KLHL40

 

Full name: kelch like family member 40 Alias Symbol: SRYP|NEM8
Type: protein-coding gene Cytoband: 3p22.1
Entrez ID: 131377 HGNC ID: HGNC:30372 Ensembl Gene: ENSG00000157119 OMIM ID: 615340
Drug and gene relationship at DGIdb

 

Expression of KLHL40:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KLHL40 131377 1555044_a_at 0.0591 0.8543
GSE26886 KLHL40 131377 1555044_a_at -0.0436 0.7886
GSE45670 KLHL40 131377 1555044_a_at -0.0238 0.7751
GSE53622 KLHL40 131377 46754 -0.2276 0.0889
GSE53624 KLHL40 131377 46754 -0.1551 0.0462
GSE63941 KLHL40 131377 1555044_a_at 0.0833 0.4408
GSE77861 KLHL40 131377 1555044_a_at -0.1275 0.3839

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by KLHL40 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of KLHL40:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KLHL40 131377 0 19 11
GSE20123 KLHL40 131377 0 19 11
GSE43470 KLHL40 131377 0 21 22
GSE46452 KLHL40 131377 2 17 40
GSE47630 KLHL40 131377 1 24 15
GSE54993 KLHL40 131377 7 2 61
GSE54994 KLHL40 131377 1 34 18
GSE60625 KLHL40 131377 5 0 6
GSE74703 KLHL40 131377 0 17 19
GSE74704 KLHL40 131377 0 13 7
TCGA KLHL40 131377 1 71 24

Total number of gains: 17; Total number of losses: 237; Total Number of normals: 234.  

 

Somatic mutations of KLHL40:

 

Generating mutation plots.

 

Highly correlated genes for KLHL40:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KLHL40LINC004210.618488303
KLHL40SPNS30.617286303
KLHL40PRM20.568364503
KLHL40DPEP30.565184303

For details and further investigation, click here