| Full name: semaphorin 4G | Alias Symbol: FLJ20590|KIAA1619 | ||
| Type: protein-coding gene | Cytoband: 10q24.31 | ||
| Entrez ID: 57715 | HGNC ID: HGNC:10735 | Ensembl Gene: ENSG00000095539 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
SEMA4G involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04360 | Axon guidance |
Expression of SEMA4G:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEMA4G | 57715 | 219194_at | 0.5284 | 0.1563 | |
| GSE20347 | SEMA4G | 57715 | 219194_at | 0.1100 | 0.3081 | |
| GSE23400 | SEMA4G | 57715 | 219194_at | -0.0802 | 0.0731 | |
| GSE26886 | SEMA4G | 57715 | 219194_at | 0.1100 | 0.5439 | |
| GSE29001 | SEMA4G | 57715 | 219194_at | -0.0183 | 0.9267 | |
| GSE38129 | SEMA4G | 57715 | 219194_at | -0.0281 | 0.8313 | |
| GSE45670 | SEMA4G | 57715 | 219194_at | 0.1792 | 0.0249 | |
| GSE53622 | SEMA4G | 57715 | 70094 | -0.2429 | 0.1913 | |
| GSE53624 | SEMA4G | 57715 | 70094 | -0.0903 | 0.4079 | |
| GSE63941 | SEMA4G | 57715 | 219194_at | 0.3249 | 0.1465 | |
| GSE77861 | SEMA4G | 57715 | 219194_at | -0.0229 | 0.9093 | |
| GSE97050 | SEMA4G | 57715 | A_23_P127068 | -0.0811 | 0.8094 | |
| SRP064894 | SEMA4G | 57715 | RNAseq | -0.4786 | 0.0362 | |
| SRP133303 | SEMA4G | 57715 | RNAseq | -0.8484 | 0.0056 | |
| SRP159526 | SEMA4G | 57715 | RNAseq | 0.0171 | 0.9705 | |
| SRP193095 | SEMA4G | 57715 | RNAseq | -0.3179 | 0.4686 | |
| SRP219564 | SEMA4G | 57715 | RNAseq | -0.3367 | 0.5814 | |
| TCGA | SEMA4G | 57715 | RNAseq | -0.9974 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SEMA4G expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEMA4G:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEMA4G | 57715 | 1 | 8 | 21 | |
| GSE20123 | SEMA4G | 57715 | 1 | 7 | 22 | |
| GSE43470 | SEMA4G | 57715 | 0 | 8 | 35 | |
| GSE46452 | SEMA4G | 57715 | 0 | 11 | 48 | |
| GSE47630 | SEMA4G | 57715 | 2 | 14 | 24 | |
| GSE54993 | SEMA4G | 57715 | 8 | 0 | 62 | |
| GSE54994 | SEMA4G | 57715 | 1 | 12 | 40 | |
| GSE60625 | SEMA4G | 57715 | 0 | 0 | 11 | |
| GSE74703 | SEMA4G | 57715 | 0 | 5 | 31 | |
| GSE74704 | SEMA4G | 57715 | 0 | 4 | 16 | |
| TCGA | SEMA4G | 57715 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 97; Total Number of normals: 373.
Somatic mutations of SEMA4G:
Generating mutation plots.
Highly correlated genes for SEMA4G:
Showing top 20/387 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEMA4G | BCORL1 | 0.697812 | 5 | 0 | 5 |
| SEMA4G | DPF3 | 0.674728 | 5 | 0 | 5 |
| SEMA4G | LINC01312 | 0.669342 | 3 | 0 | 3 |
| SEMA4G | EFCC1 | 0.66394 | 4 | 0 | 4 |
| SEMA4G | DRD1 | 0.662423 | 3 | 0 | 3 |
| SEMA4G | DAB2IP | 0.662389 | 3 | 0 | 3 |
| SEMA4G | ADAM22 | 0.660088 | 7 | 0 | 7 |
| SEMA4G | POU2F1 | 0.654155 | 3 | 0 | 3 |
| SEMA4G | NTNG1 | 0.647446 | 4 | 0 | 4 |
| SEMA4G | GP2 | 0.645921 | 5 | 0 | 5 |
| SEMA4G | ANKRD26 | 0.644993 | 4 | 0 | 4 |
| SEMA4G | ZBTB37 | 0.643323 | 3 | 0 | 3 |
| SEMA4G | NEUROD6 | 0.64226 | 6 | 0 | 5 |
| SEMA4G | TSTD2 | 0.641983 | 3 | 0 | 3 |
| SEMA4G | BMP15 | 0.639982 | 6 | 0 | 5 |
| SEMA4G | CDH18 | 0.63689 | 3 | 0 | 3 |
| SEMA4G | ZFP92 | 0.635227 | 3 | 0 | 3 |
| SEMA4G | USP21 | 0.634834 | 3 | 0 | 3 |
| SEMA4G | ZNF81 | 0.633587 | 3 | 0 | 3 |
| SEMA4G | BCL9 | 0.63308 | 6 | 0 | 6 |
For details and further investigation, click here
