| Full name: kelch domain containing 7B | Alias Symbol: MGC16635 | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 113730 | HGNC ID: HGNC:25145 | Ensembl Gene: ENSG00000130487 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KLHDC7B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHDC7B | 113730 | 236285_at | 1.3070 | 0.4242 | |
| GSE26886 | KLHDC7B | 113730 | 1552639_at | 0.2660 | 0.2445 | |
| GSE45670 | KLHDC7B | 113730 | 1552639_at | 0.4985 | 0.0017 | |
| GSE53622 | KLHDC7B | 113730 | 38408 | 0.9496 | 0.0000 | |
| GSE53624 | KLHDC7B | 113730 | 38408 | 0.5995 | 0.0000 | |
| GSE63941 | KLHDC7B | 113730 | 1552639_at | 0.1406 | 0.7628 | |
| GSE77861 | KLHDC7B | 113730 | 1552639_at | 0.1398 | 0.1087 | |
| GSE97050 | KLHDC7B | 113730 | A_24_P117410 | 1.3007 | 0.1846 | |
| SRP064894 | KLHDC7B | 113730 | RNAseq | 2.3186 | 0.0000 | |
| SRP133303 | KLHDC7B | 113730 | RNAseq | 2.9095 | 0.0000 | |
| SRP159526 | KLHDC7B | 113730 | RNAseq | 0.6482 | 0.4299 | |
| TCGA | KLHDC7B | 113730 | RNAseq | 1.6444 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by KLHDC7B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHDC7B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHDC7B | 113730 | 3 | 8 | 19 | |
| GSE20123 | KLHDC7B | 113730 | 3 | 8 | 19 | |
| GSE43470 | KLHDC7B | 113730 | 2 | 8 | 33 | |
| GSE46452 | KLHDC7B | 113730 | 31 | 2 | 26 | |
| GSE47630 | KLHDC7B | 113730 | 9 | 4 | 27 | |
| GSE54993 | KLHDC7B | 113730 | 4 | 6 | 60 | |
| GSE54994 | KLHDC7B | 113730 | 11 | 8 | 34 | |
| GSE60625 | KLHDC7B | 113730 | 5 | 0 | 6 | |
| GSE74703 | KLHDC7B | 113730 | 2 | 6 | 28 | |
| GSE74704 | KLHDC7B | 113730 | 1 | 4 | 15 | |
| TCGA | KLHDC7B | 113730 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of KLHDC7B:
Generating mutation plots.
Highly correlated genes for KLHDC7B:
Showing top 20/166 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHDC7B | MDK | 0.712429 | 5 | 0 | 4 |
| KLHDC7B | DTNB | 0.703667 | 3 | 0 | 3 |
| KLHDC7B | ZBP1 | 0.688251 | 5 | 0 | 4 |
| KLHDC7B | FERMT3 | 0.684702 | 4 | 0 | 4 |
| KLHDC7B | NAPSA | 0.681592 | 4 | 0 | 3 |
| KLHDC7B | CD7 | 0.676164 | 6 | 0 | 5 |
| KLHDC7B | PLD4 | 0.67476 | 3 | 0 | 3 |
| KLHDC7B | MYO7A | 0.668761 | 5 | 0 | 4 |
| KLHDC7B | LAG3 | 0.665663 | 4 | 0 | 3 |
| KLHDC7B | COL7A1 | 0.663222 | 4 | 0 | 3 |
| KLHDC7B | ENTPD6 | 0.654412 | 3 | 0 | 3 |
| KLHDC7B | GLDC | 0.652774 | 3 | 0 | 3 |
| KLHDC7B | IL21R | 0.64763 | 4 | 0 | 3 |
| KLHDC7B | TMC8 | 0.646542 | 5 | 0 | 3 |
| KLHDC7B | REC8 | 0.643871 | 4 | 0 | 3 |
| KLHDC7B | HPCAL1 | 0.633976 | 3 | 0 | 3 |
| KLHDC7B | DGKZ | 0.63316 | 6 | 0 | 4 |
| KLHDC7B | FCGR1B | 0.631343 | 5 | 0 | 4 |
| KLHDC7B | GNLY | 0.630027 | 5 | 0 | 3 |
| KLHDC7B | SH2D2A | 0.623717 | 6 | 0 | 4 |
For details and further investigation, click here
