| Full name: leucine rich repeat containing 25 | Alias Symbol: MAPA|FLJ38116 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 126364 | HGNC ID: HGNC:29806 | Ensembl Gene: ENSG00000175489 | OMIM ID: 607518 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC25 | 126364 | 1559502_s_at | -0.0975 | 0.8450 | |
| GSE26886 | LRRC25 | 126364 | 1559502_s_at | 0.1625 | 0.6003 | |
| GSE45670 | LRRC25 | 126364 | 1559502_s_at | -0.0245 | 0.8823 | |
| GSE53622 | LRRC25 | 126364 | 62427 | 0.3292 | 0.0268 | |
| GSE53624 | LRRC25 | 126364 | 62427 | 0.3411 | 0.0155 | |
| GSE63941 | LRRC25 | 126364 | 1559502_s_at | 0.3461 | 0.1446 | |
| GSE77861 | LRRC25 | 126364 | 1559502_s_at | -0.0558 | 0.8373 | |
| GSE97050 | LRRC25 | 126364 | A_23_P165136 | 0.4682 | 0.3114 | |
| SRP007169 | LRRC25 | 126364 | RNAseq | 1.5659 | 0.0308 | |
| SRP008496 | LRRC25 | 126364 | RNAseq | 1.2674 | 0.0133 | |
| SRP064894 | LRRC25 | 126364 | RNAseq | 0.7193 | 0.0204 | |
| SRP133303 | LRRC25 | 126364 | RNAseq | 0.2533 | 0.1223 | |
| SRP159526 | LRRC25 | 126364 | RNAseq | 0.5111 | 0.3213 | |
| SRP193095 | LRRC25 | 126364 | RNAseq | 0.7582 | 0.0000 | |
| SRP219564 | LRRC25 | 126364 | RNAseq | 1.1125 | 0.0367 | |
| TCGA | LRRC25 | 126364 | RNAseq | 0.2232 | 0.1817 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by LRRC25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC25 | 126364 | 4 | 4 | 22 | |
| GSE20123 | LRRC25 | 126364 | 3 | 2 | 25 | |
| GSE43470 | LRRC25 | 126364 | 2 | 5 | 36 | |
| GSE46452 | LRRC25 | 126364 | 47 | 1 | 11 | |
| GSE47630 | LRRC25 | 126364 | 4 | 8 | 28 | |
| GSE54993 | LRRC25 | 126364 | 15 | 4 | 51 | |
| GSE54994 | LRRC25 | 126364 | 6 | 13 | 34 | |
| GSE60625 | LRRC25 | 126364 | 9 | 0 | 2 | |
| GSE74703 | LRRC25 | 126364 | 2 | 3 | 31 | |
| GSE74704 | LRRC25 | 126364 | 0 | 2 | 18 | |
| TCGA | LRRC25 | 126364 | 16 | 10 | 70 |
Total number of gains: 108; Total number of losses: 52; Total Number of normals: 328.
Somatic mutations of LRRC25:
Generating mutation plots.
Highly correlated genes for LRRC25:
Showing top 20/228 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC25 | SPI1 | 0.80394 | 3 | 0 | 3 |
| LRRC25 | DOK2 | 0.781745 | 3 | 0 | 3 |
| LRRC25 | C19orf38 | 0.766465 | 3 | 0 | 3 |
| LRRC25 | C1QA | 0.764753 | 3 | 0 | 3 |
| LRRC25 | FPR1 | 0.758219 | 3 | 0 | 3 |
| LRRC25 | TNFSF8 | 0.756678 | 3 | 0 | 3 |
| LRRC25 | PIK3R5 | 0.754256 | 4 | 0 | 4 |
| LRRC25 | DPEP2 | 0.753603 | 3 | 0 | 3 |
| LRRC25 | CCL3 | 0.743575 | 3 | 0 | 3 |
| LRRC25 | CD163 | 0.741445 | 4 | 0 | 4 |
| LRRC25 | C1orf162 | 0.726578 | 4 | 0 | 3 |
| LRRC25 | MRC1 | 0.723667 | 4 | 0 | 4 |
| LRRC25 | CD37 | 0.720898 | 3 | 0 | 3 |
| LRRC25 | MYO1F | 0.716887 | 4 | 0 | 4 |
| LRRC25 | VSIG4 | 0.716747 | 5 | 0 | 5 |
| LRRC25 | LAIR1 | 0.71614 | 4 | 0 | 3 |
| LRRC25 | MPEG1 | 0.712306 | 5 | 0 | 4 |
| LRRC25 | NKG7 | 0.710314 | 3 | 0 | 3 |
| LRRC25 | TCN2 | 0.709419 | 3 | 0 | 3 |
| LRRC25 | IGSF6 | 0.709327 | 3 | 0 | 3 |
For details and further investigation, click here
