| Full name: DND microRNA-mediated repression inhibitor 1 | Alias Symbol: MGC34750|RBMS4 | ||
| Type: protein-coding gene | Cytoband: 5q31.3 | ||
| Entrez ID: 373863 | HGNC ID: HGNC:23799 | Ensembl Gene: ENSG00000256453 | OMIM ID: 609385 |
| Drug and gene relationship at DGIdb | |||
Expression of DND1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DND1 | 373863 | 57739_at | -0.2325 | 0.7093 | |
| GSE20347 | DND1 | 373863 | 57739_at | -0.2325 | 0.1567 | |
| GSE23400 | DND1 | 373863 | 222070_at | -0.1771 | 0.0000 | |
| GSE26886 | DND1 | 373863 | 57739_at | -0.4447 | 0.0550 | |
| GSE29001 | DND1 | 373863 | 57739_at | -0.2986 | 0.4434 | |
| GSE38129 | DND1 | 373863 | 57739_at | -0.0284 | 0.9207 | |
| GSE45670 | DND1 | 373863 | 57739_at | 0.2673 | 0.1453 | |
| GSE63941 | DND1 | 373863 | 57739_at | 1.2637 | 0.0003 | |
| GSE77861 | DND1 | 373863 | 222070_at | -0.1228 | 0.2824 | |
| GSE97050 | DND1 | 373863 | A_32_P42054 | 0.1244 | 0.5667 | |
| SRP007169 | DND1 | 373863 | RNAseq | -0.6857 | 0.1787 | |
| SRP064894 | DND1 | 373863 | RNAseq | 0.4352 | 0.0295 | |
| SRP133303 | DND1 | 373863 | RNAseq | 0.0299 | 0.9195 | |
| SRP159526 | DND1 | 373863 | RNAseq | 0.0065 | 0.9837 | |
| SRP193095 | DND1 | 373863 | RNAseq | -0.2782 | 0.0239 | |
| SRP219564 | DND1 | 373863 | RNAseq | -0.0113 | 0.9821 | |
| TCGA | DND1 | 373863 | RNAseq | -0.0950 | 0.2865 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DND1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of DND1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DND1 | 373863 | 3 | 11 | 16 | |
| GSE20123 | DND1 | 373863 | 4 | 11 | 15 | |
| GSE43470 | DND1 | 373863 | 2 | 10 | 31 | |
| GSE46452 | DND1 | 373863 | 0 | 27 | 32 | |
| GSE47630 | DND1 | 373863 | 0 | 20 | 20 | |
| GSE54993 | DND1 | 373863 | 9 | 1 | 60 | |
| GSE54994 | DND1 | 373863 | 2 | 14 | 37 | |
| GSE60625 | DND1 | 373863 | 0 | 0 | 11 | |
| GSE74703 | DND1 | 373863 | 2 | 7 | 27 | |
| GSE74704 | DND1 | 373863 | 3 | 5 | 12 | |
| TCGA | DND1 | 373863 | 4 | 37 | 55 |
Total number of gains: 29; Total number of losses: 143; Total Number of normals: 316.
Somatic mutations of DND1:
Generating mutation plots.
Highly correlated genes for DND1:
Showing top 20/518 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DND1 | IGFL1 | 0.762949 | 3 | 0 | 3 |
| DND1 | KIAA1217 | 0.711795 | 3 | 0 | 3 |
| DND1 | PTCH2 | 0.709073 | 4 | 0 | 4 |
| DND1 | ADAP1 | 0.704844 | 3 | 0 | 3 |
| DND1 | KCNMB2 | 0.697824 | 3 | 0 | 3 |
| DND1 | RAB3IL1 | 0.696054 | 4 | 0 | 4 |
| DND1 | NCR2 | 0.68799 | 6 | 0 | 6 |
| DND1 | MEGF11 | 0.684407 | 3 | 0 | 3 |
| DND1 | SEMA3F | 0.676269 | 7 | 0 | 6 |
| DND1 | CLTCL1 | 0.674811 | 4 | 0 | 4 |
| DND1 | NEUROD2 | 0.671536 | 3 | 0 | 3 |
| DND1 | MIR210HG | 0.670145 | 3 | 0 | 3 |
| DND1 | AKR1B10 | 0.666346 | 4 | 0 | 3 |
| DND1 | C10orf90 | 0.666296 | 3 | 0 | 3 |
| DND1 | SRCIN1 | 0.663911 | 3 | 0 | 3 |
| DND1 | MFSD6L | 0.654884 | 3 | 0 | 3 |
| DND1 | GABRD | 0.654281 | 3 | 0 | 3 |
| DND1 | MARCO | 0.653544 | 3 | 0 | 3 |
| DND1 | SBNO2 | 0.651787 | 4 | 0 | 4 |
| DND1 | SH2D1B | 0.651484 | 4 | 0 | 4 |
For details and further investigation, click here
