AGBL1

 

Full name: ATP/GTP binding protein like 1 Alias Symbol: FLJ32310|CCP4
Type: protein-coding gene Cytoband: 15q25.3
Entrez ID: 123624 HGNC ID: HGNC:26504 Ensembl Gene: ENSG00000273540 OMIM ID: 615496
Drug and gene relationship at DGIdb

 

Expression of AGBL1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 AGBL1 123624 1553447_at -0.0340 0.9107
GSE26886 AGBL1 123624 1553447_at -0.2475 0.0246
GSE45670 AGBL1 123624 1553447_at -0.0099 0.9359
GSE53622 AGBL1 123624 95766 0.3245 0.0090
GSE53624 AGBL1 123624 95766 0.3888 0.0015
GSE63941 AGBL1 123624 1553447_at -0.0979 0.5232
GSE77861 AGBL1 123624 1553447_at -0.0829 0.4400
TCGA AGBL1 123624 RNAseq 2.9282 0.0012

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by AGBL1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of AGBL1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 AGBL1 123624 8 1 21
GSE20123 AGBL1 123624 8 1 21
GSE43470 AGBL1 123624 5 4 34
GSE46452 AGBL1 123624 3 7 49
GSE47630 AGBL1 123624 8 10 22
GSE54993 AGBL1 123624 4 6 60
GSE54994 AGBL1 123624 6 6 41
GSE60625 AGBL1 123624 4 0 7
GSE74703 AGBL1 123624 4 3 29
GSE74704 AGBL1 123624 4 1 15
TCGA AGBL1 123624 16 14 66

Total number of gains: 70; Total number of losses: 53; Total Number of normals: 365.  

 

Somatic mutations of AGBL1:

 

Generating mutation plots.

 

Highly correlated genes for AGBL1:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
AGBL1CATSPERG0.670921303
AGBL1CASP100.636584303
AGBL1TTTY110.568869503
AGBL1MYO15A0.565347303
AGBL1LINC003150.564829303
AGBL1PAPPA20.509442403

For details and further investigation, click here