNAseq -0.2338 0.6056

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by AFAP1-AS1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of AFAP1-AS1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 AFAP1-AS1 84740 0 18 12
GSE20123 AFAP1-AS1 84740 0 18 12
GSE43470 AFAP1-AS1 84740 0 17 26
GSE46452 AFAP1-AS1 84740 1 36 22
GSE47630 AFAP1-AS1 84740 1 19 20
GSE54993 AFAP1-AS1 84740 10 0 60
GSE54994 AFAP1-AS1 84740 3 12 38
GSE60625 AFAP1-AS1 84740 0 0 11
GSE74703 AFAP1-AS1 84740 0 13 23
GSE74704 AFAP1-AS1 84740 0 10 10

Total number of gains: 15; Total number of losses: 143; Total Number of normals: 234.  

 

Somatic mutations of AFAP1-AS1:

 

Generating mutation plots.

 

Highly correlated genes for AFAP1-AS1:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
AFAP1-AS1ZNF5260.788639303
AFAP1-AS1METTL230.627381303
AFAP1-AS1CD3EAP0.594338303
AFAP1-AS1KLHDC7B0.539111403

For details and further investigation, click here