OR2A4

 

Full name: olfactory receptor family 2 subfamily A member 4 Alias Symbol: 
Type: protein-coding gene Cytoband: 6q23.2
Entrez ID: 79541 HGNC ID: HGNC:14729 Ensembl Gene: ENSG00000180658 OMIM ID: 
Drug and gene relationship at DGIdb

 

OR2A4 involved pathways:

KEGG pathway Description View
hsa04740Olfactory transduction

 

Expression of OR2A4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OR2A4 79541 233493_at 0.0015 0.9987
GSE26886 OR2A4 79541 233493_at -0.1606 0.1301
GSE45670 OR2A4 79541 233493_at -0.0184 0.8977
GSE63941 OR2A4 79541 233493_at 0.2894 0.2484
GSE77861 OR2A4 79541 233493_at -0.0311 0.7314
SRP007169 OR2A4 79541 RNAseq 0.5211 0.5246
SRP064894 OR2A4 79541 RNAseq -0.1309 0.7282
SRP133303 OR2A4 79541 RNAseq -0.5393 0.0964
SRP159526 OR2A4 79541 RNAseq 0.1182 0.8804
SRP193095 OR2A4 79541 RNAseq 0.0699 0.7790
SRP219564 OR2A4 79541 RNAseq -0.4522 0.5264
TCGA OR2A4 79541 RNAseq 0.3854 0.1541

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by OR2A4 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of OR2A4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OR2A4 79541 2 5 23
GSE20123 OR2A4 79541 2 4 24
GSE43470 OR2A4 79541 5 0 38
GSE46452 OR2A4 79541 2 11 46
GSE47630 OR2A4 79541 9 4 27
GSE54993 OR2A4 79541 3 2 65
GSE54994 OR2A4 79541 9 7 37
GSE60625 OR2A4 79541 0 1 10
GSE74703 OR2A4 79541 4 0 32
GSE74704 OR2A4 79541 1 1 18
TCGA OR2A4 79541 11 18 67

Total number of gains: 48; Total number of losses: 53; Total Number of normals: 387.  

 

Somatic mutations of OR2A4:

 

Generating mutation plots.

 

Highly correlated genes for OR2A4:

 

Showing all 7 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OR2A4RAB39B0.61251303
OR2A4DND10.599944303
OR2A4SLC34A20.597034303
OR2A4GALNT80.595252303
OR2A4LRRC250.563078403
OR2A4KIAA05560.541317303
OR2A4IGSF50.516475303

For details and further investigation, click here