NWD1

 

Full name: NACHT and WD repeat domain containing 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 19p13.11
Entrez ID: 284434 HGNC ID: HGNC:27619 Ensembl Gene: ENSG00000188039 OMIM ID: 616250
Drug and gene relationship at DGIdb

 

Expression of NWD1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 NWD1 284434 112578 0.0025 0.9805
GSE53624 NWD1 284434 112578 -0.1536 0.0485
GSE97050 NWD1 284434 A_33_P3519250 -0.0164 0.9431
SRP064894 NWD1 284434 RNAseq -0.6727 0.0619
SRP133303 NWD1 284434 RNAseq -0.7819 0.0004
SRP159526 NWD1 284434 RNAseq -0.4571 0.5181
SRP193095 NWD1 284434 RNAseq -0.3241 0.0613
SRP219564 NWD1 284434 RNAseq 1.7665 0.0185
TCGA NWD1 284434 RNAseq -1.5695 0.0004

Upregulated datasets: 1; Downregulated datasets: 1.  

 

Survival by NWD1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NWD1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NWD1 284434 4 3 23
GSE20123 NWD1 284434 3 2 25
GSE43470 NWD1 284434 2 6 35
GSE46452 NWD1 284434 47 1 11
GSE47630 NWD1 284434 4 8 28
GSE54993 NWD1 284434 15 4 51
GSE54994 NWD1 284434 6 14 33
GSE60625 NWD1 284434 9 0 2
GSE74703 NWD1 284434 2 4 30
GSE74704 NWD1 284434 0 1 19
TCGA NWD1 284434 17 9 70

Total number of gains: 109; Total number of losses: 52; Total Number of normals: 327.  

 

Somatic mutations of NWD1:

 

Generating mutation plots.

 

Highly correlated genes for NWD1:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NWD1NUDT16L10.686003303
NWD1FOXA30.679416303
NWD1SCARA50.674379303
NWD1ANKAR0.643404303

For details and further investigation, click here