IGSF5

 

Full name: immunoglobulin superfamily member 5 Alias Symbol: JAM4
Type: protein-coding gene Cytoband: 21q22.2
Entrez ID: 150084 HGNC ID: HGNC:5952 Ensembl Gene: ENSG00000183067 OMIM ID: 610638
Drug and gene relationship at DGIdb

 

IGSF5 involved pathways:

KEGG pathway Description View
hsa04530Tight junction

 

Expression of IGSF5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IGSF5 150084 243027_at 0.0320 0.9233
GSE26886 IGSF5 150084 243027_at 0.0072 0.9537
GSE45670 IGSF5 150084 243027_at 0.1575 0.0980
GSE53622 IGSF5 150084 98347 -0.5875 0.0000
GSE53624 IGSF5 150084 98347 -0.1094 0.1168
GSE63941 IGSF5 150084 243027_at 0.1829 0.5698
GSE77861 IGSF5 150084 243027_at -0.0118 0.9443
SRP133303 IGSF5 150084 RNAseq -0.1822 0.4714
TCGA IGSF5 150084 RNAseq -1.7105 0.0339

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by IGSF5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of IGSF5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 IGSF5 150084 2 11 17
GSE20123 IGSF5 150084 2 11 17
GSE43470 IGSF5 150084 0 10 33
GSE46452 IGSF5 150084 1 21 37
GSE47630 IGSF5 150084 6 17 17
GSE54993 IGSF5 150084 8 1 61
GSE54994 IGSF5 150084 3 8 42
GSE60625 IGSF5 150084 0 0 11
GSE74703 IGSF5 150084 0 8 28
GSE74704 IGSF5 150084 1 7 12
TCGA IGSF5 150084 8 41 47

Total number of gains: 31; Total number of losses: 135; Total Number of normals: 322.  

 

Somatic mutations of IGSF5:

 

Generating mutation plots.

 

Highly correlated genes for IGSF5:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IGSF5WIPF30.69711303
IGSF5SEMA4G0.596697303
IGSF5CNDP10.581512303
IGSF5NRSN20.555332303
IGSF5PTPRD0.520306303
IGSF5OR2A40.516475303

For details and further investigation, click here