PRAC1

 

Full name: PRAC1 small nuclear protein Alias Symbol: 
Type: protein-coding gene Cytoband: 17q21.32
Entrez ID: 84366 HGNC ID: HGNC:30591 Ensembl Gene: ENSG00000159182 OMIM ID: 609819
Screen Evidence:

 

Expression of PRAC1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PRAC1 84366 230784_at -0.0833 0.7954
GSE26886 PRAC1 84366 230784_at 0.1939 0.0524
GSE45670 PRAC1 84366 230784_at -0.0393 0.6611
GSE53622 PRAC1 84366 46610 -0.2969 0.0110
GSE53624 PRAC1 84366 46610 -0.6067 0.0092
GSE63941 PRAC1 84366 230784_at -0.0499 0.7343
GSE77861 PRAC1 84366 230784_at -0.0171 0.8710

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PRAC1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of PRAC1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PRAC1 84366 6 2 22
GSE20123 PRAC1 84366 6 2 22
GSE43470 PRAC1 84366 3 0 40
GSE46452 PRAC1 84366 32 0 27
GSE47630 PRAC1 84366 9 0 31
GSE54993 PRAC1 84366 2 4 64
GSE54994 PRAC1 84366 10 6 37
GSE60625 PRAC1 84366 4 0 7
GSE74703 PRAC1 84366 3 0 33
GSE74704 PRAC1 84366 4 1 15

Total number of gains: 79; Total number of losses: 15; Total Number of normals: 298.  

 

Somatic mutations of PRAC1:

 

Generating mutation plots.

 

Highly correlated genes for PRAC1:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PRAC1TRAF3IP2-AS10.585937403
PRAC1APOF0.545408403
PRAC1FAM181A0.543555303
PRAC1LPA0.532715403

For details and further investigation, click here